Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q34453555)
Watch
English
Progress in targeting HIV-1 entry.
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
16182193
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16182193%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
review article
1 reference
stated in
Europe PubMed Central
title
Progress in targeting HIV-1 entry
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
16182193
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16182193%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
author
Rudolf Fluckiger
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
16182193
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16182193%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
author name string
Hugues J-P Ryser
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
16182193
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16182193%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
publication date
1 August 2005
1 reference
stated in
Europe PubMed Central
PubMed ID
16182193
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16182193%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
published in
Drug Discovery Today
1 reference
stated in
Europe PubMed Central
PubMed ID
16182193
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16182193%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
volume
10
1 reference
stated in
Europe PubMed Central
PubMed ID
16182193
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16182193%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
issue
16
1 reference
stated in
Europe PubMed Central
PubMed ID
16182193
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16182193%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
page(s)
1085-1094
1 reference
stated in
Europe PubMed Central
PubMed ID
16182193
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16182193%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
cites work
Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of human immunodeficiency virus infection by agents that interfere with thiol-disulfide interchange upon virus-receptor interaction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The catalytic activity of protein disulfide isomerase is involved in human immunodeficiency virus envelope-mediated membrane fusion after CD4 cell binding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibitors of protein-disulfide isomerase prevent cleavage of disulfide bonds in receptor-bound glycoprotein 120 and prevent HIV-1 entry.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein-disulfide isomerase-mediated reduction of two disulfide bonds of HIV envelope glycoprotein 120 occurs post-CXCR4 binding and is required for fusion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thiol/disulfide exchange is a prerequisite for CXCR4-tropic HIV-1 envelope-mediated T-cell fusion during viral entry.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kinetics
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Core structure of gp41 from the HIV envelope glycoprotein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Atomic structure of the ectodomain from HIV-1 gp41
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of an unliganded simian immunodeficiency virus gp120 core
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Localized changes in the gp120 envelope glycoprotein confer resistance to human immunodeficiency virus entry inhibitors BMS-806 and #155.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional analysis of the disulfide-bonded loop/chain reversal region of human immunodeficiency virus type 1 gp41 reveals a critical role in gp120-gp41 association
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional evolution of the HIV-1 envelope glycoprotein 120 association site of glycoprotein 41.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of the ectodomain of the gp41 transmembrane envelope protein of human immunodeficiency virus type 1 in late steps of the membrane fusion process
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence that the transition of HIV-1 gp41 into a six-helix bundle, not the bundle configuration, induces membrane fusion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-1 envelope proteins complete their folding into six-helix bundles immediately after fusion pore formation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The C- and the N-terminal regions of glycoprotein 41 ectodomain fuse membranes enriched and not enriched with cholesterol, respectively
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The HIV Env-mediated fusion reaction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Small-molecule inhibitors of HIV-1 entry block receptor-induced conformational changes in the viral envelope glycoproteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Virus entry as a target for anti-HIV intervention
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The next generation of HIV/AIDS drugs: novel and developmental antiHIV drugs and targets
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The entry of entry inhibitors: a fusion of science and medicine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
New advances in HIV entry inhibitors development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Recent advances in understanding the molecular mechanisms of HIV-1 entry and fusion: revisiting current targets and considering new options for therapeutic intervention
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prospects of HIV-1 entry inhibitors as novel therapeutics
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Small-molecule antagonists of CCR5 and CXCR4: a promising new class of anti-HIV-1 drugs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
New approaches toward anti-HIV chemotherapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Discovery of 4-benzoyl-1-[(4-methoxy-1H- pyrrolo[2,3-b]pyridin-3-yl)oxoacetyl]-2- (R)-methylpiperazine (BMS-378806): a novel HIV-1 attachment inhibitor that interferes with CD4-gp120 interactions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A small molecule HIV-1 inhibitor that targets the HIV-1 envelope and inhibits CD4 receptor binding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Treatment of advanced human immunodeficiency virus type 1 disease with the viral entry inhibitor PRO 542.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rational design of a CD4 mimic that inhibits HIV-1 entry and exposes cryptic neutralization epitopes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antiretroviral activity of the anti-CD4 monoclonal antibody TNX-355 in patients infected with HIV type 1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of human immunodeficiency virus replication by a dual CCR5/CXCR4 antagonist
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SCH-C (SCH 351125), an orally bioavailable, small molecule antagonist of the chemokine receptor CCR5, is a potent inhibitor of HIV-1 infection in vitro and in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of the mechanism by which the small-molecule CCR5 antagonists SCH-351125 and SCH-350581 inhibit human immunodeficiency virus type 1 entry.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Potent, broad-spectrum inhibition of human immunodeficiency virus type 1 by the CCR5 monoclonal antibody PRO 140
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-chemotherapy and -prophylaxis: new drugs, leads and approaches
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A duodenally absorbable CXC chemokine receptor 4 antagonist, KRH-1636, exhibits a potent and selective anti-HIV-1 activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Capture of an early fusion-active conformation of HIV-1 gp41
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD4-induced T-20 binding to human immunodeficiency virus type 1 gp120 blocks interaction with the CXCR4 coreceptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peptides trap the human immunodeficiency virus type 1 envelope glycoprotein fusion intermediate at two sites
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Emergence of a drug-dependent human immunodeficiency virus type 1 variant during therapy with the T20 fusion inhibitor.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Presence of closely spaced protein thiols on the surface of mammalian cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inter-subunit disulfide bonds in soluble HIV-1 envelope glycoprotein trimers.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peptides corresponding to the heptad repeat motifs in the transmembrane protein (gp41) of human immunodeficiency virus type 1 elicit antibodies to receptor-activated conformations of the envelope glycoprotein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The prefusogenic intermediate of HIV-1 gp41 contains exposed C-peptide regions.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Safety, pharmacokinetics, and antiviral activity of AMD3100, a selective CXCR4 receptor inhibitor, in HIV-1 infection.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903550-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1359-6446(05)03550-6
1 reference
stated in
Europe PubMed Central
PubMed ID
16182193
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16182193%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
PubMed ID
16182193
1 reference
stated in
Europe PubMed Central
PubMed ID
16182193
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16182193%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit