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HIV-1 gp120-mediated increases in IL-8 production in astrocytes are mediated through the NF-κB pathway and can be silenced by gp120-specific siRNA.
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Europe PubMed Central
PMC publication ID
3023744
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21190575%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
title
HIV-1 gp120-mediated increases in IL-8 production in astrocytes are mediated through the NF-κB pathway and can be silenced by gp120-specific siRNA
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3023744
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21190575%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
main subject
NF-κB
0 references
astrocyte
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author
Ankit Shah
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3023744
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21190575%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
author name string
Anil Kumar
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3023744
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21190575%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
publication date
29 December 2010
1 reference
stated in
Europe PubMed Central
PMC publication ID
3023744
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21190575%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
published in
Journal of Neuroinflammation
1 reference
stated in
Europe PubMed Central
PMC publication ID
3023744
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21190575%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
volume
7
1 reference
stated in
Europe PubMed Central
PMC publication ID
3023744
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21190575%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
page(s)
96
1 reference
stated in
Europe PubMed Central
PMC publication ID
3023744
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21190575%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
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HIV-1 viral envelope glycoprotein gp120 triggers an inflammatory response in cultured rat astrocytes and regulates the functional expression of P-glycoprotein
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Estrogen attenuates gp120- and tat1-72-induced oxidative stress and prevents loss of dopamine transporter function
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HIV-1 gp120-induced TNF-{alpha} production by primary human macrophages is mediated by phosphatidylinositol-3 (PI-3) kinase and mitogen-activated protein (MAP) kinase pathways.
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Inhibition of NF-kappaB activity by BAY 11-7082 increases apoptosis in multidrug resistant leukemic T-cell lines
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Human CNS cultures exposed to HIV-1 gp120 reproduce dendritic injuries of HIV-1-associated dementia
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Astrocyte infection by HIV-1: mechanisms of restricted virus replication, and role in the pathogenesis of HIV-1-associated dementia
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The HIV Env-mediated fusion reaction
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7 July 2018
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Dopaminergic neurotoxicity of HIV-1 gp120: reactive oxygen species as signaling intermediates
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HIV-1 viral envelope glycoprotein gp120 produces oxidative stress and regulates the functional expression of multidrug resistance protein-1 (Mrp1) in glial cells
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27 October 2018
A selective IKK-2 inhibitor blocks NF-kappa B-dependent gene expression in interleukin-1 beta-stimulated synovial fibroblasts
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The HIV envelope protein gp120 is toxic to human brain-cell cultures through the induction of interleukin-6 and tumor necrosis factor-alpha.
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Interleukin-1β Released by gp120 Drives Neural Death through Tyrosine Phosphorylation and Trafficking of NMDA Receptors
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Interleukin-8, neuroinflammation, and secondary brain injury
1 reference
stated in
PubMed
reference URL
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retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1186/1742-2094-7-96
1 reference
stated in
Europe PubMed Central
PMC publication ID
3023744
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21190575%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
Dimensions Publication ID
1031268138
0 references
Fatcat ID
release_eflubgfwn5bkrodrjwa35sp7tu
1 reference
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Fatcat
reference URL
https://api.fatcat.wiki/v0/release/eflubgfwn5bkrodrjwa35sp7tu
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PMC publication ID
3023744
1 reference
stated in
Europe PubMed Central
PMC publication ID
3023744
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21190575%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
PubMed publication ID
21190575
1 reference
stated in
Europe PubMed Central
PMC publication ID
3023744
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21190575%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
ResearchGate publication ID
49713914
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