(Q34445947)

2 August 2017

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title

Searching for genetic determinants of human aging and longevity: opportunities and challenges (English)

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2 August 2017

1

Jan Vijg

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2 August 2017

Nathalie van Orsouw

2

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2 August 2017

language of work or name

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1 January 2002

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Mechanisms of Ageing and Development

2 August 2017

published in

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2 August 2017

volume

123

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2 August 2017

issue

2-3

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2 August 2017

page(s)

195-205

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Genetic epidemiology of single-nucleotide polymorphisms.

2 August 2017

cites work

1 reference

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7 January 2021

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

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7 January 2021

DNA multiallelic systems reveal gene/longevity associations not detected by diallelic systems. The APOB locus

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7 January 2021

A simple system for automated two-dimensional electrophoresis: applications to genetic testing

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7 January 2021

Common BRCA1 variants and susceptibility to breast and ovarian cancer in the general population

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7 January 2021

Genetic testing: the problems and the promise

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7 January 2021

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Length-independent separation of DNA restriction fragments in two-dimensional gel electrophoresis

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7 January 2021

Mutator phenotype of Werner syndrome is characterized by extensive deletions

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7 January 2021

Molecular analysis of phenylketonuria in Denmark: 99% of the mutations detected by denaturing gradient gel electrophoresis

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7 January 2021

Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis

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7 January 2021

Prospects for whole-genome linkage disequilibrium mapping of common disease genes

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7 January 2021

Genetic analysis of ageing: role of oxidative damage and environmental stresses.

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7 January 2021

High-speed, multicolor fluorescent two-dimensional gene scanning

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7 January 2021

A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

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7 January 2021

Siblings of centenarians live longer

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7 January 2021

Validity of reported age and centenarian prevalence in New England

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7 January 2021

Searching for genetic determinants in the new millennium

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7 January 2021

Evolutionary theory in gerontology

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7 January 2021

Genetic associations with human longevity at the APOE and ACE loci

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7 January 2021

BRCA1 sequence analysis in women at high risk for susceptibility mutations. Risk factor analysis and implications for genetic testing.

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7 January 2021

Attachment of a 40-base-pair G + C-rich sequence (GC-clamp) to genomic DNA fragments by the polymerase chain reaction results in improved detection of single-base changes

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7 January 2021

Mutational scanning of large genes by extensive PCR multiplexing and two-dimensional electrophoresis: application to the RB1 gene

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7 January 2021

A highly accurate, low cost test for BRCA1 mutations

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7 January 2021

Breast cancer genes and DNA repair.

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7 January 2021

Understanding the biology of aging: the key to prevention and therapy

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7 January 2021

PLEIOTROPY, NATURAL SELECTION, AND THE EVOLUTION OF SENESCENCE

1 reference

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7 January 2021

Positional cloning of the Werner's syndrome gene

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7 January 2021

10.1016/S0047-6374(01)00346-3

Identifiers

DOI

1 reference

2 August 2017

1 reference