(Q34487284)

2 August 2017

1 reference

title

Pharmacokinetics of methadone (English)

1 reference

2 August 2017

1 reference

Ralph A Lugo

1

1 reference

PubMed ID

16431829

2 August 2017

Kristin L Satterfield

series ordinal

2

1 reference

PubMed ID

16431829

2 August 2017

Steven E Kern

series ordinal

3

1 reference

2 August 2017

1 January 2005

1 reference

Journal of Pain and Palliative Care Pharmacotherapy

2 August 2017

1 reference

2 August 2017

19

1 reference

2 August 2017

4

1 reference

2 August 2017

13-24

1 reference

Opioid analgesics as noncompetitive N-methyl-D-aspartate (NMDA) antagonists

2 August 2017

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Interindividual variability of the clinical pharmacokinetics of methadone: implications for the treatment of opioid dependence

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Methadone--metabolism, pharmacokinetics and interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Bioavailabilities of rectal and oral methadone in healthy subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Rectal methadone in cancer patients with pain. A preliminary clinical and pharmacokinetic study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Ultrafiltration using the Amicon MPS-1 for assessing methadone plasma protein binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Methadone binding to orosomucoid (alpha 1-acid glycoprotein): determinant of free fraction in plasma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Methadone distribution and excretion into breast milk of clients in a methadone maintenance programme

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Distribution of R- and S-methadone into human milk during multiple, medium to high oral dosing

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Review article: perioperative pain management of patients on methadone therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Role of hepatic and intestinal cytochrome P450 3A and 2B6 in the metabolism, disposition, and miotic effects of methadone

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Methadone N-demethylation in human liver microsomes: lack of stereoselectivity and involvement of CYP3A4

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Fluvoxamine and fluoxetine do not interact in the same way with the metabolism of the enantiomers of methadone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Involvement of CYP3A4, CYP2C8, and CYP2D6 in the metabolism of (R)- and (S)-methadone in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Stereoselective metabolism of methadone N-demethylation by cytochrome P4502B6 and 2C19.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Pharmacokinetics and pharmacodynamics of methadone enantiomers after a single oral dose of racemate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Pharmacokinetics and pharmacodynamics of methadone in patients with chronic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Estimation of methadone clearance: application in the management of cancer pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Stereoselective pharmacokinetics of methadone in chronic pain patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Population pharmacokinetics of (R)-, (S)- and rac-methadone in methadone maintenance patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Population-based pharmacokinetic approach for methadone monitoring of opiate addicts: potential clinical utility

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Population pharmacokinetics of methadone in opiate users: characterization of time-dependent changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

The relationship of pharmacokinetics to pharmacological activity: morphine, methadone and naloxone

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Opioids in renal failure and dialysis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Rifampin-Induced Methadone Withdrawal

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

The pharmacokinetics of methadone in HIV-positive patients receiving the non-nucleoside reverse transcriptase inhibitor efavirenz

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Pharmacokinetics and pharmacodynamics of methadone enantiomers after coadministration with amprenavir in opioid-dependent subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Methadone blood concentrations are decreased by the administration of abacavir plus amprenavir

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Effect of tenofovir disoproxil fumarate on the pharmacokinetics and pharmacodynamics of total, R-, and S-methadone

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

The effects of methadone and its role in fatalities

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

The effect of fluconazole on the clinical pharmacokinetics of methadone

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

The effects of once-daily saquinavir/minidose ritonavir on the pharmacokinetics of methadone

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Effects of grapefruit juice on the pharmacokinetics of the enantiomers of methadone

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

A single dose of methadone inhibits cytochrome P-4503A activity in healthy volunteers as assessed by the urinary cortisol ratio

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

The effect of sertraline on methadone plasma levels in methadone-maintenance patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Pharmacokinetic-pharmacodynamic relationship of the selective serotonin reuptake inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Paroxetine increases steady-state concentrations of (R)-methadone in CYP2D6 extensive but not poor metabolizers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Brain penetration of methadone (R)- and (S)-enantiomers is greatly increased by P-glycoprotein deficiency in the blood-brain barrier of Abcb1a gene knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Effect of P-glycoprotein inhibition on methadone analgesia and brain distribution in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

The effect of quinidine, used as a probe for the involvement of P-glycoprotein, on the intestinal absorption and pharmacodynamics of methadone

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Role of P-glycoprotein in pharmacokinetics: clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Clinical pharmacology of opioids for pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Sublingual absorption of selected opioid analgesics

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Disposition of nasal, intravenous, and oral methadone in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Individual variability in the response to different opioids: report of five cases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Comparative pharmacodynamics and pharmacokinetics of methadone and slow-release oral morphine for maintenance treatment of opioid dependence

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Methadone in the management of cancer pain: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Alterations in methadone metabolism during late pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Can we use methadone for analgesia in neonates?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Enteral methadone to expedite fentanyl discontinuation and prevent opioid abstinence syndrome in the PICU.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Outpatient therapy of iatrogenic drug dependency following prolonged sedation in the pediatric intensive care unit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Fluoxetine Addition to Methadone in Addicts: Pharmacokinetic Aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Cytochrome P450 2D6 Genotype and Methadone Steady-State Concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

Efavirenz decreases methadone blood concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2FJ354V19N04_05

21 January 2018

Identifiers

DOI

10.1080/J354V19N04_05

1 reference

2 August 2017

1 reference

PubMed ID

16431829