(Q34446169)

2 August 2017

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title

Recent highlights in the development of new antiviral drugs (English)

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2 August 2017

Erik De Clercq

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publication date

1 October 2005

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Current Opinion in Microbiology

2 August 2017

published in

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2 August 2017

volume

8

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2 August 2017

issue

5

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2 August 2017

page(s)

552-560

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SARS--beginning to understand a new virus

2 August 2017

cites work

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12 December 2020

Herpes simplex virus helicase-primase inhibitors are active in animal models of human disease

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12 December 2020

Antiviral drugs in current clinical use.

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12 December 2020

Small molecules targeting severe acute respiratory syndrome human coronavirus

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12 December 2020

Amino acid changes within conserved region III of the herpes simplex virus and human cytomegalovirus DNA polymerases confer resistance to 4-oxo-dihydroquinolines, a novel class of herpesvirus antiviral agents

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12 December 2020

Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: a randomized study of treatment duration and ribavirin dose

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12 December 2020

Treatment of Ebola virus infection with a recombinant inhibitor of factor VIIa/tissue factor: a study in rhesus monkeys

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12 December 2020

An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus

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12 December 2020

Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection

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12 December 2020

Adherence to combination therapy enhances sustained response in genotype-1-infected patients with chronic hepatitis C.

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12 December 2020

The predominant mechanism by which ribavirin exerts its antiviral activity in vitro against flaviviruses and paramyxoviruses is mediated by inhibition of IMP dehydrogenase

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12 December 2020

Enhanced inhibition of orthopoxvirus replication in vitro by alkoxyalkyl esters of cidofovir and cyclic cidofovir

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12 December 2020

A new millennium conundrum: how to use a powerful class of influenza anti-neuraminidase drugs (NAIs) in the community

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12 December 2020

Ether lipid-ester prodrugs of acyclic nucleoside phosphonates: activity against adenovirus replication in vitro

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12 December 2020

3-deazaneplanocin A induces massively increased interferon-alpha production in Ebola virus-infected mice

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12 December 2020

Mannose-specific plant lectins from the Amaryllidaceae family qualify as efficient microbicides for prevention of human immunodeficiency virus infection

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12 December 2020

Profile of resistance of human immunodeficiency virus to mannose-specific plant lectins

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12 December 2020

Inhibition of dengue virus serotypes 1 to 4 in vero cell cultures with morpholino oligomers

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12 December 2020

Potential of acyclic nucleoside phosphonates in the treatment of DNA virus and retrovirus infections

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12 December 2020

Oral treatment of cowpox and vaccinia virus infections in mice with ether lipid esters of cidofovir.

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12 December 2020

Therapeutic potential of nucleoside/nucleotide analogues against poxvirus infections

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12 December 2020

Clinical Potential of the Acyclic Nucleoside Phosphonates Cidofovir, Adefovir, and Tenofovir in Treatment of DNA Virus and Retrovirus Infections

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12 December 2020

A 193-amino acid fragment of the SARS coronavirus S protein efficiently binds angiotensin-converting enzyme 2

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12 December 2020

Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus

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12 December 2020

New approaches toward anti-HIV chemotherapy

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12 December 2020

Design and development of oral drugs for the prophylaxis and treatment of smallpox infection.

1 reference

12 December 2020

In search of a novel anti-HIV drug: multidisciplinary coordination in the discovery of 4-[[4-[[4-[(1E)-2-cyanoethenyl]-2,6-dimethylphenyl]amino]-2- pyrimidinyl]amino]benzonitrile (R278474, rilpivirine).

1 reference

12 December 2020

Cidofovir in the treatment of poxvirus infections

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12 December 2020

Neuraminidase sequence analysis and susceptibilities of influenza virus clinical isolates to zanamivir and oseltamivir.

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12 December 2020

Highly potent and selective inhibition of varicella-zoster virus replication by bicyclic furo[2,3-d]pyrimidine nucleoside analogues

1 reference

12 December 2020

Interferons, Interferon Inducers, and Interferon-Ribavirin in Treatment of Flavivirus-Induced Encephalitis in Mice

1 reference

12 December 2020

The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor

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12 December 2020

Antivirals and antiviral strategies

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12 December 2020

Antiviral potential of a new generation of acyclic nucleoside phosphonates, the 6-[2-(phosphonomethoxy)alkoxy]-2,4-diaminopyrimidines

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12 December 2020

Identification of a small molecule that inhibits herpes simplex virus DNA Polymerase subunit interactions and viral replication

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12 December 2020

Interaction between heptad repeat 1 and 2 regions in spike protein of SARS-associated coronavirus: implications for virus fusogenic mechanism and identification of fusion inhibitors

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12 December 2020

Deoxythreosyl phosphonate nucleosides as selective anti-HIV agents

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12 December 2020

Marked depletion of glycosylation sites in HIV-1 gp120 under selection pressure by the mannose-specific plant lectins of Hippeastrum hybrid and Galanthus nivalis.

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12 December 2020

Effects of four antiviral substances on lethal vaccinia virus (IHD strain) respiratory infections in mice

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12 December 2020

The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen

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12 December 2020

Emerging anti-HIV drugs

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12 December 2020

Mechanism of action of a pestivirus antiviral compound

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12 December 2020

Treatment of lethal Ebola virus infection in mice with a single dose of an S-adenosyl-L-homocysteine hydrolase inhibitor

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12 December 2020

Strategies in the design of antiviral drugs

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12 December 2020

Update on human herpesvirus 6 biology, clinical features, and therapy

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12 December 2020

Efficacy of cidofovir in a murine model of disseminated progressive vaccinia

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12 December 2020

Ribonucleoside Analogue That Blocks Replication of Bovine Viral Diarrhea and Hepatitis C Viruses in Culture

1 reference

12 December 2020

Severe acute respiratory syndrome-related coronavirus is inhibited by interferon- alpha

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12 December 2020

RNA virus error catastrophe: direct molecular test by using ribavirin

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12 December 2020

Hepatitis C therapeutics: current status and emerging strategies

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12 December 2020

Pegylated interferon-alpha protects type 1 pneumocytes against SARS coronavirus infection in macaques

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12 December 2020

Resistant influenza A viruses in children treated with oseltamivir: descriptive study

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12 December 2020

A novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase

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12 December 2020

Susceptibilities of several clinical varicella-zoster virus (VZV) isolates and drug-resistant VZV strains to bicyclic furano pyrimidine nucleosides

1 reference

12 December 2020

Specific Inhibition of Bovine Viral Diarrhea Virus Replicase

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12 December 2020

Potent neutralization of severe acute respiratory syndrome (SARS) coronavirus by a human mAb to S1 protein that blocks receptor association

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12 December 2020

Antiadenovirus activities of several classes of nucleoside and nucleotide analogues

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12 December 2020

Potent, selective and cell-mediated inhibition of human herpesvirus 6 at an early stage of viral replication by the non-nucleoside compound CMV423.

1 reference

12 December 2020

New helicase-primase inhibitors as drug candidates for the treatment of herpes simplex disease

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12 December 2020

Potent in vivo antiviral activity of the herpes simplex virus primase-helicase inhibitor BAY 57-1293.

1 reference

12 December 2020

10.1016/J.MIB.2005.08.010

Identifiers

DOI

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2 August 2017

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