(Q34480028)

2 August 2017

title

Excursions in polynuclear platinum DNA binding (English)

1 reference

2 August 2017

1 reference

John B Mangrum

1

1 reference

2 August 2017

Nicholas P Farrell

series ordinal

2

1 reference

2 August 2017

language of work or name

English

0 references

publication date

9 August 2010

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2 August 2017

published in

Chemical Communications

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2 August 2017

volume

46

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2 August 2017

issue

36

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2 August 2017

page(s)

6640-6650

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The phosphate clamp: a small and independent motif for nucleic acid backbone recognition

2 August 2017

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6 July 2018

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Structural consequences of a 3'-->3' DNA interstrand cross-link by a trinuclear platinum complex: unique formation of two such cross-links in a 10-mer duplex

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The influence of Cisplatin on the gas-phase dissociation of oligonucleotides studied by electrospray ionization tandem mass spectrometry

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A third mode of DNA binding: Phosphate clamps by a polynuclear platinum complex

6 July 2018

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Polynuclear platinum anticancer drugs are more potent than cisplatin and induce cell cycle arrest in glioma.

6 July 2018

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6 July 2018

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6 July 2018

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Synthesis, characterization, and cytotoxicity of a novel highly charged trinuclear platinum compound. Enhancement of cellular uptake with charge

6 July 2018

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Crystal structure of a junction between B-DNA and Z-DNA reveals two extruded bases

6 July 2018

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Nucleotide excision repair

6 July 2018

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Amazing stability of the arginine-phosphate electrostatic interaction

6 July 2018

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Cross-links of quadruplex structures from human telomeric DNA by dinuclear platinum complexes show the flexibility of both structures.

6 July 2018

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6 July 2018

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Unique cooperative binding interaction observed between a minor groove binding Pt antitumor agent and Hoechst dye 33258.

6 July 2018

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Nucleotide excision repair in E. coli and man.

6 July 2018

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Differential recognition by the tumor suppressor protein p53 of DNA modified by the novel antitumor trinuclear platinum drug BBR3464 and cisplatin.

6 July 2018

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Long range 1,4 and 1,6-interstrand cross-links formed by a trinuclear platinum complex. Minor groove preassociation affects kinetics and mechanism of cross-link formation as well as adduct structure.

6 July 2018

1 reference

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Preparation of interstrand cross-linked DNA oligonucleotide duplexes

6 July 2018

1 reference

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The double helix: a tale of two puckers

6 July 2018

1 reference

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Cooperative effects in long-range 1,4 DNA-DNA interstrand cross-links formed by polynuclear platinum complexes: an unexpected syn orientation of adenine bases outside the binding sites

6 July 2018

1 reference

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2.4-A crystal structure of the asymmetric platinum complex [Pt(ammine)(cyclohexylamine)]2+ bound to a dodecamer DNA duplex

6 July 2018

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DNA modifications by antitumor platinum and ruthenium compounds: their recognition and repair.

6 July 2018

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DNA and its associated processes as targets for cancer therapy

6 July 2018

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Analysis of noncovalent complexes of DNA and RNA by mass spectrometry

6 July 2018

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2.4 A crystal structure of an oxaliplatin 1,2-d(GpG) intrastrand cross-link in a DNA dodecamer duplex

6 July 2018

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Sequence specificity, conformation, and recognition by HMG1 protein of major DNA interstrand cross-links of antitumor dinuclear platinum complexes

6 July 2018

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Cellular pharmacology of polynuclear platinum anti-cancer agents

6 July 2018

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Comparison of cytotoxicity and cellular accumulation of polynuclear platinum complexes in L1210 murine leukemia cell lines

6 July 2018

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A novel charged trinuclear platinum complex effective against cisplatin-resistant tumours: hypersensitivity of p53-mutant human tumour xenografts

6 July 2018

1 reference

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Basis for recognition of cisplatin-modified DNA by high-mobility-group proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018806

Crystal structure of a double-stranded DNA containing a cisplatin interstrand cross-link at 1.63 A resolution: hydration at the platinated site

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018806

NMR solution structure of a DNA dodecamer duplex containing a cis-diammineplatinum(II) d(GpG) intrastrand cross-link, the major adduct of the anticancer drug cisplatin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018806

Diethylpyrocarbonate and osmium tetroxide as probes for drug-induced changes in DNA conformation in vitro

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018806

Cytosine-specific chemical probing of DNA using bromide and monoperoxysulfate

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018806

Solution structure of a cisplatin-induced DNA interstrand cross-link

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018806

Localized chemical reactivity in DNA associated with the sequence-specific bisintercalation of echinomycin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018806

The non-B-DNA structure of d(CA/TG)n does not differ from that of Z-DNA

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018806

A novel DNA structure induced by the anticancer bisplatinum compound crosslinked to a GpC site in DNA

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018806

Crystal structure of double-stranded DNA containing the major adduct of the anticancer drug cisplatin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018806

Crystal and molecular structure of a new Z-DNA crystal form: d[CGT(2-NH2-A)CG] and its platinated derivative

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018806

Variability in DNA minor groove width recognised by ligand binding: the crystal structure of a bis-benzimidazole compound bound to the DNA duplex d(CGCGAATTCGCG)2

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018806

Interaction of novel bis(platinum) complexes with DNA.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018806

Cytotoxicity and antitumor activity of bis(platinum) complexes. A novel class of platinum complexes active in cell lines resistant to both cisplatin and 1,2-diaminocyclohexane complexes.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018806

Characterization of cisplatin adducts of oligonucleotides by fast atom bombardment mass spectrometry.

