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Molecular basis of resistance to thyroid hormone.
scientific article
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
12946875
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12946875%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
Molecular basis of resistance to thyroid hormone
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
12946875
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12946875%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
author
Paul M Yen
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
12946875
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12946875%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
author name string
Paul M Yen
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
12946875
retrieved
7 August 2017
publication date
1 September 2003
1 reference
stated in
Europe PubMed Central
PubMed ID
12946875
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12946875%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
published in
Trends in Endocrinology and Metabolism
1 reference
stated in
Europe PubMed Central
PubMed ID
12946875
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12946875%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
volume
14
1 reference
stated in
Europe PubMed Central
PubMed ID
12946875
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12946875%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
issue
7
1 reference
stated in
Europe PubMed Central
PubMed ID
12946875
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12946875%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
page(s)
327-333
1 reference
stated in
Europe PubMed Central
PubMed ID
12946875
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12946875%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
cites work
Familial syndrome combining deaf-mutism, stuppled epiphyses, goiter and abnormally high PBI: possible target organ refractoriness to thyroid hormone
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic and clinical features of 42 kindreds with resistance to thyroid hormone. The National Institutes of Health Prospective Study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The variable clinical phenotype in thyroid hormone resistance syndrome
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thyrotropin-induced hyperthyroidism caused by selective pituitary resistance to thyroid hormone. A new syndrome of "inappropriate secretion of TSH"
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The c-erb-A protein is a high-affinity receptor for thyroid hormone
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The c-erb-A gene encodes a thyroid hormone receptor
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear receptor coregulators: cellular and molecular biology
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Physiological and molecular basis of thyroid hormone action
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mechanism of action of thyroid hormones
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A structural role for hormone in the thyroid hormone receptor.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Spatial and temporal expression of alpha- and beta-thyroid hormone receptor mRNAs, including the beta 2-subtype, in the developing mammalian nervous system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional repression by nuclear hormone receptors
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A transcriptional co-repressor that interacts with nuclear hormone receptors
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sequence and characterization of a coactivator for the steroid hormone receptor superfamily
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Co-activators and co-repressors in the integration of transcriptional responses
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The TRAP/SMCC/Mediator complex and thyroid hormone receptor function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mediator complexes and transcription.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ordered recruitment of histone acetyltransferases and the TRAP/Mediator complex to thyroid hormone-responsive promoters in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tight linkage between the syndrome of generalized thyroid hormone resistance and the human c-erbA beta gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Generalized resistance to thyroid hormone associated with a mutation in the ligand-binding domain of the human thyroid hormone receptor beta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A base mutation of the C-erbA beta thyroid hormone receptor in a kindred with generalized thyroid hormone resistance. Molecular heterogeneity in two other kindreds
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Resistance to thyroid hormone
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Recessive inheritance of thyroid hormone resistance caused by complete deletion of the protein-coding region of the thyroid hormone receptor-beta gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential expression of thyroid hormone receptor isoforms dictates the dominant negative activity of mutant Beta receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Homozygosity for a Dominant Negative Thyroid Hormone Receptor Gene Responsible for Generalized Resistance to Thyroid Hormone*
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
New insights on the mechanism(s) of the dominant negative effect of mutant thyroid hormone receptor in generalized resistance to thyroid hormone.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Spectrum of transcriptional, dimerization, and dominant negative properties of twenty different mutant thyroid hormone beta-receptors in thyroid hormone resistance syndrome.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Divergent dimerization properties of mutant beta 1 thyroid hormone receptors are associated with different dominant negative activities
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Variable transcriptional activity and ligand binding of mutant beta 1 3,5,3'-triiodothyronine receptors from four families with generalized resistance to thyroid hormone.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A natural transactivation mutation in the thyroid hormone beta receptor: impaired interaction with putative transcriptional mediators.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel natural mutation in the thyroid hormone receptor defines a dual functional domain that exchanges nuclear receptor corepressors and coactivators.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thyroid hormone response elements differentially modulate the interactions of thyroid hormone receptors with two receptor binding domains in the steroid receptor coactivator-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lack of coactivator interaction can be a mechanism for dominant negative activity by mutant thyroid hormone receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel TR beta mutation (R383H) in resistance to thyroid hormone syndrome predominantly impairs corepressor release and negative transcriptional regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defective release of corepressor by hinge mutants of the thyroid hormone receptor found in patients with resistance to thyroid hormone.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel point mutation (R243Q) in exon 7 of the c-erbA beta thyroid hormone receptor gene in a family with resistance to thyroid hormone.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A role for helix 3 of the TRbeta ligand-binding domain in coactivator recruitment identified by characterization of a third cluster of mutations in resistance to thyroid hormone
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Five new families with resistance to thyroid hormone not caused by mutations in the thyroid hormone receptor beta gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice deficient in the steroid receptor co-activator 1 (SRC-1) are resistant to thyroid hormone
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Somatic mutation of TRbeta can cause a defect in negative regulation of TSH in a TSH-secreting pituitary tumor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transgenic mice bearing a human mutant thyroid hormone beta 1 receptor manifest thyroid function anomalies, weight reduction, and hyperactivity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functions of thyroid hormone receptors in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thyroid hormone receptors: lessons from knockout and knock-in mutant mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice with a targeted mutation in the thyroid hormone beta receptor gene exhibit impaired growth and resistance to thyroid hormone
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice with a mutation in the thyroid hormone receptor beta gene spontaneously develop thyroid carcinoma: a mouse model of thyroid carcinogenesis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An unliganded thyroid hormone receptor causes severe neurological dysfunction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A targeted dominant negative mutation of the thyroid hormone alpha 1 receptor causes increased mortality, infertility, and dwarfism in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Retardation of post-natal development caused by a negatively acting thyroid hormone receptor alpha1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Brain glucose utilization in mice with a targeted mutation in the thyroid hormone alpha or beta receptor gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2803%2900114-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1043-2760(03)00114-0
1 reference
stated in
Europe PubMed Central
PubMed ID
12946875
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12946875%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
PubMed ID
12946875
1 reference
stated in
Europe PubMed Central
PubMed ID
12946875
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12946875%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
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