(Q34482095)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9838074%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

review article

1 reference

title

Diacylglycerol--when is it an intracellular messenger? (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9838074%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9838074%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

author name string

M J Wakelam

series ordinal

1

1 reference

2 August 2017

language of work or name

English

0 references

publication date

1 December 1998

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9838074%20AND%20SRC:MED&resulttype=core&format=json

Biochimica et Biophysica Acta

7 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9838074%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

volume

1436

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9838074%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

issue

1-2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9838074%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

page(s)

117-126

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9838074%20AND%20SRC:MED&resulttype=core&format=json

Regulation of the biosynthesis of triacylglycerol, phosphatidylcholine and phosphatidylethanolamine in the liver

7 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C

7 January 2021

1 reference

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Inositol phosphates and cell signalling

7 January 2021

1 reference

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Mass measurement of inositol 1,4,5-trisphosphate and sn-1,2-diacylglycerol in bombesin-stimulated Swiss 3T3 mouse fibroblasts.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Stimulation of phosphatidylcholine breakdown and diacylglycerol production by growth factors in Swiss-3T3 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Interleukin 3 stimulates phosphatidylcholine turnover in a mast/megakaryocyte cell line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Stimulation of the hydrolysis of phosphatidylinositol 4,5-bisphosphate and phosphatidylcholine by endothelin, a complete mitogen for Rat-1 fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Phosphatidylcholine breakdown and signal transduction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Analysis of the water-soluble products of phosphatidylcholine breakdown by ion-exchange chromatography. Bombesin and TPA (12-O-tetradecanoylphorbol 13-acetate) stimulate choline generation in Swiss 3T3 cells by a common mechanism

7 January 2021

1 reference

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Stimulated phosphatidylcholine hydrolysis as a signal transduction pathway in mitogenesis.

7 January 2021

1 reference

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Vasopressin-stimulated [3H]-inositol phosphate and [3H]-phosphatidylbutanol accumulation in A10 vascular smooth muscle cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Multiple sources of sn-1,2-diacylglycerol in platelet-derived-growth-factor-stimulated Swiss 3T3 fibroblasts. Evidence for activation of phosphoinositidase C and phosphatidylcholine-specific phospholipase D.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Carbachol stimulates a different phospholipid metabolism than nerve growth factor and basic fibroblast growth factor in PC12 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Bombesin stimulates distinct time-dependent changes in the sn-1,2-diradylglycerol molecular species profile from Swiss 3T3 fibroblasts as analysed by 3,5-dinitrobenzoyl derivatization and h.p.l.c. separation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Epidermal growth factor stimulates distinct diradylglycerol species generation in Swiss 3T3 fibroblasts: evidence for a potential phosphatidylcholine-specific phospholipase C-catalysed pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Diradylglycerol formation in cholecystokinin-stimulated rabbit pancreatic acini. Assessment of precursor phospholipids by means of molecular species analysis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Phospholipase C-mediated hydrolysis of phosphatidylcholine is an important step in PDGF-stimulated DNA synthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Utilization of phosphatidylcholine and production of diradylglycerol as a consequence of sphingomyelin synthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

TNF activates NF-kappa B by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

NIH 3T3 cells stably transfected with the gene encoding phosphatidylcholine-hydrolyzing phospholipase C from Bacillus cereus acquire a transformed phenotype

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Ceramide-induced translocation of protein kinase C-delta and -epsilon to the cytosol. Implications in apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Ceramide inactivates cellular protein kinase Calpha

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Activation of the sphingomyelin cycle through the low-affinity neurotrophin receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Functions of ceramide in coordinating cellular responses to stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

The co-mitogenic combination of transforming growth factor beta 1 and bombesin protects protein kinase C-delta from late-phase down-regulation, despite synergy in diacylglycerol accumulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Sphingomyelin synthase, a potential regulator of intracellular levels of ceramide and diacylglycerol during SV40 transformation. Does sphingomyelin synthase account for the putative phosphatidylcholine-specific phospholipase C?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Phosphatidate phosphohydrolase and signal transduction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Inhibition of the metabolism of phosphatidylethanol and phosphatidic acid, and stimulation of insulin release, by propranolol in intact pancreatic islets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Rapid desensitization of vasopressin-stimulated phosphatidylinositol 4,5-bisphosphate and phosphatidylcholine hydrolysis questions the role of these pathways in sustained diacylglycerol formation in A10 vascular-smooth-muscle cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

The regulation of phospholipase D activity and its role in sn-1,2-diradylglycerol formation in bombesin- and phorbol 12-myristate 13-acetate-stimulated Swiss 3T3 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Epidermal growth factor increases sn-1,2-diacylglycerol levels and activates phospholipase D-catalysed phosphatidylcholine breakdown in Swiss 3T3 cells in the absence of inositol-lipid hydrolysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Diacylglycerol and phosphatidate generated by phospholipases C and D, respectively, have distinct fatty acid compositions and functions. Phospholipase D-derived diacylglycerol does not activate protein kinase C in porcine aortic endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

