(Q34480582)

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Innovative Therapies for Children with Cancer pediatric phase I study of erlotinib in brainstem glioma and relapsing/refractory brain tumors

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scholarly article

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14 January 2020

Innovative Therapies for Children with Cancer pediatric phase I study of erlotinib in brainstem glioma and relapsing/refractory brain tumors (English)

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14 January 2020

Brainstem glioma

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based on heuristic

inferred from title

Darren Hargrave

2

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14 January 2020

Fabienne Thomas

3

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14 January 2020

Felipe Andreiuolo

6

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14 January 2020

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14 January 2020

Riccardo Riccardi

9

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14 January 2020

Etienne Chatelut

11

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14 January 2020

Marie-Cécile Le Deley

12

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14 January 2020

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14 January 2020

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Isabelle Aerts

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14 January 2020

Birgit Geoerger

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Birgit Geoerger

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14 January 2020

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Didier Frappaz

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14 January 2020

author name string

Anna Ndiaye

4

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14 January 2020

Timothy Jaspan

10

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14 January 2020

Xavier Paoletti

13

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14 January 2020

Christian Saint-Rose

14

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14 January 2020

Bruce Morland

16

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14 January 2020

Jean-Claude Gentet

17

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14 January 2020

Valérie Méresse

18

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14 January 2020

Gilles Vassal

19

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14 January 2020

ITCC (Innovative Therapies for Children with Cancer) European Consortium

20

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14 January 2020

publication date

25 October 2010

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14 January 2020

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14 January 2020

13

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14 January 2020

1

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14 January 2020

109-118

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14 January 2020

EGFRvIII deletion mutations in pediatric high-grade glioma and response to targeted therapy in pediatric glioma cell lines

1 reference

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6 July 2018

Epidermal growth factor receptor pathway gene expressions and biological response of glioblastoma multiforme cell lines to erlotinib.

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6 July 2018

Phase I and pharmacokinetic studies of erlotinib administered concurrently with radiotherapy for children, adolescents, and young adults with high-grade glioma.

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6 July 2018

Phase II study of erlotinib plus temozolomide during and after radiation therapy in patients with newly diagnosed glioblastoma multiforme or gliosarcoma

1 reference

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6 July 2018

Phase I/II trial of erlotinib and temozolomide with radiation therapy in the treatment of newly diagnosed glioblastoma multiforme: North Central Cancer Treatment Group Study N0177.

1 reference

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6 July 2018

Chemotherapy for malignant brain tumors of childhood.

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6 July 2018

Pediatric phase I and pharmacokinetic study of erlotinib followed by the combination of erlotinib and temozolomide: a Children's Oncology Group Phase I Consortium Study

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6 July 2018

Phase II study of carboplatin and erlotinib (Tarceva, OSI-774) in patients with recurrent glioblastoma

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6 July 2018

Protein expression of platelet-derived growth factor receptor correlates with malignant histology and PTEN with survival in childhood gliomas

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6 July 2018

An interdisciplinary consensus on managing skin reactions associated with human epidermal growth factor receptor inhibitors.

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6 July 2018

Recent development in chemotherapy of paediatric brain tumours

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6 July 2018

Pediatric CNS tumors: current treatment and future directions.

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6 July 2018

Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group

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6 July 2018

Phase I trial of imatinib in children with newly diagnosed brainstem and recurrent malignant gliomas: a Pediatric Brain Tumor Consortium report

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6 July 2018

Mammalian target of rapamycin inhibition promotes response to epidermal growth factor receptor kinase inhibitors in PTEN-deficient and PTEN-intact glioblastoma cells

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6 July 2018

Diffuse brainstem glioma in children: critical review of clinical trials

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6 July 2018

Intratumoral hemorrhage among children with newly diagnosed, diffuse brainstem glioma

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6 July 2018

Phase 1 study of erlotinib HCl alone and combined with temozolomide in patients with stable or recurrent malignant glioma

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6 July 2018

A review of erlotinib and its clinical use.

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6 July 2018

Erlotinib in previously treated non-small-cell lung cancer

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6 July 2018

Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer

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6 July 2018

Combination treatment of glioblastoma multiforme cell lines with the anti-malarial artesunate and the epidermal growth factor receptor tyrosine kinase inhibitor OSI-774.

1 reference

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6 July 2018

Inverse correlation of epidermal growth factor receptor messenger RNA induction and suppression of anchorage-independent growth by OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in glioblastoma multiforme cell lines

1 reference

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6 July 2018

ERBB1 is amplified and overexpressed in high-grade diffusely infiltrative pediatric brain stem glioma

1 reference

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6 July 2018

Overexpression of the EGFR/FKBP12/HIF-2alpha pathway identified in childhood astrocytomas by angiogenesis gene profiling

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6 July 2018

ERBB receptor signaling promotes ependymoma cell proliferation and represents a potential novel therapeutic target for this disease.

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6 July 2018

Preferential inactivation of the p53 tumor suppressor pathway and lack of EGFR amplification distinguish de novo high grade pediatric astrocytomas from de novo adult astrocytomas

1 reference

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6 July 2018

Epidermal growth factor receptor expression and gene amplification in high-grade non-brainstem gliomas of childhood

1 reference

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6 July 2018

Conduct of phase I trials in children with cancer

1 reference

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6 July 2018

Childhood cancer survival in Europe: an overview.

1 reference

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21 January 2018

Phase I trial of erlotinib with radiation therapy in patients with glioblastoma multiforme: results of North Central Cancer Treatment Group protocol N0177.

1 reference

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21 January 2018

Identification of molecular characteristics correlated with glioblastoma sensitivity to EGFR kinase inhibition through use of an intracranial xenograft test panel

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21 January 2018

EGFR tyrosine kinase inhibition radiosensitizes and induces apoptosis in malignant glioma and childhood ependymoma xenografts

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21 January 2018

The plasma and cerebrospinal fluid pharmacokinetics of erlotinib and its active metabolite (OSI-420) after intravenous administration of erlotinib in non-human primates.

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21 January 2018

Plasma and cerebrospinal fluid pharmacokinetics of erlotinib and its active metabolite OSI-420.

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21 January 2018

Continual reassessment method: a likelihood approach.

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21 January 2018

Specific method for determination of OSI-774 and its metabolite OSI-420 in human plasma by using liquid chromatography-tandem mass spectrometry

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21 January 2018

Population pharmacokinetics of erlotinib and its pharmacokinetic/pharmacodynamic relationships in head and neck squamous cell carcinoma.

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21 January 2018

Activation of STAT3, MAPK, and AKT in malignant astrocytic gliomas: correlation with EGFR status, tumor grade, and survival.

1 reference

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21 January 2018

Phase I and pharmacokinetic study of gefitinib in children with refractory solid tumors: a Children's Oncology Group Study

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21 January 2018

Prospective study of awake craniotomy used routinely and nonselectively for supratentorial tumors.

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21 January 2018

Clinical utility of fluorescence in situ hybridization (FISH) in morphologically ambiguous gliomas with hybrid oligodendroglial/astrocytic features.

1 reference

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21 January 2018

Stereotactic biopsy of diffuse pontine lesions in children.

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27 October 2018

Rarity of PTEN deletions and EGFR amplification in malignant gliomas of childhood: results from the Children's Cancer Group 945 cohort.

1 reference

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27 October 2018

Brainstem stereotactic biopsy sampling in children.

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27 October 2018

Identifiers

10.1093/NEUONC/NOQ141

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14 January 2020

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Europe PubMed Central

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14 January 2020

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Europe PubMed Central

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14 January 2020

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