(Q34501717)

2 August 2017

title

Apical and basolateral pools of proteinase-activated receptor-2 direct distinct signaling events in the intestinal epithelium (English)

1 reference

2 August 2017

Christian Lytle

2

0 references

author name string

Chang Lau

series ordinal

1

1 reference

2 August 2017

Daniel S Straus

series ordinal

3

1 reference

2 August 2017

Kathryn A DeFea

series ordinal

4

1 reference

2 August 2017

publication date

10 November 2010

1 reference

American Journal of Physiology - Cell Physiology

2 August 2017

published in

1 reference

2 August 2017

volume

300

1 reference

2 August 2017

issue

1

1 reference

2 August 2017

page(s)

C113-23

1 reference

beta-Arrestins scaffold cofilin with chronophin to direct localized actin filament severing and membrane protrusions downstream of protease-activated receptor-2.

2 August 2017

cites work

1 reference

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7 July 2018

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Protease-activated receptor-2 stimulates intestinal epithelial chloride transport through activation of PLC and selective PKC isoforms

7 July 2018

1 reference

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Prostaglandin E2 derived from cyclooxygenases 1 and 2 mediates intestinal epithelial ion transport stimulated by the activation of protease-activated receptor 2.

7 July 2018

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{beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation

7 July 2018

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Neutrophil-mediated activation of epithelial protease-activated receptors-1 and -2 regulates barrier function and transepithelial migration

7 July 2018

1 reference

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Kallikreins and proteinase-mediated signaling: proteinase-activated receptors (PARs) and the pathophysiology of inflammatory diseases and cancer

7 July 2018

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Derivatized 2-furoyl-LIGRLO-amide, a versatile and selective probe for proteinase-activated receptor 2: binding and visualization

7 July 2018

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Helicobacter pylori activates gastric epithelial cells to produce interleukin-8 via protease-activated receptor 2.

7 July 2018

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EGF receptor transactivation and MAP kinase mediate proteinase-activated receptor-2-induced chloride secretion in intestinal epithelial cells

7 July 2018

1 reference

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Fenofibrate inhibits intestinal Cl- secretion by blocking basolateral KCNQ1 K+ channels

7 July 2018

1 reference

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Protease-activated receptor 2, dipeptidyl peptidase I, and proteases mediate Clostridium difficile toxin A enteritis.

7 July 2018

1 reference

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Beta-arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2

7 July 2018

1 reference

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Differential effects of beta-arrestins on the internalization, desensitization and ERK1/2 activation downstream of protease activated receptor-2.

7 July 2018

1 reference

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Stop that cell! Beta-arrestin-dependent chemotaxis: a tale of localized actin assembly and receptor desensitization

7 July 2018

1 reference

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Protease-activated receptor-2 simultaneously directs beta-arrestin-1-dependent inhibition and Galphaq-dependent activation of phosphatidylinositol 3-kinase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023197

PAR-2 activation in intestinal epithelial cells potentiates interleukin-1beta-induced chemokine secretion via MAP kinase signaling pathways.

7 July 2018

1 reference

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Mast cell tryptase controls paracellular permeability of the intestine. Role of protease-activated receptor 2 and beta-arrestins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023197

Ion transport regulated by protease-activated receptor 2 in human airway Calu-3 epithelia

7 July 2018

1 reference

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A major role for proteolytic activity and proteinase-activated receptor-2 in the pathogenesis of infectious colitis

7 July 2018

1 reference

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Constitutive protease-activated receptor-2-mediated migration of MDA MB-231 breast cancer cells requires both beta-arrestin-1 and -2.

