(Q34484605)

2 August 2017

Unraveling CRISPR-Cas9 genome engineering parameters via a library-on-library approach (English)

1 reference

2 August 2017

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George M Church

4

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author name string

Raj Chari

series ordinal

1

1 reference

2 August 2017

Prashant Mali

series ordinal

2

1 reference

2 August 2017

Mark Moosburner

series ordinal

3

1 reference

2 August 2017

13 July 2015

1 reference

2 August 2017

1 reference

2 August 2017

12

1 reference

2 August 2017

9

1 reference

2 August 2017

823-826

1 reference

https://scigraph.springernature.com/pub.10.1038/nmeth.3473

2 August 2017

0 references

cites work

GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5292764

Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5292764

Efficient mutagenesis by Cas9 protein-mediated oligonucleotide insertion and large-scale assessment of single-guide RNAs

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5292764

Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5292764

Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5292764

Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5292764

Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5292764

Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5292764

The UCSC Genome Browser database: 2014 update

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5292764

Orthogonal Cas9 proteins for RNA-guided gene regulation and editing

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5292764

Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5292764

High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5292764

CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5292764

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5292764

RNA-guided human genome engineering via Cas9

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5292764

Multiplex genome engineering using CRISPR/Cas systems

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5292764

An integrated encyclopedia of DNA elements in the human genome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5292764

Coupling endonucleases with DNA end-processing enzymes to drive gene disruption

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5292764

FLASH: fast length adjustment of short reads to improve genome assemblies

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5292764

BigWig and BigBed: enabling browsing of large distributed datasets

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5292764

Design of 240,000 orthogonal 25mer DNA barcode probes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5292764

SeqMap: mapping massive amount of oligonucleotides to the genome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5292764

The landscape of histone modifications across 1% of the human genome in five human cell lines

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5292764

A census of human cancer genes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5292764

The UCSC Table Browser data retrieval tool

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5292764

Fast and accurate short read alignment with Burrows-Wheeler transform

6 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNMETH.3473

The Sequence Alignment/Map format and SAMtools

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNMETH.3473

Preserving genome integrity: the DdrA protein of Deinococcus radiodurans R1

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNMETH.3473

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NMETH.3473

1 reference

Dimensions Publication ID

2 August 2017

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1 reference

2 August 2017

1 reference