(Q37711402)

English

Human airway smooth muscle cells from asthmatic individuals have CXCL8 hypersecretion due to increased NF-kappa B p65, C/EBP beta, and RNA polymerase II binding to the CXCL8 promoter

scientific article published on 04 September 2009

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Human airway smooth muscle cells from asthmatic individuals have CXCL8 hypersecretion due to increased NF-kappa B p65, C/EBP beta, and RNA polymerase II binding to the CXCL8 promoter (English)

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

0 references

1 reference

based on heuristic

inferred from title

object named as

Alan J Knox

5

0 references

author name string

Alison E John

1

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Yong M Zhu

2

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Christopher E Brightling

3

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Linhua Pang

4

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

language of work or name

0 references

publication date

4 September 2009

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Journal of Immunology

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

183

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

7

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

4682-4692

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Integrating cell-signalling pathways with NF-kappaB and IKK function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

23 August 2017

Good cop, bad cop: the different faces of NF-kappaB

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

23 August 2017

Airway smooth muscle: a modulator of airway remodeling in asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

23 August 2017

Phosphorylation of serine 468 by GSK-3beta negatively regulates basal p65 NF-kappaB activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

23 August 2017

Synthetic responses in airway smooth muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

23 August 2017

The role of interleukin-8 and its receptors in inflammatory lung disease: implications for therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

23 August 2017

Transcriptional regulation of cyclooxygenase 2 by bradykinin and interleukin-1beta in human airway smooth muscle cells: involvement of different promoter elements, transcription factors, and histone h4 acetylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

23 August 2017

Chemokines and asthma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

23 August 2017

Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

23 August 2017

Multiple control of interleukin-8 gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

23 August 2017

Changes in biophysical and biochemical properties of single bronchial smooth muscle cells from asthmatic subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

23 August 2017

Nf-kappa B, chemokine gene transcription and tumour growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

23 August 2017

Signal transduction by the JNK group of MAP kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

23 August 2017

IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

23 August 2017

Stimulus-specific regulation of chemokine expression involves differential activation of the redox-responsive transcription factors AP-1 and NF-kappaB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

23 August 2017

Cross-talk between transcription factors NF-kappa B and C/EBP in the transcriptional regulation of genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

23 August 2017

The transcriptional activity of NF-kappaB is regulated by the IkappaB-associated PKAc subunit through a cyclic AMP-independent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

23 August 2017

Distinct mechanisms for regulation of the interleukin-8 gene involve synergism and cooperativity between C/EBP and NF-kappa B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

23 August 2017

Functional and physical associations between NF-kappa B and C/EBP family members: a Rel domain-bZIP interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

23 August 2017

Phosphorylation of c-jun mediated by MAP kinases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

23 August 2017

H2O2 and tumor necrosis factor-alpha induce differential binding of the redox-responsive transcription factors AP-1 and NF-kappaB to the interleukin-8 promoter in endothelial and epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

6 September 2017

Inflammatory cytokine production by human neutrophils involves C/EBP transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

14 September 2017

Chemokine concentrations and mast cell chemotactic activity in BAL fluid in patients with eosinophilic bronchitis and asthma, and in normal control subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

14 September 2017

Mast cell migration to Th2 stimulated airway smooth muscle from asthmatics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

14 September 2017

IKKbeta phosphorylates p65 at S468 in transactivaton domain 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

14 September 2017

beta2-Adrenoceptor agonists, like glucocorticoids, repress eotaxin gene transcription by selective inhibition of histone H4 acetylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

14 September 2017

Differential expression of CCR3 and CXCR3 by human lung and bone marrow-derived mast cells: implications for tissue mast cell migration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

14 September 2017

Transcriptional regulation of interleukin (IL)-8 by bradykinin in human airway smooth muscle cells involves prostanoid-dependent activation of AP-1 and nuclear factor (NF)-IL-6 and prostanoid-independent activation of NF-kappaB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

14 September 2017

A promoter recruitment mechanism for tumor necrosis factor-alpha-induced interleukin-8 transcription in type II pulmonary epithelial cells. Dependence on nuclear abundance of Rel A, NF-kappaB1, and c-Rel transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

28 September 2017

Synthetic functions of airway smooth muscle in asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

28 September 2017

Tumor necrosis factor-induced interleukin-8 expression in cultured human airway epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

28 September 2017

Airway smooth muscle cell proliferation is increased in asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

23 June 2018

Increased neutrophil numbers and IL-8 levels in airway secretions in acute severe asthma: Clinical and biologic significance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

23 June 2018

Interleukin 8 and monocyte chemoattractant protein 1 production by cultured human airway smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

23 June 2018

Inhibition of tumor necrosis factor-alpha-inducible inflammatory genes by interferon-gamma is associated with altered nuclear factor-kappaB transactivation and enhanced histone deacetylase activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

1 September 2018

Airway smooth muscle and mast cell-derived CC chemokine ligand 19 mediate airway smooth muscle migration in asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

1 September 2018

Regulation of TNF-alpha- and IFN-gamma-induced CXCL10 expression: participation of the airway smooth muscle in the pulmonary inflammatory response in chronic obstructive pulmonary disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

1 September 2018

Heterogeneity of airway inflammation in persistent asthma : evidence of neutrophilic inflammation and increased sputum interleukin-8.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

1 September 2018

Regulation of TNF-alpha-induced eotaxin release from cultured human airway smooth muscle cells by beta2-agonists and corticosteroids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

1 September 2018

Tumor necrosis factor-alpha-induced secretion of RANTES and interleukin-6 from human airway smooth-muscle cells. Modulation by cyclic adenosine monophosphate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

1 September 2018

Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

1 September 2018

The CXCL10/CXCR3 Axis Mediates Human Lung Mast Cell Migration to Asthmatic Airway Smooth Muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992371

1 September 2018

Neutrophilic inflammation in severe persistent asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19734226

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergistic inhibition by beta(2)-agonists and corticosteroids on tumor necrosis factor-alpha-induced interleukin-8 release from cultured human airway smooth-muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19734226

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TGF-beta1 stimulates IL-8 release, COX-2 expression, and PGE(2) release in human airway smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19734226

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sudden-onset fatal asthma. A distinct entity with few eosinophils and relatively more neutrophils in the airway submucosa?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19734226

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanism of interleukin-8 gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/19734226

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prominent neutrophilic inflammation in sputum from subjects with asthma exacerbation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19734226

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human airway smooth muscle cells express and release RANTES in response to T helper 1 cytokines: regulation by T helper 2 cytokines and corticosteroids

1 reference

https://pubmed.ncbi.nlm.nih.gov/19734226

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bronchoscopic evaluation of severe asthma. Persistent inflammation associated with high dose glucocorticoids

1 reference

https://pubmed.ncbi.nlm.nih.gov/19734226

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bronchial neutrophilia in patients with noninfectious status asthmaticus

1 reference

https://pubmed.ncbi.nlm.nih.gov/19734226

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lung function and sputum characteristics of patients with severe asthma during an induced exacerbation by double-blind steroid withdrawal

1 reference

https://pubmed.ncbi.nlm.nih.gov/19734226

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CXC chemokines in angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19734226

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular Matrix Regulates Enhanced Eotaxin Expression in Asthmatic Airway Smooth Muscle Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19734226

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.0803832

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

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