7 July 2018

1 reference

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Multiple independent functions of arrestins in the regulation of protease-activated receptor-2 signaling and trafficking

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023197

Proteinase-activated receptor-2: physiological and pathophysiological roles

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023197

Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023197

A beta-arrestin-dependent scaffold is associated with prolonged MAPK activation in pseudopodia during protease-activated receptor-2-induced chemotaxis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023197

Protease-activated receptors: the role of cell-surface proteolysis in signalling

7 July 2018

1 reference

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Induction of intestinal inflammation in mouse by activation of proteinase-activated receptor-2

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023197

Proteinase-activated receptor 2 is an anti-inflammatory signal for colonic lamina propria lymphocytes in a mouse model of colitis

7 July 2018

1 reference

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AP-1 in cell proliferation and survival

7 July 2018

1 reference

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Proteinase-activated receptors.

7 July 2018

1 reference

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Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates

7 July 2018

1 reference

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Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa

7 July 2018

1 reference

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beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2

7 July 2018

1 reference

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Functional activity of hepatocyte nuclear factor-1 is specifically decreased in amino acid-limited hepatoma cells

7 July 2018

1 reference

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Trafficking of proteinase-activated receptor-2 and beta-arrestin-1 tagged with green fluorescent protein. beta-Arrestin-dependent endocytosis of a proteinase receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023197

Thrombin and mast cell tryptase regulate guinea-pig myenteric neurons through proteinase-activated receptors-1 and -2.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023197

Mast cell tryptase regulates rat colonic myocytes through proteinase-activated receptor 2.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023197

Luminal trypsin may regulate enterocytes through proteinase-activated receptor 2.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023197

Detection of functional receptors for the proteinase-activated-receptor-2-activating polypeptide, SLIGRL-NH2, in rat vascular and gastric smooth muscle

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023197

Phosphorylation of the c-Fos transrepression domain by mitogen-activated protein kinase and 90-kDa ribosomal S6 kinase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023197

Positive and negative regulation of chloride secretion in T84 cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023197

Cytoplasmic to nuclear signal transduction by mitogen-activated protein kinase and 90 kDa ribosomal S6 kinase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023197

Regulation of pp90rsk phosphorylation and S6 phosphotransferase activity in Swiss 3T3 cells by growth factor-, phorbol ester-, and cyclic AMP-mediated signal transduction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023197

PAR2 activation alters colonic paracellular permeability in mice via IFN-gamma-dependent and -independent pathways

7 July 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00162.2010

Proteinase-activated receptor-2-induced colonic inflammation in mice: possible involvement of afferent neurons, nitric oxide, and paracellular permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00162.2010

Trypsin IV, a novel agonist of protease-activated receptors 2 and 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00162.2010

Basolateral PAR-2 receptors mediate KCl secretion and inhibition of Na+ absorption in the mouse distal colon

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00162.2010

ERK1/2 regulates ANG II-dependent cell proliferation via cytoplasmic activation of RSK2 and nuclear activation of elk1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00162.2010

Protease-activated receptor-2 activation: a major actor in intestinal inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00162.2010

Carbachol stimulates transactivation of epidermal growth factor receptor and mitogen-activated protein kinase in T84 cells. Implications for carbachol-stimulated chloride secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00162.2010

Differential regulation of chemokines by IL-17 in colonic epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00162.2010

Activation of ion secretion via proteinase-activated receptor-2 in human colon

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00162.2010

2-furoyl-LIGRLO-amide: a potent and selective proteinase-activated receptor 2 agonist.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00162.2010

The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00162.2010

Treatment of mildly to moderately active ulcerative colitis with a tryptase inhibitor (APC 2059): an open-label pilot study

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00162.2010

Differential regulation of class IA phosphoinositide 3-kinase catalytic subunits p110 alpha and beta by protease-activated receptor 2 and beta-arrestins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00162.2010

The proteinase-activated receptor 2 is involved in nociception.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023197

[PAR (protease-activated receptor) as a novel target for development of gastric mucosal cytoprotective drugs]

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21068362

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1152/AJPCELL.00162.2010

1 reference

release_ag4xfnxv4ngndjhcf3o7k473fq

2 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ag4xfnxv4ngndjhcf3o7k473fq

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

3023197

1 reference

2 August 2017

1 reference