(Q34478795)

2 August 2017

Activation of phosphatidylinositol 3-kinase signaling by a mutant thyroid hormone beta receptor (English)

1 reference

2 August 2017

Fumihiko Furuya

1

1 reference

2 August 2017

John A Hanover

series ordinal

2

1 reference

2 August 2017

Sheue-yann Cheng

series ordinal

3

1 reference

2 August 2017

language of work or name

English

0 references

publication date

30 January 2006

1 reference

Proceedings of the National Academy of Sciences of the United States of America

2 August 2017

1 reference

2 August 2017

103

1 reference

2 August 2017

6

1 reference

2 August 2017

1780-1785

1 reference

Dual functions of the steroid hormone receptor coactivator 3 in modulating resistance to thyroid hormone

2 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413672

Chromosomal aberrations in cell lines derived from thyroid tumors spontaneously developed in TRbetaPV/PV mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413672

Thyroid hormone receptor mutations and disease: beyond thyroid hormone resistance

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413672

Gelatinases (MMP-2 and -9) and their natural inhibitors as prognostic indicators in solid cancers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413672

Phosphoinositide 3-kinase in disease: timing, location, and scaffolding

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413672

An unliganded thyroid hormone beta receptor activates the cyclin D1/cyclin-dependent kinase/retinoblastoma/E2F pathway and induces pituitary tumorigenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413672

mTOR: a protein kinase switching between life and death

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413672

Integrin-linked kinase: integrin's mysterious partner

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413672

The biology and clinical relevance of the PTEN tumor suppressor pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413672

Phosphoinositide 3-kinases as targets for therapeutic intervention

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413672

Integrin-linked kinase (ILK) in combination molecular targeting.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413672

Akt activation and localisation correlate with tumour invasion and oncogene expression in thyroid cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413672

Molecular basis of resistance to thyroid hormone.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413672

PTEN: one gene, many syndromes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413672

The role of integrin-linked kinase (ILK) in cancer progression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413672

6 July 2018

Nuclear lipid signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413672

The nuclear phosphoinositide 3-kinase/AKT pathway: a new second messenger system.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413672

Matrix metalloproteinases: a tail of a frog that became a prince

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413672

Direct interaction between the cytoplasmic tail of ADAM 12 and the Src homology 3 domain of p85alpha activates phosphatidylinositol 3-kinase in C2C12 cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413672

Mice with a targeted mutation in the thyroid hormone beta receptor gene exhibit impaired growth and resistance to thyroid hormone

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413672

Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413672

The SH3 and BH domains of the p85alpha adapter subunit play a critical role in regulating class Ia phosphoinositide 3-kinase function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413672

Somatic deletions and mutations in the Cowden disease gene, PTEN, in sporadic thyroid tumors.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413672

Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413672

Modulation of the transcriptional activity of thyroid hormone receptors by the tumor suppressor p53.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413672

Interaction of human beta 1 thyroid hormone receptor and its mutants with DNA and retinoid X receptor beta. T3 response element-dependent dominant negative potency

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413672

An essential role of domain D in the hormone-binding activity of human beta 1 thyroid hormone nuclear receptor.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413672

Characterization of seven novel mutations of the c-erbA beta gene in unrelated kindreds with generalized thyroid hormone resistance. Evidence for two "hot spot" regions of the ligand binding domain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413672

Increased expression of phosphorylated p70S6 kinase and Akt in papillary thyroid cancer tissues.

6 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510849103

Mice with a mutation in the thyroid hormone receptor beta gene spontaneously develop thyroid carcinoma: a mouse model of thyroid carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510849103

Alterations in genomic profiles during tumor progression in a mouse model of follicular thyroid carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510849103

Thyroid hormone induces rapid activation of Akt/protein kinase B-mammalian target of rapamycin-p70S6K cascade through phosphatidylinositol 3-kinase in human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510849103

Differential expression of thyroid hormone receptor isoforms dictates the dominant negative activity of mutant Beta receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0510849103

Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1413672

Overexpression and overactivation of Akt in thyroid carcinoma

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16446424

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mutant thyroid hormone receptor beta represses the expression and transcriptional activity of peroxisome proliferator-activated receptor gamma during thyroid carcinogenesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16446424

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

AKT activation promotes metastasis in a mouse model of follicular thyroid carcinoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16446424

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0510849103

1 reference

2 August 2017

0 references

1 reference

2 August 2017

1 reference