(Q34456861)

2 August 2017

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title

Chromosomal translocations in sarcomas: prospects for therapy (English)

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2 August 2017

Tomescu O

1

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2 August 2017

Barr FG

series ordinal

2

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2 August 2017

publication date

1 December 2001

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Trends in Molecular Medicine

2 August 2017

published in

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2 August 2017

volume

7

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2 August 2017

issue

12

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2 August 2017

page(s)

554-559

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Mechanism for transcriptional gain of function resulting from chromosomal translocation in alveolar rhabdomyosarcoma

2 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902244-4

7 January 2021

Inhibition of apoptosis by normal and aberrant Fli-1 and erg proteins involved in human solid tumors and leukemias

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7 January 2021

Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation.

1 reference

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7 January 2021

cDNA microarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion oncogene.

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7 January 2021

Common and variant gene fusions predict distinct clinical phenotypes in rhabdomyosarcoma

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902244-4

7 January 2021

Does expression of different EWS chimeric transcripts define clinically distinct risk groups of Ewing tumor patients?

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902244-4

7 January 2021

SYT-SSX gene fusion as a determinant of morphology and prognosis in synovial sarcoma

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902244-4

7 January 2021

Molecular assays for chromosomal translocations in the diagnosis of pediatric soft tissue sarcomas

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7 January 2021

Predictive potential of testing for bone marrow involvement in Ewing tumor patients by RT-PCR: a preliminary evaluation.

1 reference

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7 January 2021

Regulatory role of mevalonate and N-linked glycosylation in proliferation and expression of the EWS/FLI-1 fusion protein in Ewing's sarcoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902244-4

7 January 2021

The insulin-like growth factor-I receptor is required for EWS/FLI-1 transformation of fibroblasts

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902244-4

7 January 2021

Translation arrest by oligodeoxynucleotides complementary to mRNA coding sequences yields polypeptides of predetermined length

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902244-4

7 January 2021

Role of RNase H in hybrid-arrested translation by antisense oligonucleotides

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7 January 2021

Induction of apoptosis in rhabdomyosarcoma cells through down-regulation of PAX proteins.

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7 January 2021

Transcriptional modulation of the anti-apoptotic protein BCL-XL by the paired box transcription factors PAX3 and PAX3/FKHR

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902244-4

7 January 2021

EWS-Fli1 antisense oligodeoxynucleotide inhibits proliferation of human Ewing's sarcoma and primitive neuroectodermal tumor cells

1 reference

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7 January 2021

Preferential down-regulation of phospholipase C-beta in Ewing's sarcoma cells transfected with antisense EWS-Fli-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902244-4

7 January 2021

Repression of the gene encoding the TGF-beta type II receptor is a major target of the EWS-FLI1 oncoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902244-4

7 January 2021

EWS fli-1 antisense nanocapsules inhibits ewing sarcoma-related tumor in mice

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7 January 2021

Modification of EWS/WT1 functional properties by phosphorylation

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7 January 2021

Regulating the neoplastic phenotype using engineered transcriptional repressors

1 reference

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7 January 2021

An engineered PAX3-KRAB transcriptional repressor inhibits the malignant phenotype of alveolar rhabdomyosarcoma cells harboring the endogenous PAX3-FKHR oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902244-4

7 January 2021

Tumor cell viability in clear cell sarcoma requires DNA binding activity of the EWS/ATF1 fusion protein

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902244-4

7 January 2021

Targeting tumor specific translocations in sarcomas in pediatric patients for immunotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902244-4

7 January 2021

The PAX3-FKHR fusion protein created by the t(2;13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than PAX3

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902244-4

7 January 2021

Regulated expression of the diphtheria toxin A chain by a tumor-specific chimeric transcription factor results in selective toxicity for alveolar rhabdomyosarcoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902244-4

7 January 2021

The cellular oncogene EWS/activating transcription factor 1 is unable to activate adenovirus-borne promoters: implications for cytotoxic prodrug therapy of malignant melanoma of soft parts

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902244-4

7 January 2021

Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902244-4

7 January 2021

Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902244-4

7 January 2021

The der(17)t(X;17)(p11;q25) of human alveolar soft part sarcoma fuses the TFE3 transcription factor gene to ASPL, a novel gene at 17q25

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902244-4

7 January 2021

EWS and ATF-1 gene fusion induced by t(12;22) translocation in malignant melanoma of soft parts

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902244-4

7 January 2021

Deregulation of the platelet-derived growth factor B-chain gene via fusion with collagen gene COL1A1 in dermatofibrosarcoma protuberans and giant-cell fibroblastoma.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902244-4

7 January 2021

Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902244-4

7 January 2021

Combinatorial generation of variable fusion proteins in the Ewing family of tumours.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902244-4

7 January 2021

Fusion of an ETS-family gene, EIAF, to EWS by t(17;22)(q12;q12) chromosome translocation in an undifferentiated sarcoma of infancy

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902244-4

7 January 2021

A new member of the ETS family fused to EWS in Ewing tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902244-4

7 January 2021

A novel ETV6-NTRK3 gene fusion in congenital fibrosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902244-4

7 January 2021

TPM3-ALK and TPM4-ALK oncogenes in inflammatory myofibroblastic tumors

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902244-4

7 January 2021

Oncogenic conversion of a novel orphan nuclear receptor by chromosome translocation

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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902244-4

7 January 2021

Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902244-4

7 January 2021

Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Kruppel-associated box in human synovial sarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902244-4

7 January 2021

A novel fusion gene, SYT-SSX4, in synovial sarcoma.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902244-4

7 January 2021

10.1016/S1471-4914(01)02244-4

Identifiers

DOI

1 reference

2 August 2017

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