(Q34472177)

2 August 2017

title

L-carnitine is an endogenous HDAC inhibitor selectively inhibiting cancer cell growth in vivo and in vitro (English)

1 reference

2 August 2017

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Xuejun Wang

14

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author name string

Hongbiao Huang

1

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2 August 2017

Ningning Liu

2

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2 August 2017

Haiping Guo

3

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2 August 2017

Siyan Liao

4

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2 August 2017

Xiaofen Li

5

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2 August 2017

Changshan Yang

6

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2 August 2017

Shouting Liu

7

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2 August 2017

Wenbin Song

8

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2 August 2017

Chunjiao Liu

9

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2 August 2017

Lixia Guan

10

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2 August 2017

Bing Li

11

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2 August 2017

Li Xu

12

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2 August 2017

Change Zhang

13

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2 August 2017

Q Ping Dou

15

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2 August 2017

Jinbao Liu

16

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2 August 2017

language of work or name

English

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publication date

5 November 2012

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2 August 2017

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2 August 2017

volume

7

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2 August 2017

issue

11

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2 August 2017

page(s)

e49062

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Creative Commons Attribution 4.0 International

2 August 2017

copyright license

start time

5 November 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Gambogic acid enhances proteasome inhibitor-induced anticancer activity

6 July 2018

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Physiological levels of ATP negatively regulate proteasome function.

6 July 2018

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Regulation of cellular metabolism by protein lysine acetylation

6 July 2018

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Lysine acetylation targets protein complexes and co-regulates major cellular functions

6 July 2018

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Degradation of cyclin A is regulated by acetylation.

6 July 2018

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Progression of diethylnitrosamine-induced hepatic carcinogenesis in carnitine-depleted rats

6 July 2018

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Shikonin exerts antitumor activity via proteasome inhibition and cell death induction in vitro and in vivo.

6 July 2018

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Is cancer a disease of abnormal cellular metabolism? New angles on an old idea

6 July 2018

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Lysine acetylation: codified crosstalk with other posttranslational modifications

6 July 2018

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The age of crosstalk: phosphorylation, ubiquitination, and beyond

6 July 2018

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Safety, tolerability and symptom outcomes associated with L-carnitine supplementation in patients with cancer, fatigue, and carnitine deficiency: a phase I/II study

6 July 2018

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Cancer's molecular sweet tooth and the Warburg effect.

6 July 2018

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Essential fatty acids: biochemistry, physiology and pathology

6 July 2018

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Defective oxidative phosphorylation in thyroid oncocytic carcinoma is associated with pathogenic mitochondrial DNA mutations affecting complexes I and III.

6 July 2018

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Triple layer control: phosphorylation, acetylation and ubiquitination of FOXO proteins.

6 July 2018

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Mediator requirement for both recruitment and postrecruitment steps in transcription initiation

6 July 2018

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Why do cancers have high aerobic glycolysis?

6 July 2018

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Supplementation of L-carnitine in athletes: does it make sense?

6 July 2018

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Inhibition of p53 degradation by Mdm2 acetylation

6 July 2018

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6 July 2018

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Mitochondrial defects in cancer

6 July 2018

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Histone deacetylase inhibitors: a new class of potential therapeutic agents for cancer treatment.

6 July 2018

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Molecular enzymology of carnitine transfer and transport

6 July 2018

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Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation

6 July 2018

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Induction of apoptosis in U937 human leukemia cells by suberoylanilide hydroxamic acid (SAHA) proceeds through pathways that are regulated by Bcl-2/Bcl-XL, c-Jun, and p21CIP1, but independent of p53

6 July 2018

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Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

6 July 2018

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Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis

6 July 2018

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Rat liver carnitine palmitoyltransferase 1 forms an oligomeric complex within the outer mitochondrial membrane

6 July 2018

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Acetylation of p53 inhibits its ubiquitination by Mdm2.

21 January 2018

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Efficacy of l-carnitine administration on fatigue, nutritional status, oxidative stress, and related quality of life in 12 advanced cancer patients undergoing anticancer therapy

21 January 2018

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L-carnitine inhibits hepatocarcinogenesis via protection of mitochondria

21 January 2018

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Trichostatin A is a histone deacetylase inhibitor with potent antitumor activity against breast cancer in vivo.

21 January 2018

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Sanggenon C decreases tumor cell viability associated with proteasome inhibition

27 October 2018

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12 December 2020

Involvement of p21(Waf1/Cip1) and its cleavage by DEVD-caspase during apoptosis of colorectal cancer cells induced by butyrate

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12 December 2020

Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses the growth of prostate cancer cells in vitro and in vivo

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12 December 2020

Transcriptional activation of p21(WAF1/CIP1) by apicidin, a novel histone deacetylase inhibitor

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12 December 2020

Up-regulation of p21(WAF1/CIP1) by histone deacetylase inhibitors reduces their cytotoxicity

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12 December 2020

The mechanism of fatty acid uptake by heart mitochondria: an acylcarnitine-carnitine exchange

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12 December 2020

10.1371/JOURNAL.PONE.0049062

Identifiers

DOI

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2 August 2017

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2 August 2017

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