(Q34481059)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26082496%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

title

Development of an intein-mediated split-Cas9 system for gene therapy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26082496%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

0 references

0 references

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26082496%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Stefan Engelhardt

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26082496%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

6

Wolfgang Wurst

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26082496%20AND%20SRC:MED&resulttype=core&format=json

Dong‐Jiunn Jeffery Truong

17 February 2020

1

object named as

Dong-Jiunn Jeffery Truong

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26082496%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

7

Oskar Ortiz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26082496%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

author name string

Karin Kühner

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26082496%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Stanislas Werfel

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26082496%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

language of work or name

English

0 references

publication date

16 June 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26082496%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

published in

Nucleic Acids Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26082496%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

volume

43

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26082496%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

issue

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26082496%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

page(s)

6450-6458

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26082496%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

17 February 2020

copyright license

start time

7 November 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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1 reference

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In vivo genome editing using Staphylococcus aureus Cas9

6 July 2018

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Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells.

6 July 2018

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Rational design of a split-Cas9 enzyme complex

6 July 2018

1 reference

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Creation of targeted genomic deletions using TALEN or CRISPR/Cas nuclease pairs in one-cell mouse embryos.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4513872

A split-Cas9 architecture for inducible genome editing and transcription modulation

6 July 2018

1 reference

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Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9

6 July 2018

1 reference

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Programmable RNA recognition and cleavage by CRISPR/Cas9.

6 July 2018

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A split intein T7 RNA polymerase for transcriptional AND-logic.

6 July 2018

1 reference

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CRISPR/Cas9-mediated genome engineering: an adeno-associated viral (AAV) vector toolbox

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4513872

Adeno-associated virus: fit to serve

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4513872

Cell-Mediated Immunity to AAV Vectors, Evolving Concepts and Potential Solutions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4513872

Rapid and highly efficient inducible cardiac gene knockout in adult mice using AAV-mediated expression of Cre recombinase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4513872

Permanent alteration of PCSK9 with in vivo CRISPR-Cas9 genome editing

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4513872

Principles of genetic circuit design

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4513872

Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype.

6 July 2018

1 reference

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Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4513872

Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4513872

Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4513872

Orthogonal Cas9 proteins for RNA-guided gene regulation and editing

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4513872

Two- and three-input TALE-based AND logic computation in embryonic stem cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4513872

Highly efficient targeted mutagenesis in mice using TALENs

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4513872

Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4513872

Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4513872

Optical control of mammalian endogenous transcription and epigenetic states

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4513872

CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4513872

Circular permutation prediction reveals a viable backbone disconnection for split proteins: an approach in identifying a new functional split intein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4513872

Post-translational tools expand the scope of synthetic biology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4513872

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4513872

Modeling disease mutations by gene targeting in one-cell mouse embryos

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4513872

FLASH assembly of TALENs for high-throughput genome editing

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4513872

Kinetic control of one-pot trans-splicing reactions by using a wild-type and designed split intein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4513872

Optimizing promoters for recombinant adeno-associated virus-mediated gene expression in the peripheral and central nervous system using self-complementary vectors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4513872

Adenoviral vector immunity: its implications and circumvention strategies

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4513872

Split-CreERT2: temporal control of DNA recombination mediated by split-Cre protein fragment complementation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4513872

Protein trans-splicing as a means for viral vector-mediated in vivo gene therapy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4513872

Disruption of overlapping transcripts in the ROSA beta geo 26 gene trap strain leads to widespread expression of beta-galactosidase in mouse embryos and hematopoietic cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4513872

Theory for the folding and stability of globular proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4513872

Reversible and tissue-specific activation of MAP kinase signaling by tamoxifen in Braf(V637)ER(T2) mice.

6 July 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKV601

Faster protein splicing with the Nostoc punctiforme DnaE intein using non-native extein residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKV601

Post-translational enzyme activation in an animal via optimized conditional protein splicing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKV601

Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKV601

Protein splicing triggered by a small molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKV601

Activation of protein splicing with light in yeast

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26082496

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKV601

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26082496%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26082496%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

PubMed publication ID

26082496

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26082496%20AND%20SRC:MED&resulttype=core&format=json