(Q34486506)

2 August 2017

title

Increased risk of vincristine neurotoxicity associated with low CYP3A5 expression genotype in children with acute lymphoblastic leukemia (English)

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2 August 2017

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lymphoblastic leukemia

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10

Jamie L Renbarger

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2 August 2017

Akinbode Egbelakin

1

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2 August 2017

Michael J Ferguson

2

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2 August 2017

Emily A MacGill

3

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2 August 2017

Amalia S Lehmann

4

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2 August 2017

Ariel R Topletz

5

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2 August 2017

Sara K Quinney

6

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2 August 2017

Lang Li

7

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2 August 2017

Kevin C McCammack

8

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2 August 2017

Stephen D Hall

9

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2 August 2017

publication date

11 November 2010

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2 August 2017

published in

Pediatric Blood & Cancer

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2 August 2017

volume

56

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2 August 2017

issue

3

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2 August 2017

page(s)

361-367

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Selective metabolism of vincristine in vitro by CYP3A5.

2 August 2017

cites work

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020258

Genetic variability in CYP3A5 and its possible consequences.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020258

Clinical and electrophysiological studies in vincristine induced neuropathy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020258

6 July 2018

Vincristine revisited

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020258

Clinical pharmacokinetics of vinorelbine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020258

Pharmacokinetics of vincristine in children and adolescents with acute lymphocytic leukemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020258

Vincristine disposition in children with acute lymphoblastic leukemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020258

Pharmacokinetics of vinorelbine in man.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020258

Clinical pharmacokinetics of vinorelbine alone and combined with cisplatin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020258

Vincristine pharmacokinetics after repetitive dosing in children.

6 July 2018

1 reference

Interpatient and intrapatient variability in vinblastine pharmacokinetics

21 January 2018

1 reference

Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

21 January 2018

1 reference

Pharmacokinetics of midazolam in CYP3A4- and CYP3A5-genotyped subjects

21 January 2018

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Quantification of vincristine and its major metabolite in human plasma by high-performance liquid chromatography/tandem mass spectrometry

21 January 2018

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Vincristine pharmacokinetics is related to clinical outcome in children with standard risk acute lymphoblastic leukemia

21 January 2018

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Grading of chemotherapy-induced peripheral neurotoxicity using the Total Neuropathy Scale

21 January 2018

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Multi-center assessment of the Total Neuropathy Score for chemotherapy-induced peripheral neurotoxicity.

21 January 2018

1 reference

Acute and long-term neurologic complications in children with acute lymphoblastic leukemia.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020258

Pharmacokinetics of vincristine sulfate in adult cancer patients

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020258

CYP3A4 is mainly responsibile for the metabolism of a new vinca alkaloid, vinorelbine, in human liver microsomes

27 October 2018

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12 December 2020

Effect of CYP3A5 expression on vincristine metabolism with human liver microsomes

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12 December 2020

Effect of race on vincristine-associated neurotoxicity in pediatric acute lymphoblastic leukemia patients

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12 December 2020

Vincristine in childhood leukaemia: no pharmacokinetic rationale for dose reduction in adolescents

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12 December 2020

The pharmacokinetics of vincristine in man: reduced drug clearance associated with raised serum alkaline phosphatase and dose-limited elimination

1 reference

12 December 2020

Clinical pharmacokinetics of the antitumor drug navelbine (5'-noranhydrovinblastine)

1 reference

12 December 2020

Uptake and metabolism of vinca alkaloids by freshly isolated human hepatocytes in suspension

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12 December 2020

The clinical pharmacokinetics of vinorelbine (Navelbine)

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12 December 2020

Appropriateness of maximum-dose guidelines for vincristine

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12 December 2020

Identifiers

DOI

10.1002/PBC.22845

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2 August 2017

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2 August 2017

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