(Q34495636)

2 August 2017

CYP2B6 c.983T>C polymorphism is associated with nevirapine hypersensitivity in Malawian and Ugandan HIV populations (English)

1 reference

2 August 2017

0 references

1 reference

David G Lalloo

11

0 references

Munir Pirmohamed

Munir Pirmohamed

13

0 references

Robert Heyderman

Robert S Heyderman

12

0 references

Daniel Carr

Daniel F Carr

1

0 references

Collet Dandara

7

Collet Dandara

1 reference

2 August 2017

9

Francis Ssali

1 reference

2 August 2017

Joep J van Oosterhout

6

Joep J Van Oosterhout

1 reference

2 August 2017

Mas Chaponda

2

1 reference

2 August 2017

Elena M Cornejo Castro

3

1 reference

2 August 2017

Andrea L Jorgensen

4

1 reference

2 August 2017

Saye Khoo

5

1 reference

2 August 2017

Elizabeth Kampira

8

1 reference

2 August 2017

Paula Munderi

10

1 reference

2 August 2017

language of work or name

English

0 references

publication date

20 August 2014

1 reference

2 August 2017

6

1 reference

Journal of Antimicrobial Chemotherapy

inferred from page(s)

published in

1 reference

2 August 2017

69

1 reference

2 August 2017

3329-3334

1 reference

2 August 2017

12

1 reference

Population pharmacokinetic and pharmacogenetic analysis of nevirapine in hypersensitive and tolerant HIV-infected patients from Malawi

2 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228781

Clinical and genetic determinants of plasma nevirapine exposure following an intrapartum dose to prevent mother-to-child HIV transmission

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228781

Association of human leukocyte antigen alleles and nevirapine hypersensitivity in a Malawian HIV-infected population

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228781

Underlying genetic structure impacts the association between CYP2B6 polymorphisms and response to efavirenz and nevirapine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228781

Nevirapine pharmacokinetics and risk of rash and hepatitis among HIV-infected sub-Saharan African women

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228781

Toxicogenomics of nevirapine-associated cutaneous and hepatic adverse events among populations of African, Asian, and European descent

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228781

Distribution of HLA-B alleles in a Ugandan HIV-infected adult population: NORA pharmacogenetic substudy of DART.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228781

Routine versus clinically driven laboratory monitoring of HIV antiretroviral therapy in Africa (DART): a randomised non-inferiority trial

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228781

Risk factors for treatment-limiting toxicities in patients starting nevirapine-containing antiretroviral therapy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228781

Impact of CYP2B6 983T>C polymorphism on non-nucleoside reverse transcriptase inhibitor plasma concentrations in HIV-infected patients

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228781

Discontinuation of nevirapine because of hypersensitivity reactions in patients with prior treatment experience, compared with treatment-naive patients: the ATHENA cohort study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228781

Cytochrome P450 2B6 (CYP2B6) G516T influences nevirapine plasma concentrations in HIV-infected patients in Uganda

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228781

Toxic epidermal necrolysis and Stevens Johnson syndrome: our current understanding

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228781

Predisposition to nevirapine hypersensitivity associated with HLA-DRB1*0101 and abrogated by low CD4 T-cell counts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228781

Medical genetics: a marker for Stevens-Johnson syndrome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228781

Predisposition to abacavir hypersensitivity conferred by HLA-B*5701 and a haplotypic Hsp70-Hom variant

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228781

Nevirapine and the risk of Stevens-Johnson syndrome or toxic epidermal necrolysis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228781

Quantification and cellular localization of expression in human skin of genes encoding flavin-containing monooxygenases and cytochromes P450

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228781

Sex differences in nevirapine rash

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228781

Further characterization of the expression in liver and catalytic activity of CYP2B6.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228781

Hepatotoxicity following nevirapine-containing regimens in HIV-1-infected individuals

6 July 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKU315

HLA-DRB1*01 associated with cutaneous hypersensitivity induced by nevirapine and efavirenz

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKU315

HLA-B*3505 allele is a strong predictor for nevirapine-induced skin adverse drug reactions in HIV-infected Thai patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKU315

Functional characterization of cytochrome P450 2B6 allelic variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKU315

Influence of CYP2B6 polymorphism on plasma and intracellular concentrations and toxicity of efavirenz and nevirapine in HIV-infected patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKU315

Nevirapine-induced hepatotoxicity and pharmacogenetics: a retrospective study in a population from Mozambique

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKU315

Evaluation of naranjo adverse drug reactions probability scale in causality assessment of drug-induced liver injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKU315

Association between CYP2B6 polymorphisms and Nevirapine-induced SJS/TEN: a pharmacogenetics study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKU315

Genetic variability of CYP2B6 in populations of African and Asian origin: allele frequencies, novel functional variants, and possible implications for anti-HIV therapy with efavirenz

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKU315

Cytochrome P450 2B6 516G-->T is associated with plasma concentrations of nevirapine at both 200 mg twice daily and 400 mg once daily in an ethnically diverse population

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKU315

Association of high T allele frequency of CYP2B6 G516T polymorphism among ethnic south Indian HIV-infected patients with elevated plasma efavirenz and nevirapine

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKU315

Incidence and risk factors for nevirapine-associated rash

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKU315

Functional characterization of 26 CYP2B6 allelic variants (CYP2B6.2-CYP2B6.28, except CYP2B6.22).

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228781

Disposition and biotransformation of the antiretroviral drug nevirapine in humans.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228781

Determinants of nevirapine hypersensitivity and its effect on the association between hepatitis C status and mortality in antiretroviral drug-naive HIV-positive patients

27 October 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKU315

Human cytochrome P4502B6: interindividual hepatic expression, substrate specificity, and role in procarcinogen activation

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4228781

Pharmacogenetics of nevirapine-associated hepatotoxicity: an Adult AIDS Clinical Trials Group collaboration

9 December 2018

1 reference

12 December 2020

HLA-Cw8 primarily associated with hypersensitivity to nevirapine

1 reference

12 December 2020

Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver

1 reference

12 December 2020

Clinical detection and assessment of drug induced neurotoxicity

1 reference

12 December 2020

A fast method for high-quality genomic DNA extraction from whole human blood

1 reference

12 December 2020

Identifiers

DOI

10.1093/JAC/DKU315

1 reference

2 August 2017

1 reference

2 August 2017

1 reference