(Q34487653)

2 August 2017

Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53 (English)

1 reference

V-set immunoregulatory receptor

2 August 2017

0 references

1 reference

identical protein binding

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Kyoung Wan Yoon

1

1 reference

2 August 2017

Sanguine Byun

2

1 reference

2 August 2017

Eunjeong Kwon

3

1 reference

2 August 2017

So-Young Hwang

4

1 reference

2 August 2017

Kiki Chu

5

1 reference

2 August 2017

Masatsugu Hiraki

6

1 reference

2 August 2017

Seung-Hee Jo

7

1 reference

2 August 2017

Astrid Weins

8

1 reference

2 August 2017

Samy Hakroush

9

1 reference

2 August 2017

Angelika Cebulla

10

1 reference

2 August 2017

David B Sykes

11

1 reference

2 August 2017

Anna Greka

12

1 reference

2 August 2017

Peter Mundel

13

1 reference

2 August 2017

David E Fisher

14

1 reference

2 August 2017

Anna Mandinova

15

1 reference

2 August 2017

Sam W Lee

16

1 reference

2 August 2017

language of work or name

English

0 references

publication date

1 July 2015

1 reference

2 August 2017

1 reference

2 August 2017

349

1 reference

2 August 2017

6247

1 reference

2 August 2017

1261669

1 reference

describes a project that uses

2 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5215039/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Role of p53 in systemic autoimmune diseases

1 reference

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Disruption of the immune-checkpoint VISTA gene imparts a proinflammatory phenotype with predisposition to the development of autoimmunity.

6 July 2018

1 reference

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Caught in the cross fire: p53 in inflammation.

6 July 2018

1 reference

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Caspase-mediated cleavage of phospholipid flippase for apoptotic phosphatidylserine exposure

6 July 2018

1 reference

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VISTA is a novel broad-spectrum negative checkpoint regulator for cancer immunotherapy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Downmodulation of tumor suppressor p53 by T cell receptor signaling is critical for antigen-specific CD4(+) T cell responses

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Coinhibitory receptor PD-1H preferentially suppresses CD4⁺ T cell-mediated immunity

6 July 2018

1 reference

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VISTA Regulates the Development of Protective Antitumor Immunity

6 July 2018

1 reference

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The receptors CD96 and CD226 oppose each other in the regulation of natural killer cell functions

6 July 2018

1 reference

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Apoptotic cell clearance: basic biology and therapeutic potential.

6 July 2018

1 reference

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EMAGE mouse embryo spatial gene expression database: 2014 update

6 July 2018

1 reference

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The scavenger receptor SCARF1 mediates the clearance of apoptotic cells and prevents autoimmunity

6 July 2018

1 reference

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6 July 2018

1 reference

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Non-cell-autonomous tumor suppression by p53.

6 July 2018

1 reference

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p53 controls autoimmune arthritis via STAT-mediated regulation of the Th17 cell/Treg cell balance in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Epidemiology and sociodemographics of systemic lupus erythematosus and lupus nephritis among US adults with Medicaid coverage, 2000-2004

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Inhibition of Stabilin-2 elevates circulating hyaluronic acid levels and prevents tumor metastasis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Does Δ133p53 isoform trigger inflammation and autoimmunity?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Continued clearance of apoptotic cells critically depends on the phagocyte Ucp2 protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Cutting edge: A monoclonal antibody specific for the programmed death-1 homolog prevents graft-versus-host disease in mouse models

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Trp53 negatively regulates autoimmunity via the STAT3-Th17 axis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

VISTA, a novel mouse Ig superfamily ligand that negatively regulates T cell responses

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

GI24 enhances tumor invasiveness by regulating cell surface membrane-type 1 matrix metalloproteinase.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Clearance of apoptotic cells: implications in health and disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

The role of defective clearance of apoptotic cells in systemic autoimmunity.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Phosphatidylserine receptor Tim-4 is essential for the maintenance of the homeostatic state of resident peritoneal macrophages

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

T and B cell hyperactivity and autoimmunity associated with niche-specific defects in apoptotic body clearance in TIM-4-deficient mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Autoimmunity and the clearance of dead cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

