(Q34468794)

2 August 2017

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title

Transforming functions of Simian Virus 40. (English)

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2 August 2017

Simian Virus 40

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Sáenz-Robles MT

1

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2 August 2017

Sullivan CS

series ordinal

2

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2 August 2017

Pipas JM

series ordinal

3

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2 August 2017

language of work or name

English

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publication date

1 November 2001

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2 August 2017

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2 August 2017

20

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2 August 2017

54

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2 August 2017

7899-7907

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1204936

2 August 2017

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Purified JC virus T and T' proteins differentially interact with the retinoblastoma family of tumor suppressor proteins

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Tissue-specific inactivation of p53 tumor suppression in the mouse.

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Transgenic mice harboring SV40 T-antigen genes develop characteristic brain tumors

21 January 2018

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SV40 large T antigen directed by regulatory elements of the human alpha-1-antitrypsin gene. A transgenic mouse system that exhibits stages in liver carcinogenesis

21 January 2018

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DnaJ/hsp40 chaperone domain of SV40 large T antigen promotes efficient viral DNA replication

21 January 2018

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Use of normal and transgenic mice to examine the relationship between terminal differentiation of intestinal epithelial cells and accumulation of their cell cycle regulators

21 January 2018

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Human COL2A1-directed SV40 T antigen expression in transgenic and chimeric mice results in abnormal skeletal development.

21 January 2018

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Uniform cell-autonomous tumorigenesis of the choroid plexus by papovavirus large T antigens

21 January 2018

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Tumorigenesis in transgenic mice in which the SV40 T antigen is driven by the brain-specific FGF1 promoter.

21 January 2018

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Bi-transgenic mice reveal that K-rasVal12 augments a p53-independent apoptosis when small intestinal villus enterocytes reenter the cell cycle

21 January 2018

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The role of the J domain of SV40 large T in cellular transformation

21 January 2018

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Association of p300 and CBP with simian virus 40 large T antigen

21 January 2018

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Novel mechanisms of E2F induction by BK virus large-T antigen: requirement of both the pRb-binding and the J domains

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

Metastatic hibernomas in transgenic mice expressing an alpha-amylase-SV40 T antigen hybrid gene

21 January 2018

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A transgenic mouse model of metastatic prostate cancer originating from neuroendocrine cells

21 January 2018

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The C3(1)/SV40 T-antigen transgenic mouse model of mammary cancer: ductal epithelial cell targeting with multistage progression to carcinoma

21 January 2018

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Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes

21 January 2018

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Expression of SV-40 T antigen in the small intestinal epithelium of transgenic mice results in proliferative changes in the crypt and reentry of villus-associated enterocytes into the cell cycle but has no apparent effect on cellular differentiation

21 January 2018

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Targeted expression of SV40 large T-antigen to visceral smooth muscle induces proliferation of contractile smooth muscle cells and results in megacolon

21 January 2018

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An unexpected role for p53 in augmenting SV40 large T antigen-mediated tumorigenesis.

21 January 2018

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Transgenic mouse model for neurocristopathy: Schwannomas and facial bone tumors

21 January 2018

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Transgenic mouse models that explore the multistep hypothesis of intestinal neoplasia

21 January 2018

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Expression of wild-type and mutant simian virus 40 large tumor antigens in villus-associated enterocytes of transgenic mice

21 January 2018

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Transgenic mouse models to study human mineralocorticoid receptor function in vivo

21 January 2018

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Three-dimensional solution structure of a single zinc finger DNA-binding domain

21 January 2018

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Simian virus 40 T antigen-induced amplification of pre-parietal cells in transgenic mice. Effects on other gastric epithelial cell lineages and evidence for a p53-independent apoptotic mechanism that operates in a committed progenitor

21 January 2018

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Solution structure of the origin DNA-binding domain of SV40 T-antigen

21 January 2018

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Conditional liver-specific expression of simian virus 40 T antigen leads to regulatable development of hepatic neoplasm in transgenic mice

21 January 2018

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Hyperplasia in multiple smooth muscle tissues in transgenic mice expressing a temperature-sensitive SV40 T-antigen under the control of smooth muscle alpha-actin regulatory sequences.

21 January 2018

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Regulation of apoptosis in transgenic mice by simian virus 40 T antigen-mediated inactivation of p53.