The molecular selectivity of phospholipase D in HL60 granulocytes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Molecular species analysis of 1,2-diacylglycerols and phosphatidic acid formed during bombesin stimulation of Swiss 3T3 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Time-course changes in content and fatty acid composition of phosphatidic acid from rat thymocytes during concanavalin A stimulation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Identification and cDNA cloning of 35-kDa phosphatidic acid phosphatase (type 2) bound to plasma membranes. Polymerase chain reaction amplification of mouse H2O2-inducible hic53 clone yielded the cDNA encoding phosphatidic acid phosphatase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Cloning and characterization of two human isozymes of Mg2+-independent phosphatidic acid phosphatase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Porcine diacylglycerol kinase sequence has zinc finger and E-F hand motifs.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Cloning of a novel human diacylglycerol kinase (DGKtheta) containing three cysteine-rich domains, a proline-rich region, and a pleckstrin homology domain with an overlapping Ras-associating domain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Arachidonoyl-diacylglycerol kinase. Specific in vitro inhibition by polyphosphoinositides suggests a mechanism for regulation of phosphatidylinositol biosynthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Molecular cloning of a novel human diacylglycerol kinase highly selective for arachidonate-containing substrates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Purification and characterization of sn-1-stearoyl-2-arachidonoylglycerol kinase from pig testes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Molecular cloning of a novel diacylglycerol kinase isozyme with a pleckstrin homology domain and a C-terminal tail similar to those of the EPH family of protein-tyrosine kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Cloning and characterization of a glucocorticoid-induced diacylglycerol kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Molecular cloning and characterization of a novel human diacylglycerol kinase zeta

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Acyl chain dependence of diacylglycerol activation of protein kinase C activity in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Synergistic activation of protein kinase C by arachidonic acid and diacylglycerols in vitro: generation of a stable membrane-bound, cofactor-independent state of protein kinase C activity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

The regulation and cellular functions of phosphatidylcholine hydrolysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Stimulation of actin stress fibre formation mediated by activation of phospholipase D

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Activation of actin polymerization by phosphatidic acid derived from phosphatidylcholine in IIC9 fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

ADP-ribosylation-factor-regulated phospholipase D activity localizes to secretory vesicles and mobilizes to the plasma membrane following N-formylmethionyl-leucyl-phenylalanine stimulation of human neutrophils.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Phospholipase D1 localises to secretory granules and lysosomes and is plasma-membrane translocated on cellular stimulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Phosphatidic acid-mediated phosphorylation of the NADPH oxidase component p47-phox. Evidence that phosphatidic acid may activate a novel protein kinase.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Raf-1 kinase possesses distinct binding domains for phosphatidylserine and phosphatidic acid. Phosphatidic acid regulates the translocation of Raf-1 in 12-O-tetradecanoylphorbol-13-acetate-stimulated Madin-Darby canine kidney cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Distinct phospholipase C-regulated signalling pathways in Swiss 3T3 fibroblasts induce the rapid generation of the same polyunsaturated diacylglycerols.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Diacylglycerols and phosphatidates: which molecular species are intracellular messengers?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Localization of protein kinases by anchoring proteins: a theme in signal transduction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Signaling through scaffold, anchoring, and adaptor proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Protein kinase C and phospholipase C: bilayer interactions and regulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Nuclear translocation of RhoA mediates the mitogen-induced activation of phospholipase D involved in nuclear envelope signal transduction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Phospholipase D is present on Golgi-enriched membranes and its activation by ADP ribosylation factor is sensitive to brefeldin A

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Phosphatidic acid formation by phospholipase D is required for transport from the endoplasmic reticulum to the Golgi complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Alpha-thrombin-induced nuclear sn-1,2-diacylglycerols are derived from phosphatidylcholine hydrolysis in cultured fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Phosphatidic acid generation through interleukin 2 (IL-2)-induced alpha-diacylglycerol kinase activation is an essential step in IL-2-mediated lymphocyte proliferation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Diacylglycerol kinase is phosphorylated in vivo upon stimulation of the epidermal growth factor receptor and serine/threonine kinases, including protein kinase C-epsilon

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Hydrolysis of phosphatidylcholine is stimulated by Ras proteins during mitogenic signal transduction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Ras mediates the activation of phospholipase D by v-Src

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Increased concentrations of phosphatidate, diacylglycerol and ceramide in ras- and tyrosine kinase (fps)-transformed fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Normal p21N-ras couples bombesin and other growth factor receptors to inositol phosphate production

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Progesterone but not ras requires MPF for in vivo activation of MAPK and S6 KII: MAPK is an essential conexion point of both signaling pathways.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Hepatic protein kinase C is not activated despite high intracellular 1,2-sn-diacylglycerol in obese Zucker rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Molecular cloning and expression of a 90-kDa diacylglycerol kinase that predominantly localizes in neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

Regulation of eukaryotic phospholipid metabolism 1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2760%2898%2900123-4

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0005-2760(98)00123-4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9838074%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

1 reference