(Q34481778)

2 August 2017

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title

Neuroprotection for Parkinson's disease: a new approach for a new millennium (English)

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2 August 2017

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Drukarch B

1

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2 August 2017

van Muiswinkel FL

series ordinal

2

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2 August 2017

language of work or name

English

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publication date

1 October 2001

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Expert Opinion on Investigational Drugs

2 August 2017

published in

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2 August 2017

volume

10

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2 August 2017

issue

10

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2 August 2017

page(s)

1855-1868

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Etiology and pathogenesis of Parkinson's disease

2 August 2017

cites work

1 reference

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Chronic systemic pesticide exposure reproduces features of Parkinson's disease

21 January 2018

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Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease

21 January 2018

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Distribution of noradrenaline and dopamine (3-hydroxytyramine) in the human brain and their behavior in diseases of the extrapyramidal system

21 January 2018

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Therapeutic advances in idiopathic Parkinsonism.

21 January 2018

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Success and problems of long-term levodopa therapy in Parkinson's disease

21 January 2018

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Apoptosis modulators in the therapy of neurodegenerative diseases

21 January 2018

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Remacemide: current status and clinical applications

21 January 2018

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The oxidant stress hypothesis in Parkinson's disease: evidence supporting it

21 January 2018

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Parkinson's disease: a major hypokinetic basal ganglia disorder

21 January 2018

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Parkinson's disease: prospects for improved drug therapy

21 January 2018

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Rasagiline [N-propargyl-1R(+)-aminoindan], a selective and potent inhibitor of mitochondrial monoamine oxidase B

21 January 2018

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Cytotoxic and genotoxic potential of dopamine

21 January 2018

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Tyrosinase mRNA is expressed in human substantia nigra.

21 January 2018

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Biochemical and toxicological properties of the oxidation products of catecholamines

21 January 2018

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The oxidative metabolism of catecholamines in the brain: a review

21 January 2018

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Biosynthesis, structure, and function of neuromelanin and its relation to Parkinson's disease: a critical update

21 January 2018

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The neuromelanin of the human substantia nigra.

21 January 2018

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Neuromelanin biosynthesis is driven by excess cytosolic catecholamines not accumulated by synaptic vesicles.

21 January 2018

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Protection of intracellular dopamine cytotoxicity by dopamine disposition and metabolism factors

21 January 2018

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Low numbers and no loss of melanized nigral neurons with increasing age in normal human brains from India.

21 January 2018

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21 January 2018

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NADPH cytochrome P-450 reductase in rat, mouse and human brain

21 January 2018

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Overview of enzymes of drug metabolism

21 January 2018

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Detoxication enzymes and chemoprevention

21 January 2018

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Antioxidant and prooxidant functions of DT-diaphorase in quinone metabolism

21 January 2018

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Preferential expression of superoxide dismutase messenger RNA in melanized neurons in human mesencephalon.

21 January 2018

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Glutathione transferases catalyse the detoxication of oxidized metabolites (o-quinones) of catecholamines and may serve as an antioxidant system preventing degenerative cellular processes

21 January 2018

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Chemical and molecular regulation of enzymes that detoxify carcinogens

21 January 2018

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On the mechanisms of induction of cancer-protective enzymes: a unifying proposal

21 January 2018

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Chemoprotective 3H-1,2-dithiole-3-thione induces antioxidant genes in vivo.

21 January 2018

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Reactive oxygen species-related induction of multidrug resistance-associated protein 2 expression in primary hepatocytes exposed to sulforaphane

21 January 2018

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Aryl hydrocarbon receptor-mediated signal transduction

21 January 2018

1 reference

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Potency of Michael reaction acceptors as inducers of enzymes that protect against carcinogenesis depends on their reactivity with sulfhydryl groups

21 January 2018

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The potency of inducers of NAD(P)H:(quinone-acceptor) oxidoreductase parallels their efficiency as substrates for glutathione transferases. Structural and electronic correlations

21 January 2018

1 reference

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Identification of a common chemical signal regulating the induction of enzymes that protect against chemical carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1855

Redox regulation of genes that protect against carcinogens

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.10.10.1855

Antioxidant response element

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1855

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1855

Regulation of the antioxidant response element by protein kinase C-mediated phosphorylation of NF-E2-related factor 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1855

Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1855

Signal transduction events elicited by natural products: role of MAPK and caspase pathways in homeostatic response and induction of apoptosis.

21 January 2018

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Chemoprevention: increased potential to bear fruit

21 January 2018

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The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1855

An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1855

Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1855

Astrocyte-mediated enhancement of neuronal survival is abolished by glutathione deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1855

Astrocyte-enhanced neuronal survival is mediated by scavenging of extracellular reactive oxygen species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1855

Anethole dithiolethione: biochemical considerations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1855

Metabolism of xenobiotics in the central nervous system: implications and challenges.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1855

Nuclear factor kappa B is a molecular target for sulforaphane-mediated anti-inflammatory mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1855

Inhibition of NF-kappa B activation in human T-cell lines by anetholdithiolthione

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1855

10.1517/13543784.10.10.1855

21 January 2018

Identifiers

DOI

1 reference

2 August 2017

1 reference