(Q34503473)

English

Calories from carbohydrates: energetic contribution of the carbohydrate moiety of rebeccamycin to DNA binding and the effect of its orientation on topoisomerase I inhibition.

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7 December 2019

Calories from carbohydrates: energetic contribution of the carbohydrate moiety of rebeccamycin to DNA binding and the effect of its orientation on topoisomerase I inhibition (English)

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7 December 2019

Jonathan B. Chaires

5

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7 December 2019

author name string

Bailly C

1

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7 December 2019

Qu X

2

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7 December 2019

Graves DE

3

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7 December 2019

Prudhomme M

4

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7 December 2019

publication date

1 May 1999

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7 December 2019

Chemistry and Biology

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7 December 2019

6

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7 December 2019

5

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7 December 2019

277-286

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7 December 2019

Staurosporine, K-252 and UCN-01: potent but nonspecific inhibitors of protein kinases

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Isolation and structure of rebeccamycin - a new antitumor antibiotic from nocardia aerocoligenes

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Production and biological activity of rebeccamycin, a novel antitumor agent.

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AT2433-A1, AT2433-A2, AT2433-B1, and AT2433-B2 novel antitumor antibiotic compounds produced by Actinomadura melliaura. Taxonomy, fermentation, isolation and biological properties.

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Induction of mammalian DNA topoisomerase I mediated DNA cleavage by antitumor indolocarbazole derivatives

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Structure-activity relationships in a series of substituted indolocarbazoles: topoisomerase I and protein kinase C inhibition and antitumoral and antimicrobial properties

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DNA cleavage by topoisomerase I in the presence of indolocarbazole derivatives of rebeccamycin

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New chemotherapeutic agents for the treatment of non-small cell lung cancer: the Japanese experience

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Recognition of specific sequences in DNA by a topoisomerase I inhibitor derived from the antitumor drug rebeccamycin

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Thermodynamic analysis of ion effects on the binding and conformational equilibria of proteins and nucleic acids: the roles of ion association or release, screening, and ion effects on water activity

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Polyelectrolyte effects on site-binding equilibria with application to the intercalation of drugs into DNA.

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16 Analysis of equilibrium and kinetic measurements to determine thermodynamic origins of stability and specificity and mechanism of formation of site-specific complexes between proteins and helical DNA

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A fluorescent complex between ethidium bromide and nucleic acids. Physical-chemical characterization

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Criteria for the mode of binding of DNA binding agents.

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Syntheses and biological evaluation of indolocarbazoles, analogues of rebeccamycin, modified at the imide heterocycle

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Parsing the free energy of anthracycline antibiotic binding to DNA

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Strategies for the design of minor groove binders: a re-evaluation based on the emergence of site-selective carbohydrate binders

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Solution structure of the calicheamicin gamma 1I-DNA complex

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Solution structure of the esperamicin A1-DNA complex

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Saccharide-RNA recognition in an aminoglycoside antibiotic-RNA aptamer complex

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7 January 2021

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Interactions between an anthracycline antibiotic and DNA: molecular structure of daunomycin complexed to d(CpGpTpApCpG) at 1.2-A resolution

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Structural comparison of anticancer drug-DNA complexes: adriamycin and daunomycin

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7 January 2021

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Biophysical chemistry of the daunomycin-DNA interaction.

1 reference

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7 January 2021

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Syntheses and biological activities (topoisomerase inhibition and antitumor and antimicrobial properties) of rebeccamycin analogues bearing modified sugar moieties and substituted on the imide nitrogen with a methyl group.

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7 January 2021

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Identifiers

10.1016/S1074-5521(99)80073-8

1 reference

Europe PubMed Central

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7 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10322124%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

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