T Cell/Transmembrane, Ig, and Mucin-3 Allelic Variants Differentially Recognize Phosphatidylserine and Mediate Phagocytosis of Apoptotic Cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Foxp3 expression in p53-dependent DNA damage responses

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Differentiation of embryonic stem cells 1 (Dies1) is a component of bone morphogenetic protein 4 (BMP4) signaling pathway required for proper differentiation of mouse embryonic stem cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Effects of increased renal tubular vascular endothelial growth factor (VEGF) on fibrosis, cyst formation, and glomerular disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

6 July 2018

Modes of p53 regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Immunogenic and tolerogenic cell death

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

p53 regulates Toll-like receptor 3 expression and function in human epithelial cell lines

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Transcriptional role of p53 in interferon-mediated antiviral immunity.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

C1q binds phosphatidylserine and likely acts as a multiligand-bridging molecule in apoptotic cell recognition

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

PPARalpha agonist fenofibrate suppresses tumor growth through direct and indirect angiogenesis inhibition.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

TIM-1 and TIM-4 glycoproteins bind phosphatidylserine and mediate uptake of apoptotic cells.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Identification of Tim4 as a phosphatidylserine receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Living with p53, dying of p53.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

CDIP, a novel pro-apoptotic gene, regulates TNFalpha-mediated apoptosis in a p53-dependent manner

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Structures of T Cell immunoglobulin mucin receptors 1 and 2 reveal mechanisms for regulation of immune responses by the TIM receptor family

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Autophagy gene-dependent clearance of apoptotic cells during embryonic development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

RhoE is a pro-survival p53 target gene that inhibits ROCK I-mediated apoptosis in response to genotoxic stress

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Systemic lupus erythematosus: multiple immunological phenotypes in a complex genetic disease.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Persistence of apoptotic cells without autoimmune disease or inflammation in CD14-/- mice.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Phosphatidylserine receptor is required for the engulfment of dead apoptotic cells and for normal embryonic development in zebrafish

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Apoptosis and genomic instability

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Renal manifestations of systemic autoimmune disease: diagnosis and therapy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

A gene atlas of the mouse and human protein-encoding transcriptomes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Phosphatidylserine receptor is required for clearance of apoptotic cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Identification of a factor that links apoptotic cells to phagocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Role for p53 in gene induction by double-stranded RNA.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Phagocytosis and clearance of apoptotic cells is mediated by MER.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

p53 induction of heparin-binding EGF-like growth factor counteracts p53 growth suppression through activation of MAPK and PI3K/Akt signaling cascades

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

6 July 2018

Surfing the p53 network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Tumor suppressor p53 is required to modulate BRCA1 expression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

B cells from patients with systemic lupus erythematosus display abnormal antigen receptor-mediated early signal transduction events

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Wild-type p53 adopts a 'mutant'-like conformation when bound to DNA.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

WAF1, a potential mediator of p53 tumor suppression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Cancer. p53, guardian of the genome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Rapid cell corpse clearance by stabilin-2, a membrane phosphatidylserine receptor

6 July 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1261669

Identification of the interferon regulatory factor 5 gene (IRF-5) as a direct target for p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1261669

Loss of phospholipid asymmetry and surface exposure of phosphatidylserine is required for phagocytosis of apoptotic cells by macrophages and fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1261669

Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1261669

Repeat-induced gene silencing in mammals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1261669

TIM-4 is the ligand for TIM-1, and the TIM-1-TIM-4 interaction regulates T cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1261669

21 January 2018

Gone but not forgotten

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1261669

Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5215039

Regulatory role of p53 in experimental autoimmune encephalomyelitis

9 December 2018

1 reference

12 December 2020

Apoptosis and autoimmune diseases

1 reference

12 December 2020

p53 keeps bystanders at the gates

1 reference

12 December 2020

Tumor suppressor p53 inhibits systemic autoimmune diseases by inducing regulatory T cells

1 reference

12 December 2020

Phosphatidylserine exposure during apoptosis is a cell-type-specific event and does not correlate with plasma membrane phospholipid scramblase expression

1 reference

12 December 2020

Tumor suppressor p53 inhibits autoimmune inflammation and macrophage function.

1 reference

12 December 2020

Identifiers

DOI

10.1126/SCIENCE.1261669

1 reference

2 August 2017

1 reference

2 August 2017

1 reference