(Q34481881)

2 August 2017

1 reference

title

Protein kinase C inhibitors as novel anticancer drugs (English)

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2 August 2017

Goekjian PG

1

1 reference

2 August 2017

Jirousek MR

series ordinal

2

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2 August 2017

language of work or name

English

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publication date

1 December 2001

1 reference

Expert Opinion on Investigational Drugs

2 August 2017

published in

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2 August 2017

volume

10

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2 August 2017

issue

12

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2 August 2017

page(s)

2117-2140

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The extended protein kinase C superfamily

2 August 2017

cites work

1 reference

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Cell-cycle dysregulation and the molecular mechanisms of prostate cancer

21 January 2018

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Role of telomerase in normal and cancer cells

21 January 2018

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Angiogenesis in cancer and other diseases

21 January 2018

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Biological mechanisms in breast cancer invasiveness: relevance to preventive interventions

21 January 2018

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Protein kinase C targeting in antineoplastic treatment strategies

21 January 2018

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Protein kinase C-mediated regulation of the cell cycle

21 January 2018

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Connecting signaling and cell cycle progression in growth factor-stimulated cells

21 January 2018

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Protein kinase C: a paradigm for regulation of protein function by two membrane-targeting modules

21 January 2018

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Multiple pathways control protein kinase C phosphorylation

21 January 2018

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Insulin-activated protein kinase Cbeta bypasses Ras and stimulates mitogen-activated protein kinase activity and cell proliferation in muscle cells.

21 January 2018

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Selective inhibition of rat mesangial cell proliferation by a synthetic peptide derived from the sequence of the C2 region of PKCbeta

21 January 2018

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Growth hormone and phorbol esters require specific protein kinase C isoforms to activate mitogen-activated protein kinases in 3T3-F442A cells

21 January 2018

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Antisense inhibition of protein kinase Calpha reverses the transformed phenotype in human lung carcinoma cells

21 January 2018

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AP-1: one switch for many signals

21 January 2018

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Stable transfection of protein kinase C alpha cDNA in hormone-dependent breast cancer cell lines

21 January 2018

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Activation of Protein Kinase-C Inhibits Vitamin D Receptor Gene Expression

21 January 2018

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Involvement of p21(Waf1/Cip1) in protein kinase C alpha-induced cell cycle progression

21 January 2018

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Increased and altered DNA binding of human p53 by S and G2/M but not Gl cyclin-dependent kinases

21 January 2018

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Serine/threonine protein kinases and apoptosis.

21 January 2018

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Differential sensitivity of breast cancer cells to tumor necrosis factor-alpha: involvement of protein kinase C.

21 January 2018

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Overexpression of protein kinase C-beta1 isoenzyme suppresses indomethacin-induced apoptosis in gastric epithelial cells

21 January 2018

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Protein kinase C-alpha is essential for Ramos-BL B cell survival.

21 January 2018

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Apoptosis is induced in glioma cells by antisense oligonucleotides to protein kinase C alpha and is enhanced by cycloheximide

21 January 2018

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Atypical protein kinase C iota protects human leukemia cells against drug-induced apoptosis

21 January 2018

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Protein complexes activate distinct caspase cascades in death receptor and stress-induced apoptosis

21 January 2018

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PED/PEA-15: an anti-apoptotic molecule that regulates FAS/TNFR1-induced apoptosis

21 January 2018

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Involvement of protein kinase C-beta and ceramide in tumor necrosis factor-alpha-induced but not Fas-induced apoptosis of human myeloid leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.12.2117

Different roles of protein kinase C alpha and delta isoforms in the regulation of neutral sphingomyelinase activity in HL-60 cells

21 January 2018

1 reference

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Subtype-specific translocation of the delta subtype of protein kinase C and its activation by tyrosine phosphorylation induced by ceramide in HeLa cells

21 January 2018

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N-acylated serinol is a novel ceramide mimic inducing apoptosis in neuroblastoma cells

21 January 2018

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Ceramide directly activates protein kinase C zeta to regulate a stress-activated protein kinase signaling complex

21 January 2018

1 reference

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Ceramide-dependent regulation of p42/p44 mitogen-activated protein kinase and c-Jun N-terminal-directed protein kinase in cultured airway smooth muscle cells

21 January 2018

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p90(RSK) blocks bad-mediated cell death via a protein kinase C-dependent pathway

21 January 2018

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Ribozyme inhibition of the protein kinase C alpha triggers apoptosis in glioma cells

21 January 2018

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Critical targets of protein kinase C in differentiation of tumour cells.