6 July 2018

1 reference

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Arginine-mediated RNA recognition: the arginine fork.

6 July 2018

1 reference

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Anticancer activity in murine and human tumor cell lines of bis(platinum) complexes incorporating straight-chain aliphatic diamine linker groups

6 July 2018

1 reference

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Definition of a consensus binding site for p53

6 July 2018

1 reference

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DNA-binding drugs caught in action: the latest 3D pictures of drug-DNA complexes.

6 July 2018

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A study of noncovalent complexes involving single-stranded DNA and polybasic compounds using nanospray mass spectrometry.

21 January 2018

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Study of the fragmentation patterns of the phosphate-arginine noncovalent bond

27 October 2018

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Biological consequences of trinuclear platinum complexes: comparison of [[trans-PtCl(NH3)2]2mu-(trans-Pt(NH3)2(H2N(CH2)6-NH2)2)]4+ (BBR 3464) with its noncovalent congeners

27 October 2018

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ERCC1 and clinical resistance to platinum-based therapy

27 October 2018

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Structure, flexibility, and repair of two different orientations of the same alkyl interstrand DNA cross-link.

27 October 2018

1 reference

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Comparison of structural effects in 1,4 DNA-DNA interstrand cross-links formed by dinuclear and trinuclear platinum complexes

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3018806

DNA interstrand cross-links of the novel antitumor trinuclear platinum complex BBR3464. Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair

27 October 2018

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A comparison of DNA binding profiles of dinuclear platinum compounds with polyamine linkers and the trinuclear platinum phase II clinical agent BBR3464.

27 October 2018

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High-resolution footprinting studies of drug-DNA complexes using chemical and enzymatic probes

27 October 2018

1 reference

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Kinetic analysis of the stepwise formation of a long-range DNA interstrand cross-link by a dinuclear platinum antitumor complex: evidence for aquated intermediates and formation of both kinetically and thermodynamically controlled conformers

27 October 2018

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The novel trinuclear platinum complex BBR3464 induces a cellular response different from cisplatin.

27 October 2018

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Consequences of nucleic acid conformation on the binding of a trinuclear platinum drug

27 October 2018

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Studying noncovalent protein complexes by electrospray ionization mass spectrometry

27 October 2018

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Effects of geometric isomerism and ligand substitution in bifunctional dinuclear platinum complexes on binding properties and conformational changes in DNA.

27 October 2018

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The C-terminus of p53: the more you learn the less you know

27 October 2018

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12 December 2020

Deoxyribonuclease I footprinting reveals different DNA binding modes of bifunctional platinum complexes

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12 December 2020

DNA modifications by a novel bifunctional trinuclear platinum phase I anticancer agent

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12 December 2020

Kinetic and equilibria studies of the aquation of the trinuclear platinum phase II anticancer agent [(trans-PtCl(NH(3))(2))(2)(mu-trans-Pt(NH(3))(2)(NH(2)(CH(2))(6)NH(2))(2))](4+) (BBR3464)

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12 December 2020

DNA Cross-Linking Agents as Antitumor Drugs

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12 December 2020

Platination of A GG Site on Single-Stranded and Double-Stranded forms of A 14-Base Oligonucleotide with Diaqua Cisplatin followed by NMR and HPLC. Influence of the Platinum Ligands and Base Sequence on 5'-G Versus 3'-G Platination Selectivity

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12 December 2020

Structure of DNase I at 2.0 Å resolution suggests a mechanism for binding to and cutting DNA

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12 December 2020

Binding of tsHMG, a mouse testis-specific HMG-domain protein, to cisplatin-DNA adducts

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12 December 2020

Equilibrium and kinetic studies of the aquation of the dinuclear platinum complex [[trans-PtCl(NH3)2]2(mu-NH2(CH2)6NH2)]2+: pKa determinations of aqua ligands via [1H,15N] NMR spectroscopy

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12 December 2020

Tandem Mass Spectrometry of Small, Multiply Charged Oligonucleotides

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12 December 2020

The nature of the DNA template (single- versus double-stranded) affects the rate of aquation of a dinuclear Pt anticancer drug

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12 December 2020

Identifiers

DOI

10.1039/C0CC01254H

1 reference

2 August 2017

1 reference

2 August 2017

1 reference