(Q34490664)

2 August 2017

title

Rhodopsin gene expression determines rod outer segment size and rod cell resistance to a dominant-negative neurodegeneration mutant (English)

1 reference

2 August 2017

1 reference

Theodore G Wensel

6

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author name string

Brandee A Price

1

1 reference

2 August 2017

Ivette M Sandoval

2

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2 August 2017

Fung Chan

3

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2 August 2017

Ralph Nichols

4

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2 August 2017

Ramon Roman-Sanchez

5

1 reference

2 August 2017

John H Wilson

7

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2 August 2017

language of work or name

English

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publication date

21 November 2012

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2 August 2017

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2 August 2017

volume

7

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2 August 2017

issue

11

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2 August 2017

page(s)

e49889

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Creative Commons Attribution 4.0 International

2 August 2017

copyright license

start time

21 November 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3503812/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Rhodopsin expression level affects rod outer segment morphology and photoresponse kinetics

1 reference

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Rhodopsin mutant P23H destabilizes rod photoreceptor disk membranes

6 July 2018

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Mislocalization and degradation of human P23H-rhodopsin-GFP in a knockin mouse model of retinitis pigmentosa

6 July 2018

1 reference

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Efficient mutagenesis of the rhodopsin gene in rod photoreceptor neurons in mice

6 July 2018

1 reference

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Suppression and replacement gene therapy for autosomal dominant disease in a murine model of dominant retinitis pigmentosa

6 July 2018

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Probing mechanisms of photoreceptor degeneration in a new mouse model of the common form of autosomal dominant retinitis pigmentosa due to P23H opsin mutations

6 July 2018

1 reference

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AAV delivery of wild-type rhodopsin preserves retinal function in a mouse model of autosomal dominant retinitis pigmentosa

6 July 2018

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Restoration of visual function in P23H rhodopsin transgenic rats by gene delivery of BiP/Grp78

6 July 2018

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Overexpression of rhodopsin alters the structure and photoresponse of rod photoreceptors.

6 July 2018

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Pharmacological manipulation of gain-of-function and dominant-negative mechanisms in rhodopsin retinitis pigmentosa.

6 July 2018

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Impaired photoreceptor protein transport and synaptic transmission in a mouse model of Bardet-Biedl syndrome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503812

IRE1 signaling affects cell fate during the unfolded protein response

6 July 2018

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6 July 2018

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Trafficking of G protein-coupled receptors

6 July 2018

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Mechanisms of cell death in rhodopsin retinitis pigmentosa: implications for therapy

6 July 2018

1 reference

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Suppression of wild-type rhodopsin maturation by mutants linked to autosomal dominant retinitis pigmentosa

6 July 2018

1 reference

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Rhodopsin signaling and organization in heterozygote rhodopsin knockout mice

6 July 2018

1 reference

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Knock-in human rhodopsin-GFP fusions as mouse models for human disease and targets for gene therapy

6 July 2018

1 reference

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The nature of dominant mutations of rhodopsin and implications for gene therapy

6 July 2018

1 reference

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The cellular fate of mutant rhodopsin: quality control, degradation and aggresome formation.

6 July 2018

1 reference

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On the genetics of retinitis pigmentosa and on mutation-independent approaches to therapeutic intervention

6 July 2018

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Mutant rhodopsin transgene expression on a null background

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503812

The relationship between opsin overexpression and photoreceptor degeneration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503812

Novel rhodopsin mutations Gly114Val and Gln184Pro in dominant retinitis pigmentosa.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503812

EMAN: semiautomated software for high-resolution single-particle reconstructions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503812

Morphological, physiological, and biochemical changes in rhodopsin knockout mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503812

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503812

Defective phototransductive disk membrane morphogenesis in transgenic mice expressing opsin with a mutated N-terminal domain.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503812

Transgenic mice carrying the dominant rhodopsin mutation P347S: evidence for defective vectorial transport of rhodopsin to the outer segments

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503812

Dominant-negative p53 mutations selected in yeast hit cancer hot spots

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503812

Simulation of human autosomal dominant retinitis pigmentosa in transgenic mice expressing a mutated murine opsin gene

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503812

Constitutive activation of phototransduction by K296E opsin is not a cause of photoreceptor degeneration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503812

Preparation and properties of phospholipid bilayers containing rhodopsin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503812

A point mutation of the rhodopsin gene in one form of retinitis pigmentosa

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503812

Transgenic mice with a rhodopsin mutation (Pro23His): a mouse model of autosomal dominant retinitis pigmentosa

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503812

A rhodopsin mutant linked to autosomal dominant retinitis pigmentosa is prone to aggregate and interacts with the ubiquitin proteasome system

6 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0049889

The carboxyl-terminal domain is essential for rhodopsin transport in rod photoreceptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0049889

Structural and functional rescue of murine rod photoreceptors by human rhodopsin transgene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0049889

Developmental death of photoreceptors in the C57BL/6J mouse: association with retinal function and self-protection

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0049889

Ribozyme rescue of photoreceptor cells in a transgenic rat model of autosomal dominant retinitis pigmentosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0049889

Knockdown of wild-type mouse rhodopsin using an AAV vectored ribozyme as part of an RNA replacement approach

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503812

Hammerhead ribozymes designed to cleave all human rod opsin mRNAs which cause autosomal dominant retinitis pigmentosa.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503812

Cell death in normal development

27 October 2018

1 reference

12 December 2020

Rhodopsin accumulation at abnormal sites in retinas of mice with a human P23H rhodopsin transgene

1 reference

12 December 2020

Functional abnormalities in transgenic mice expressing a mutant rhodopsin gene

1 reference

12 December 2020

Retinopathy induced in mice by targeted disruption of the rhodopsin gene

1 reference

12 December 2020

Strategems in vitro for gene therapies directed to dominant mutations

1 reference

12 December 2020

Opsin localization and rhodopsin photochemistry in a transgenic mouse model of retinitis pigmentosa

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0049889

Identifiers

DOI

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2 August 2017

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2 August 2017

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