21 January 2018

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Signaling via vascular endothelial growth factor receptors

21 January 2018

1 reference

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The proliferative effect of vascular endothelial growth factor requires protein kinase C-alpha and protein kinase C-zeta

21 January 2018

1 reference

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Role of protein kinase C isoforms in phorbol ester-induced vascular endothelial growth factor expression in human glioblastoma cells.

21 January 2018

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Eicosanoid activation of extracellular signal-regulated kinase1/2 in human epidermoid carcinoma cells

21 January 2018

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Mechanism of inhibition of P-glycoprotein-mediated drug transport by protein kinase C blockers

21 January 2018

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Protein kinase C in human renal cell carcinomas: role in invasion and differential isoenzyme expression

21 January 2018

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The role of protein kinase Calpha in U-87 glioma invasion.

21 January 2018

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Human melanoma metastasis is inhibited following ex vivo treatment with an antisense oligonucleotide to protein kinase C-alpha

21 January 2018

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Integrins as signaling molecules and targets for tumor therapy

21 January 2018

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Specificity and mechanism of action of some commonly used protein kinase inhibitors

21 January 2018

1 reference

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Differential inhibition of cytosolic and membrane-derived protein kinase C activity by staurosporine and other kinase inhibitors

21 January 2018

1 reference

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A derivative of staurosporine (CGP 41 251) shows selectivity for protein kinase C inhibition and in vitro anti-proliferative as well as in vivo anti-tumor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.12.2117

Comparison of ability of protein kinase C inhibitors to arrest cell growth and to alter cellular protein kinase C localisation

21 January 2018

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Blocking of glioma proliferation in vitro and in vivo and potentiating the effects of BCNU and cisplatin: UCN-01, a selective protein kinase C inhibitor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.12.2117

Activation of protein kinase C subtypes alpha, gamma, delta, epsilon, zeta, and eta by tumor-promoting and nontumor-promoting agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.12.2117

Chemistry and clinical biology of the bryostatins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.12.2117

Beta2-chimaerin is a high affinity receptor for the phorbol ester tumor promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.12.2117

CRC/EORTC/NCI Joint Formulation Working Party: experiences in the formulation of investigational cytotoxic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.12.2117

A phase II trial of bryostatin 1 in patients with non-Hodgkin's lymphoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.12.2117

Partial Inhibition of Multidrug Resistance by Safingol Is Independent of Modulation of P-glycoprotein Substrate Activities and Correlated with Inhibition of Protein Kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.12.2117

Phase I trial of ilmofosine as a 24 hour infusion weekly

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.12.2117

Up-regulation of p21WAF1 expression in myeloid cells is activated by the protein kinase C pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.12.2117

Characterization of apoptosis induced by protein kinase C inhibitors and its modulation by the caspase pathway in acute promyelocytic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.12.2117

Inhibition of protein kinase C-alpha isoform enhances the P-glycoprotein expression and the survival of LoVo human colon adenocarcinoma cells to doxorubicin exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.12.2117

Antisense oligonucleotides as therapeutic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.12.2117

Intracellular mRNA cleavage induced through activation of RNase P by nuclease-resistant external guide sequences.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.12.2117

Identification of PKC-isoform-specific biological actions using pharmacological approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.12.2117

Enzymatic rationale and preclinical support for a potent protein kinase C beta inhibitor in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.12.2117

Protein kinase C activation: isozyme-specific effects on metabolism and cardiovascular complications in diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.12.2117

The therapeutic potential of targeting the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.12.2117

Bryostatin 1 induces biphasic activation of protein kinase D in intact cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.12.2117

Enantioselective synthesis and antiproliferative properties of an ilmofosine analog, 2'-(trimethylammonio)ethyl 3-(hexadecyloxy)-2-(methoxymethyl)propyl phosphate, on epithelial cancer cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.12.2117

Gö 6976, a selective inhibitor of protein kinase C, is a potent antagonist of human immunodeficiency virus 1 induction from latent/low-level-producing reservoir cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.12.2117

Gö 6976 is a potent inhibitor of neurotrophin-receptor intrinsic tyrosine kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.12.2117

10.1517/13543784.10.12.2117

21 January 2018

Identifiers

DOI

1 reference

2 August 2017

1 reference