(Q31031515)

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Design and optimization of camptothecin conjugates of triple helix-forming oligonucleotides for sequence-specific DNA cleavage by topoisomerase I.

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scholarly article

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Europe PubMed Central

PubMed publication ID

28 June 2017

Design and optimization of camptothecin conjugates of triple helix-forming oligonucleotides for sequence-specific DNA cleavage by topoisomerase I. (English)

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Europe PubMed Central

PubMed publication ID

28 June 2017

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Claude Hélène

9

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Sidney M. Hecht

6

object named as

Sidney M Hecht

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Europe PubMed Central

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28 June 2017

author name string

Paola B Arimondo

1

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28 June 2017

Alexandre Boutorine

2

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28 June 2017

Brigitte Baldeyrou

3

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Europe PubMed Central

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28 June 2017

Christian Bailly

4

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28 June 2017

Masayasu Kuwahara

5

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28 June 2017

Jian-Sheng Sun

7

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28 June 2017

Thérèse Garestier

8

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28 June 2017

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publication date

27 November 2001

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28 June 2017

number of pages

9

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Journal of Biological Chemistry

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28 June 2017

277

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28 June 2017

5

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28 June 2017

3132-3140

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28 June 2017

DNA topoisomerases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110181200

21 January 2018

DNA topoisomerases: structure, function, and mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110181200

21 January 2018

Recognition and cleavage of DNA by rebeccamycin- or benzopyridoquinoxaline conjugated of triple helix-forming oligonucleotides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110181200

21 January 2018

Directing topoisomerase I mediated DNA cleavage to specific sites by camptothecin tethered to minor- and major-groove ligands

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110181200

21 January 2018

Sequence-specific trapping of topoisomerase I by DNA binding polyamide-camptothecin conjugates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110181200

21 January 2018

Stabilization of triple helical DNA by a benzopyridoquinoxaline intercalator

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110181200

21 January 2018

Rapid routes of synthesis of oligonucleotide conjugates from non-protected oligonucleotides and ligands possessing different nucleophilic or electrophilic functional groups

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110181200

21 January 2018

Chemical Modification of an Antitumor Alkaloid Camptothecin: Synthesis and Antitumor Activity of 7-C-Substituted Camptothecins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110181200

21 January 2018

Triple helix-forming oligonucleotides conjugated to indolocarbazole poisons direct topoisomerase I-mediated DNA cleavage to a specific site.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110181200

21 January 2018

Molecular modeling studies of the DNA-topoisomerase I ternary cleavable complex with camptothecin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110181200

21 January 2018

Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110181200

21 January 2018

Modulation of camptothecin analogs in the treatment of cancer: a review

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110181200

21 January 2018

Differential stabilization of eukaryotic DNA topoisomerase I cleavable complexes by camptothecin derivatives

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110181200

21 January 2018

A model for the mechanism of human topoisomerase I

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110181200

21 January 2018

Novel insights into catalytic mechanism from a crystal structure of human topoisomerase I in complex with DNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110181200

21 January 2018

A structural model for the ternary cleavable complex formed between human topoisomerase I, DNA, and camptothecin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110181200

21 January 2018

Cell death induced by topoisomerase-targeted drugs: more questions than answers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110181200

21 January 2018

Mechanism of action of eukaryotic DNA topoisomerase I and drugs targeted to the enzyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110181200

21 January 2018

Targeting topoisomerase I cleavage to specific sequences of DNA by triple helix-forming oligonucleotide conjugates. A comparison between a rebeccamycin derivative and camptothecin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110181200

21 January 2018

Oligonucleotide interactions. III. Circular dichroism studies of the conformation of deoxyoligonucleolides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110181200

21 January 2018

Identifiers

10.1074/JBC.M110181200

1 reference

Europe PubMed Central

PubMed publication ID

28 June 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 June 2017

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