(Q34488569)

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Quantitative proteomic analysis identifies targets and pathways of a 2-aminobenzamide HDAC inhibitor in Friedreich's ataxia patient iPSC-derived neural stem cells.

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24933366%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Quantitative proteomic analysis identifies targets and pathways of a 2-aminobenzamide HDAC inhibitor in Friedreich's ataxia patient iPSC-derived neural stem cells (English)

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Europe PubMed Central

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20 March 2020

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Friedreich ataxia

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neural stem cell

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3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24933366%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Joel M. Gottesfeld

5

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20 March 2020

author name string

Bing Shan

1

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20 March 2020

Chunping Xu

2

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20 March 2020

Tao Xu

4

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20 March 2020

John R Yates

6

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20 March 2020

publication date

26 June 2014

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24933366%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Journal of Proteome Research

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20 March 2020

13

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20 March 2020

11

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20 March 2020

4558-4566

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24933366%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Core small nuclear ribonucleoprotein particle splicing factor SmD1 modulates RNA interference in Drosophila

1 reference

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6 July 2018

Increasing frataxin gene expression with histone deacetylase inhibitors as a therapeutic approach for Friedreich's ataxia.

1 reference

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6 July 2018

Gene regulation and epigenetics in Friedreich's ataxia

1 reference

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1 reference

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1 reference

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6 July 2018

A SWI/SNF chromatin-remodeling complex acts in noncoding RNA-mediated transcriptional silencing

1 reference

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6 July 2018

Chromatin acetylation at transcription start sites and vitamin D receptor binding regions relates to effects of 1α,25-dihydroxyvitamin D3 and histone deacetylase inhibitors on gene expression

1 reference

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6 July 2018

Selective histone deacetylase (HDAC) inhibition imparts beneficial effects in Huntington's disease mice: implications for the ubiquitin-proteasomal and autophagy systems.

1 reference

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6 July 2018

Role of mismatch repair enzymes in GAA·TTC triplet-repeat expansion in Friedreich ataxia induced pluripotent stem cells

1 reference

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6 July 2018

Histone deacetylase (HDAC) inhibitors targeting HDAC3 and HDAC1 ameliorate polyglutamine-elicited phenotypes in model systems of Huntington's disease.

1 reference

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6 July 2018

A gene expression phenotype in lymphocytes from Friedreich ataxia patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227551

6 July 2018

Prolonged treatment with pimelic o-aminobenzamide HDAC inhibitors ameliorates the disease phenotype of a Friedreich ataxia mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227551

6 July 2018

Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227551

6 July 2018

Two new pimelic diphenylamide HDAC inhibitors induce sustained frataxin upregulation in cells from Friedreich's ataxia patients and in a mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227551

6 July 2018

Chemical probes identify a role for histone deacetylase 3 in Friedreich's ataxia gene silencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227551

6 July 2018

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227551

6 July 2018

Pimelic diphenylamide 106 is a slow, tight-binding inhibitor of class I histone deacetylases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227551

6 July 2018

The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227551

6 July 2018

Therapeutic application of histone deacetylase inhibitors for central nervous system disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227551

6 July 2018

Acetylation of non-histone proteins modulates cellular signalling at multiple levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227551

6 July 2018

HDAC inhibitors correct frataxin deficiency in a Friedreich ataxia mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227551

6 July 2018

A quantitative analysis software tool for mass spectrometry-based proteomics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227551

6 July 2018

Chemical origins of isoform selectivity in histone deacetylase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227551

6 July 2018

Activity-based probes for proteomic profiling of histone deacetylase complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227551

6 July 2018

Histone deacetylase inhibitors reverse gene silencing in Friedreich's ataxia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227551

6 July 2018

Lost in translation: the influence of ribosomes on bacterial mRNA decay

1 reference

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6 July 2018

The large spectrum of eIF2B-related diseases

1 reference

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6 July 2018

DTASelect and Contrast: tools for assembling and comparing protein identifications from shotgun proteomics

1 reference

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6 July 2018

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1 reference

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A novel shuttling protein, 4E-T, mediates the nuclear import of the mRNA 5' cap-binding protein, eIF4E

1 reference

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6 July 2018

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mRNA stability in mammalian cells

1 reference

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227551

6 July 2018

A fraction of the mRNA 5' cap-binding protein, eukaryotic initiation factor 4E, localizes to the nucleus

1 reference

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Molecular and functional alterations in a mouse cardiac model of Friedreich ataxia: activation of the integrated stress response, eIF2α phosphorylation, and the induction of downstream targets.

1 reference

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1 reference

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1 reference

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA triplet repeats mediate heterochromatin-protein-1-sensitive variegated gene silencing

1 reference

https://pubmed.ncbi.nlm.nih.gov/24933366

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Friedreich ataxia

1 reference

https://pubmed.ncbi.nlm.nih.gov/24933366

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/PR500514R

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24933366%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

PMC publication ID

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Europe PubMed Central

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20 March 2020

PubMed publication ID

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Europe PubMed Central

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20 March 2020

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