(Q34464355)

English

Actinomycin D induces high-level resistance to thymidine analogs in replication of human immunodeficiency virus type 1 by interfering with host cell thymidine kinase expression.

scientific article published in January 2003

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12502817%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

Actinomycin D induces high-level resistance to thymidine analogs in replication of human immunodeficiency virus type 1 by interfering with host cell thymidine kinase expression (English)

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16 December 2019

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Richard A. Lempicki

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16 December 2019

Joseph W Adelsberger

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Joseph W Adelsberger

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16 December 2019

Michael W Baseler

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Michael W Baseler

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16 December 2019

H. Clifford Lane

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H Clifford Lane

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16 December 2019

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Tomozumi Imamichi

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16 December 2019

Michael A Murphy

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16 December 2019

Jun Yang

4

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16 December 2019

Catherine M Watkins

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16 December 2019

Steve C Berg

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16 December 2019

Jianhui Guo

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16 December 2019

Judith G Levin

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16 December 2019

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1 January 2003

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16 December 2019

Journal of Virology

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16 December 2019

77

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16 December 2019

2

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16 December 2019

1011-1020

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16 December 2019

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Relative replication fitness of a high-level 3'-azido-3'-deoxythymidine-resistant variant of human immunodeficiency virus type 1 possessing an amino acid deletion at codon 67 and a novel substitution (Thr-->Gly) at codon 69.

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High-level resistance to 3'-azido-3'-deoxythimidine due to a deletion in the reverse transcriptase gene of human immunodeficiency virus type 1

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The transcriptional inhibitors, actinomycin D and alpha-amanitin, activate the HIV-1 promoter and favor phosphorylation of the RNA polymerase II C-terminal domain

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The mechanism of actinomycin D-mediated inhibition of HIV-1 reverse transcription

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Human immunodeficiency virus type 1 genome activation induced by human T-cell leukemia virus type 1 Tax protein is through cooperation of NF-kappaB and Tat.

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6 July 2018

Actinomycin D inhibits human immunodeficiency virus type 1 minus-strand transfer in in vitro and endogenous reverse transcriptase assays

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Selectivity of F8-actinomycin D for RNA:DNA hybrids and its anti-leukemia activity

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Overexpression of a heterologous thymidine kinase delays apoptosis induced by factor deprivation and inhibitors of deoxynucleotide metabolism

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Actinomycin D binding to single-stranded DNA: sequence specificity and hemi-intercalation model from fluorescence and 1H NMR spectroscopy

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Sequence-specific actinomycin D binding to single-stranded DNA inhibits HIV reverse transcriptase and other polymerases

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Seminars in medicine of the Beth Israel Hospital, Boston. Pathogenesis of diseases induced by human lymphotropic virus type I infection

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Extracellular human T-cell lymphotropic virus type I Tax protein induces cytokine production in adult human microglial cells

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Isolation and characterization of a syncytium-inducing, macrophage/T-cell line-tropic human immunodeficiency virus type 1 isolate that readily infects chimpanzee cells in vitro and in vivo

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Effect of aphidicolin on avian sarcoma virus replication

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Establishment of infection by spleen necrosis virus: inhibition in stationary cells and the role of secondary infection

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Evidence for transcriptional and post-transcriptional control of the cellular thymidine kinase gene

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Regulation of human thymidine kinase during the cell cycle

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Identifiers

10.1128/JVI.77.2.1011-1020.2003

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12502817%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12502817%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12502817%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

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