(Q34625003)

3 August 2017

1 reference

title

DNA and its associated processes as targets for cancer therapy (English)

1 reference

3 August 2017

Laurence H Hurley

1

1 reference

PubMed ID

11990855

3 August 2017

language of work or name

English

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publication date

1 March 2002

1 reference

3 August 2017

Nature Reviews Cancer

1 reference

3 August 2017

2

1 reference

3 August 2017

3

1 reference

3 August 2017

188-200

1 reference

https://scigraph.springernature.com/pub.10.1038/nrc749

3 August 2017

0 references

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Mode of Production of Chromosome Abnormalities by the Nitrogen Mustards The Possible Role of Cross-Linking

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Glutathione S-transferases in wild-type and doxorubicin-resistant MCF-7 human breast cancer cell lines

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Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II

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Molecular struggle for transcriptional control

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Femtosecond dynamics of a drug-protein complex: daunomycin with Apo riboflavin-binding protein

31 March 2020

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Studies of the binding of actinomycin and related compounds to DNA.

31 March 2020

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Stereochemistry of actinomycin--DNA binding

31 March 2020

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Nonintercalating DNA-binding ligands: specificity of the interaction and their use as tools in biophysical, biochemical and biological investigations of the genetic material

31 March 2020

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Site-Specific Cleavage of Human Chromosome 4 Mediated by Triple-Helix Formation

31 March 2020

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Helix formation by guanylic acid

31 March 2020

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G-quadruplex DNA: a potential target for anti-cancer drug design

31 March 2020

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G-Quadruplex DNA as a target for drug design

31 March 2020

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Inhibition of human telomerase by a G-quadruplex-interactive compound

31 March 2020

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Topoisomerase I-mediated DNA damage

31 March 2020

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Investigating the biological functions of DNA topoisomerases in eukaryotic cells

31 March 2020

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INHIBITION OF CELL DIVISION IN ESCHERICHIA COLI BY ELECTROLYSIS PRODUCTS FROM A PLATINUM ELECTRODE

31 March 2020

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DNA unwinding produced by site-specific intrastrand cross-links of the antitumor drug cis-diamminedichloroplatinum(II).

31 March 2020

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Ixr1, a yeast protein that binds to platinated DNA and confers sensitivity to cisplatin.

31 March 2020

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Cisplatin-DNA adducts are molecular decoys for the ribosomal RNA transcription factor hUBF (human upstream binding factor).

31 March 2020

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Structure, Recognition, and Processing of Cisplatin-DNA Adducts.

31 March 2020

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Cooperative bending of the 21-base-pair repeats of the SV40 viral early promoter by human Sp1

31 March 2020

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Ecteinascidins 729, 743, 745, 759A, 759B, and 770: potent antitumor agents from the Caribbean tunicate Ecteinascidia turbinata

31 March 2020

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The inefficiency of incisions of ecteinascidin 743-DNA adducts by the UvrABC nuclease and the unique structural feature of the DNA adducts can be used to explain the repair-dependent toxicities of this antitumor agent

31 March 2020

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Increased DNA Binding Specificity for Antitumor Ecteinascidin 743 through Protein−DNA Interactions?

31 March 2020

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Interference of transcriptional activation by the antineoplastic drug ecteinascidin-743.

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Sequence-selective recognition and cleavage of double-helical DNA.

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Structural characterization of a 2:1 distamycin A.d(CGCAAATTGGC) complex by two-dimensional NMR.

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A Pyrrole-Imidazole Polyamide Motif for Recognition of Eleven Base Pair Sequences in the Minor Groove of DNA

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Sequence specific alkylation of DNA by hairpin pyrrole-imidazole polyamide conjugates

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Mechanisms of DNA sequence selective alkylation of guanine-N7 positions by nitrogen mustards

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Isolation and structure of a covalent cross-link adduct between mitomycin C and DNA

31 March 2020

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Peptide nucleic acids as therapeutic agents

31 March 2020

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Double duplex invasion by peptide nucleic acid: a general principle for sequence-specific targeting of double-stranded DNA.

31 March 2020

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Targeted gene knockout mediated by triple helix forming oligonucleotides

31 March 2020

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Triplex technology takes off

31 March 2020

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Design and optimization of camptothecin conjugates of triple helix-forming oligonucleotides for sequence-specific DNA cleavage by topoisomerase I.

31 March 2020

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Quadruplex structures in nucleic acids

31 March 2020

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A tetrameric DNA structure with protonated cytosine.cytosine base pairs

31 March 2020

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The beta subunit of Oxytricha telomere-binding protein promotes G-quartet formation by telomeric DNA.

31 March 2020

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The Saccharomyces cerevisiae Sgs1 helicase efficiently unwinds G-G paired DNAs

31 March 2020

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A highly selective telomerase inhibitor limiting human cancer cell proliferation

31 March 2020

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The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability

31 March 2020

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DNA tetraplex formation in the control region of c-myc

31 March 2020

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Phase I clinical and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non-Hodgkin's lymphoma

31 March 2020

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AT-rich islands in genomic DNA as a novel target for AT-specific DNA-reactive antitumor drugs

31 March 2020

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Specific gain- and loss-of-function phenotypes induced by satellite-specific DNA-binding drugs fed to Drosophila melanogaster.

31 March 2020

1 reference

How do drug-induced topoisomerase I-DNA lesions signal to the molecular interaction network that regulates cell cycle checkpoints, DNA replication, and DNA repair?

31 March 2020

1 reference

Triple helix DNA alters nucleosomal histone-DNA interactions and acts as a nucleosome barrier

31 March 2020

1 reference

Sequence-specific recognition of DNA in the nucleosome by pyrrole-imidazole polyamides

31 March 2020

1 reference

Drug interactions with nucleosomes and chromatin

31 March 2020

1 reference

Selective interactions of cationic porphyrins with G-quadruplex structures

31 March 2020

1 reference

Induction of duplex to G-quadruplex transition in the c-myc promoter region by a small molecule

31 March 2020

1 reference

Inhibition of major-groove-binding proteins by pyrrole-imidazole polyamides with an Arg-Pro-Arg positive patch

31 March 2020

1 reference

Molecular recognition of DNA by small molecules

31 March 2020

1 reference

Isolation of intercalator-dependent protein-linked DNA strand cleavage activity from cell nuclei and identification as topoisomerase II

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRC749

1 reference

PubMed ID

11990855

Dimensions Publication ID

3 August 2017

0 references

1 reference

PubMed ID

11990855