(Q34466975)

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Blunted hypertensive effect of combined fructose and high-salt diet in gene-targeted mice lacking functional serum- and glucocorticoid-inducible kinase SGK1.

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9 January 2020

Blunted hypertensive effect of combined fructose and high-salt diet in gene-targeted mice lacking functional serum- and glucocorticoid-inducible kinase SGK1 (English)

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9 January 2020

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9 January 2020

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9 January 2020

Hartmut Osswald

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Hartmut Osswald

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9 January 2020

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Dan Yang Huang

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9 January 2020

Krishna M Boini

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9 January 2020

Björn Friedrich

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9 January 2020

Marco Metzger

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9 January 2020

Lothar Just

5

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9 January 2020

Peer Wulff

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9 January 2020

Florian Lang

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9 January 2020

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10 November 2005

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9 January 2020

American Journal of Physiology - Regulatory, Integrative and Comparative Physiology

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9 January 2020

290

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9 January 2020

4

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9 January 2020

R935-44

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9 January 2020

Role of SGK in hormonal regulation of epithelial sodium channel in A6 cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

The serum and glucocorticoid kinase sgk increases the abundance of epithelial sodium channels in the plasma membrane of Xenopus oocytes.

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

The metabolic syndrome X and peripheral cortisol synthesis

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Mineralocorticoid receptor knockout mice: pathophysiology of Na+ metabolism

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

The serum- and glucocorticoid-induced kinase is a physiological mediator of aldosterone action

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

The PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB.

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

The salt paradox of the early diabetic kidney is independent of renal innervation.

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Insulin-stimulated trafficking of ENaC in renal cells requires PI 3-kinase activity

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Real-time three-dimensional imaging of lipid signal transduction: apical membrane insertion of epithelial Na(+) channels

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

The shrinkage-activated Na(+) conductance of rat hepatocytes and its possible correlation to rENaC.

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Rapid upregulation of serum and glucocorticoid-regulated kinase (sgk) gene expression by corticosteroids in vivo

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Serum- and glucocorticoid-regulated kinase (SGK1) gene and blood pressure

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Twin studies in the analysis of minor physiological differences between individuals

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Association of the serum and glucocorticoid regulated kinase (sgk1) gene with QT interval

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Insulin receptors and renal sodium handling in hypertensive fructose-fed rats

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Cellular mechanisms of insulin resistance in rats with fructose-induced hypertension

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Epithelial sodium channel regulated by aldosterone-induced protein sgk.

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na(+) channel cell surface expression

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

The effects of glucose and insulin on renal electrolyte transport

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

A novel pathway of epithelial sodium channel activation involves a serum- and glucocorticoid-inducible kinase consensus motif in the C terminus of the channel's alpha-subunit

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Regulation of glucose transporter SGLT1 by ubiquitin ligase Nedd4-2 and kinases SGK1, SGK3, and PKB.

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

The relationship between hyperinsulinemia, hypertension and progressive renal disease

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Regulation of KCNE1-dependent K(+) current by the serum and glucocorticoid-inducible kinase (SGK) isoforms

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Regulation of the epithelial Ca2+ channel TRPV5 by the NHE regulating factor NHERF2 and the serum and glucocorticoid inducible kinase isoforms SGK1 and SGK3 expressed in Xenopus oocytes.

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

sgk: an essential convergence point for peptide and steroid hormone regulation of ENaC-mediated Na+ transport

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Dietary salt regulates renal SGK1 abundance: relevance to salt sensitivity in the Dahl rat.

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Stimulus-dependent regulation of serum and glucocorticoid inducible protein kinase (SGK) transcription, subcellular localization and enzymatic activity

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Salt-loading elevates blood pressure and aggravates insulin resistance in Wistar fatty rats: a possible role for enhanced Na+ -H+ exchanger activity.

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Activation of Na+/K+-ATPase by the serum and glucocorticoid-dependent kinase isoforms

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Attenuation of insulin-mediated pressor effect and nitric oxide release in rats with fructose-induced insulin resistance

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Impaired regulation of renal K+ elimination in the sgk1-knockout mouse.

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Early death due to defective neonatal lung liquid clearance in alpha-ENaC-deficient mice.

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Fructose-induced insulin resistance and hypertension in rats

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Genetic analysis of glucose tolerance in inbred mouse strains. Evidence for polygenic control.

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Regulation of channels by the serum and glucocorticoid-inducible kinase - implications for transport, excitability and cell proliferation

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Deranged transcriptional regulation of cell-volume-sensitive kinase hSGK in diabetic nephropathy

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Molecular genetics of human blood pressure variation

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Aldosterone induces rapid apical translocation of ENaC in early portion of renal collecting system: possible role of SGK.

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Present status of genetic mechanisms in hypertension

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Role of adenosine A(2B) receptors in vasodilation of rat pial artery and cerebral blood flow autoregulation

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Effect of insulin on renal sodium and uric acid handling in essential hypertension.

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Hoe 140 abolishes the blood pressure lowering effect of taurine in high fructose-fed rats

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

sgk is an aldosterone-induced kinase in the renal collecting duct. Effects on epithelial na+ channels

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Decrease in renal medullary endothelial nitric oxide synthase of fructose-fed, salt-sensitive hypertensive rats

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Requirement of PDZ domains for the stimulation of the epithelial Ca2+ channel TRPV5 by the NHE regulating factor NHERF2 and the serum and glucocorticoid inducible kinase SGK1

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Molecular requirements for the regulation of the renal outer medullary K+ channel ROMK1 by the serum- and glucocorticoid-inducible kinase SGK1

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

SGK1 regulation of epithelial sodium transport

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Stimulation of Xenopus oocyte Na(+),K(+)ATPase by the serum and glucocorticoid-dependent kinase sgk1.

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

AT(1) receptor inhibition does not reduce arterial wall hypertrophy or PDGF-A expression in renal hypertension

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Evidence for a causal role of the renin-angiotensin system in vascular dysfunction associated with insulin resistance

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Serum and glucocorticoid-regulated kinase modulates Nedd4-2-mediated inhibition of the epithelial Na+ channel

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Androgens are necessary for the development of fructose-induced hypertension

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Effects of dietary fat, NaCl, and fructose on renal sodium and water transporter abundances and systemic blood pressure

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Direct activation of the epithelial Na(+) channel by phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 3,4-bisphosphate produced by phosphoinositide 3-OH kinase

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Salt-sensitivity of proximal reabsorption alters macula densa salt and explains the paradoxical effect of dietary salt on glomerular filtration rate in diabetes mellitus.

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

SGK1 as a determinant of kidney function and salt intake in response to mineralocorticoid excess

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

SGK1: aldosterone-induced relay of Na+ transport regulation in distal kidney nephron cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Effects of the serine/threonine kinase SGK1 on the epithelial Na(+) channel (ENaC) and CFTR: implications for cystic fibrosis

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

SGK integrates insulin and mineralocorticoid regulation of epithelial sodium transport

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Impaired renal Na(+) retention in the sgk1-knockout mouse

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Concerted roles of SGK1 and the Na+/H+ exchanger regulatory factor 2 (NHERF2) in regulation of NHE3.

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Glucocorticoid activation of Na(+)/H(+) exchanger isoform 3 revisited. The roles of SGK1 and NHERF2

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

SGK1 increases Na,K-ATP cell-surface expression and function in Xenopus laevis oocytes.

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Gene therapy with human tissue kallikrein reduces hypertension and hyperinsulinemia in fructose-induced hypertensive rats.

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

Phosphoinositide 3-kinase is required for aldosterone-regulated sodium reabsorption.

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00382.2005

21 January 2018

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