21 January 2018

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Pancreatic neoplasia induced by SV40 T-antigen expression in acinar cells of transgenic mice.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

Directed expression of simian virus 40 T-antigen in transgenic mice using the epidermal growth factor gene promoter

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

Coexpression of mutant p53 and p193 renders embryonic stem cell-derived cardiomyocytes responsive to the growth-promoting activities of adenoviral E1A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

Tumors of the retinal pigment epithelium metastasize to inguinal lymph nodes and spleen in tyrosinase-related protein 1/SV40 T antigen transgenic mice.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

Role of T antigen interactions with p53 in tumorigenesis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

Role of the amino-terminal domain of simian virus 40 early region in inducing tumors in secretin-expressing cells in transgenic mice

21 January 2018

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Multiple endocrine neoplasia induced by the promiscuous expression of a viral oncogene

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

The role of the SV40 ST antigen in cell growth promotion and transformation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

Inhibition of Rb and p53 is insufficient for SV40 T-antigen transformation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

Induction versus progression of brain tumor development: differential functions for the pRB- and p53-targeting domains of simian virus 40 T antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

Tissue-specific expression of kallikrein family transgenes in mice and rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

The J domain of papovaviral large tumor antigen is required for synergistic interaction with the POU-domain protein Tst-1/Oct6/SCIP.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

SV40 large T antigen functions at two distinct steps in virion assembly

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

The amino-terminal transforming region of simian virus 40 large T and small t antigens functions as a J domain.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

The molecular chaperone activity of simian virus 40 large T antigen is required to disrupt Rb-E2F family complexes by an ATP-dependent mechanism

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

ATP-dependent simian virus 40 T-antigen-Hsc70 complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

Species-specific elements in the large T-antigen J domain are required for cellular transformation and DNA replication by simian virus 40

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

Use of transgenic mice reveals cell-specific transformation by a simian virus 40 T-antigen amino-terminal mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

Simian virus 40 large T antigen binds a novel Bcl-2 homology domain 3-containing proapoptosis protein in the cytoplasm.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

The J domain of simian virus 40 large T antigen is required to functionally inactivate RB family proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

Hibernoma development in transgenic mice identifies brown adipose tissue as a novel target of aldosterone action.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

Development of colonic and pancreatic endocrine tumours in mice expressing a glucagon-SV40 T antigen transgene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

7 January 2021

Regression of primary hepatocarcinoma in cancer-prone transgenic mice by local interferon-gamma delivery is associated with macrophages recruitment and nitric oxide production

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

7 January 2021

Hyperplasia and tumors of the islets of Langerhans in mice bearing an elastase I-SV40 T-antigen fusion gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

7 January 2021

The amino-terminal region of SV40 large T antigen is sufficient to induce hepatic tumours in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

7 January 2021

Lymphotropic papovavirus early region is specifically regulated transgenic mice and efficiently induces neoplasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

7 January 2021

Identification of SV40 large T-antigen-associated proteins in cardiomyocytes from transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

7 January 2021

Glucagon gene regulatory region directs oncoprotein expression to neurons and pancreatic alpha cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

7 January 2021

Time-sensitive reversal of hyperplasia in transgenic mice expressing SV40 T antigen

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

7 January 2021

Examining the role of Paneth cells in the small intestine by lineage ablation in transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

7 January 2021

Lactation-induced WAP-SV40 Tag transgene expression in C57BL/6J mice leads to mammary carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

7 January 2021

Studies in Transgenic Mice Reveal Potential Relationships between Secretin-producing Cells and Other Endocrine Cell Types

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

7 January 2021

Common and unique features of T antigens encoded by the polyomavirus group

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

7 January 2021

Tiny T antigen: an autonomous polyomavirus T antigen amino-terminal domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

7 January 2021

A transgenic mouse model for the ductal carcinoma in situ (DCIS) of the mammary gland

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

7 January 2021

The DnaJ domain of polyomavirus large T antigen is required to regulate Rb family tumor suppressor function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

7 January 2021

p53-dependent apoptosis suppresses tumor growth and progression in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

7 January 2021

Adding an Rb-binding site to an N-terminally truncated simian virus 40 T antigen restores growth to high cell density, and the T common region in trans provides anchorage-independent growth and rapid growth in low serum concentrations.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

7 January 2021

A simian virus 40 large T-antigen segment containing amino acids 1 to 127 and expressed under the control of the rat elastase-1 promoter produces pancreatic acinar carcinomas in transgenic mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

7 January 2021

A transgenic mouse line that develops early-onset invasive gastric carcinoma provides a model for carcinoembryonic antigen-targeted tumor therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204936

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204936

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Dimensions Publication ID

2 August 2017

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1 reference