(Q34463833)

2 August 2017

Structural biology. Structural basis for Notch1 engagement of Delta-like 4 (English)

1 reference

2 August 2017

1 reference

Kevin M Jude

2

0 references

Maxence V. Nachury

object named as

Maxence V Nachury

4

0 references

author name string

Vincent C Luca

1

1 reference

2 August 2017

Nathan W Pierce

3

1 reference

2 August 2017

Suzanne Fischer

5

1 reference

2 August 2017

K Christopher Garcia

6

1 reference

2 August 2017

language of work or name

English

0 references

publication date

1 February 2015

1 reference

2 August 2017

1 reference

2 August 2017

347

1 reference

2 August 2017

6224

1 reference

2 August 2017

847-853

1 reference

Fringe-mediated extension of O-linked fucose in the ligand-binding region of Notch1 increases binding to mammalian Notch ligands

2 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

Structural Analysis Uncovers Lipid-Binding Properties of Notch Ligands

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

Intrinsic selectivity of Notch 1 for Delta-like 4 over Delta-like 1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

Regulation of innate and adaptive immunity by Notch

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

Blockade of individual Notch ligands and receptors controls graft-versus-host disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

Molecular basis for Jagged-1/Serrate ligand recognition by the Notch receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

A mutation in EGF repeat-8 of Notch discriminates between Serrate/Jagged and Delta family ligands

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

Generation of anti-Notch antibodies and their application in blocking Notch signalling in neural stem cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

Structural basis of Wnt recognition by Frizzled

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

Fringe benefits: functional and structural impacts of O-glycosylation on the extracellular domain of Notch receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

The Notch1-Dll4 signaling pathway regulates mouse postnatal lymphatic development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

Cis-interactions between Notch and Delta generate mutually exclusive signalling states

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

Therapeutic antibody targeting of individual Notch receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

The many facets of Notch ligands

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

A conserved face of the Jagged/Serrate DSL domain is involved in Notch trans-activation and cis-inhibition

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

Cis interactions of immunoreceptors with MHC and non-MHC ligands

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

Rumi is a CAP10 domain glycosyltransferase that modifies Notch and is required for Notch signaling.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

Structural basis for autoinhibition of Notch

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

DSL ligand endocytosis physically dissociates Notch1 heterodimers before activating proteolysis can occur

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

NOTCH2 mutations cause Alagille syndrome, a heterogeneous disorder of the notch signaling pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

Jagged1 (JAG1) mutations in Alagille syndrome: increasing the mutation detection rate

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

Jagged1 signals in the postnatal subventricular zone are required for neural stem cell self-renewal.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

The divergent DSL ligand Dll3 does not activate Notch signaling but cell autonomously attenuates signaling induced by other DSL ligands

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

Mutations in NOTCH1 cause aortic valve disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

Highly conserved O-fucose sites have distinct effects on Notch1 function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

Fringe modulation of Jagged1-induced Notch signaling requires the action of beta 4galactosyltransferase-1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

Jagged1 mutations in alagille syndrome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

Fringe differentially modulates Jagged1 and Delta1 signalling through Notch1 and Notch2.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

Solution structure of an EGF module pair from the Plasmodium falciparum merozoite surface protein 1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

Notch signaling: cell fate control and signal integration in development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

Presenilin is required for activity and nuclear access of Notch in Drosophila

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

Structural conservation of Notch receptors and ligands

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

Fringe modulates Notch-ligand interactions.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

Cholesterol modification of hedgehog signaling proteins in animal development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

Specific EGF repeats of Notch mediate interactions with Delta and serrate: Implications for notch as a multifunctional receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

Notch signaling in development and disease.

6 July 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1261093

Regulation of notch signaling by o-linked fucose.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1261093

A secreted Delta1-Fc fusion protein functions both as an activator and inhibitor of Notch1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1261093

Localization of the delta-like-1-binding site in human Notch-1 and its modulation by calcium affinity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1261093

Structural and functional properties of the human notch-1 ligand binding region.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1261093

Regions of Drosophila Notch that contribute to ligand binding and the modulatory influence of Fringe.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1261093

The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1261093

Isolating and engineering human antibodies using yeast surface display

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1261093

The conserved Bardet-Biedl syndrome proteins assemble a coat that traffics membrane proteins to cilia

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1261093

A noncommercial dual luciferase enzyme assay system for reporter gene analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1261093

Lysine methylation as a routine rescue strategy for protein crystallization

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1261093

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1261093

Protein structure prediction on the Web: a case study using the Phyre server

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1261093

PHENIX: building new software for automated crystallographic structure determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1261093

Collaboration gets the most out of software

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1261093

Coot: model-building tools for molecular graphics

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1261093

JLigand: a graphical tool for the CCP4 template-restraint library

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1261093

Inference of macromolecular assemblies from crystalline state

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1261093

Overview of the CCP4 suite and current developments

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1261093

The DynDom database of protein domain motions

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1261093

Crystal Structure of Reovirus Attachment Protein σ1 in Complex with Sialylated Oligosaccharides

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1261093

Feed-back mechanisms affecting Notch activation at the dorsoventral boundary in the Drosophila wing.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445638

27 October 2018

Identifiers

DOI

10.1126/SCIENCE.1261093

1 reference

2 August 2017

0 references

1 reference

2 August 2017

1 reference