(Q34505890)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26687007%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

title

Targeting senescent cells enhances adipogenesis and metabolic function in old age (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26687007%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26687007%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Allyson Palmer

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26687007%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Nathan K. LeBrasseur

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26687007%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

author name string

Husheng Ding

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26687007%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Megan M Weivoda

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26687007%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Tamar Pirtskhalava

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26687007%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Thomas A White

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26687007%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Anna Sepe

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26687007%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Kurt O Johnson

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26687007%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Michael B Stout

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26687007%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Nino Giorgadze

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26687007%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Michael D Jensen

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26687007%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Tamar Tchkonia

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26687007%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

James L Kirkland

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26687007%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

language of work or name

English

0 references

publication date

19 December 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26687007%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26687007%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

volume

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26687007%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

page(s)

e12997

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26687007%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

3 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4758946/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.

7 July 2018

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Insulin resistance and impaired adipogenesis

7 July 2018

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Growth hormone action predicts age-related white adipose tissue dysfunction and senescent cell burden in mice.

7 July 2018

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A complex secretory program orchestrated by the inflammasome controls paracrine senescence

7 July 2018

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The role of JAK-STAT signaling in adipose tissue function

7 July 2018

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Mechanisms and metabolic implications of regional differences among fat depots

7 July 2018

1 reference

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Perilipin1 promotes unilocular lipid droplet formation through the activation of Fsp27 in adipocytes

7 July 2018

1 reference

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Cellular senescence and the senescent secretory phenotype: therapeutic opportunities

7 July 2018

1 reference

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Effects of the activin A-myostatin-follistatin system on aging bone and muscle progenitor cells

7 July 2018

1 reference

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Cell autonomous lipin 1 function is essential for development and maintenance of white and brown adipose tissue

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

The intersection between aging and cardiovascular disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

A double-blind, placebo-controlled trial of ruxolitinib for myelofibrosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

JAK inhibition with ruxolitinib versus best available therapy for myelofibrosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

A senescent cell bystander effect: senescence-induced senescence

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

Ncb5or deficiency increases fatty acid catabolism and oxidative stress

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

Obesity, insulin resistance and free fatty acids

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

Regional differences in cellular mechanisms of adipose tissue gain with overfeeding

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

Fat tissue, aging, and cellular senescence

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

Activin a plays a critical role in proliferation and differentiation of human adipose progenitors

7 July 2018

1 reference

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Characterization of the ligand binding functionality of the extracellular domain of activin receptor type IIb.

7 July 2018

1 reference

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Gluttony, sloth and the metabolic syndrome: a roadmap to lipotoxicity

7 July 2018

1 reference

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A human-like senescence-associated secretory phenotype is conserved in mouse cells dependent on physiological oxygen

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

Aging, depot origin, and preadipocyte gene expression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

Interferon gamma attenuates insulin signaling, lipid storage, and differentiation in human adipocytes via activation of the JAK/STAT pathway.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

The structure of myostatin:follistatin 288: insights into receptor utilization and heparin binding

7 July 2018

1 reference

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7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

The biology of activin: recent advances in structure, regulation and function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

Saturated with fat: new perspectives on lipotoxicity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

Dynamics of fat cell turnover in humans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

Adipogenic capacity and the susceptibility to type 2 diabetes and metabolic syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

Adipose tissue lipin-1 expression is correlated with peroxisome proliferator-activated receptor alpha gene expression and insulin sensitivity in healthy young men.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

Increased TNFalpha and CCAAT/enhancer-binding protein homologous protein with aging predispose preadipocytes to resist adipogenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

Transgenic expression of a myostatin inhibitor derived from follistatin increases skeletal muscle mass and ameliorates dystrophic pathology in mdx mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

Cellular senescence: when bad things happen to good cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

Aging in adipocytes: potential impact of inherent, depot-specific mechanisms

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

Lipotoxicity, overnutrition and energy metabolism in aging

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

Cytokines promote Wnt signaling and inflammation and impair the normal differentiation and lipid accumulation in 3T3-L1 preadipocytes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

Increased caveolin-1, a cause for the declined adipogenic potential of senescent human mesenchymal stem cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

Regulation of muscle mass by myostatin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

The serial cultivation of human diploid cell strains

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

Triglyceride accumulation protects against fatty acid-induced lipotoxicity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

Suppression of body fat accumulation in myostatin-deficient mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

Reconstitution of insulin-sensitive glucose transport in fibroblasts requires expression of both PPARgamma and C/EBPalpha.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

Intracellular lipid-binding proteins and their genes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

CCAAT/enhancer binding protein alpha is sufficient to initiate the 3T3-L1 adipocyte differentiation program

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

Mechanisms of Insulin Resistance in Aging

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

Age, anatomic site, and the replication and differentiation of adipocyte precursors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

Prevalence of diabetes and impaired fasting glucose in adults in the U.S. population: National Health And Nutrition Examination Survey 1999-2002.

7 July 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.12997

Adipogenic differentiation is impaired in replicative senescent human subcutaneous adipose-derived stromal/progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.12997

White-to-brown metabolic conversion of human adipocytes by JAK inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.12997

Cross-regulation of C/EBP alpha and PPAR gamma controls the transcriptional pathway of adipogenesis and insulin sensitivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.12997

Adipogenesis of the mesenchymal stromal cells and bone oedema in rheumatoid arthritis.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

Altered expression of C/EBP family members results in decreased adipogenesis with aging

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758946

Abundance of two human preadipocyte subtypes with distinct capacities for replication, adipogenesis, and apoptosis varies among fat depots

27 October 2018

1 reference

12 December 2020

A 3-year longitudinal study on body composition changes in the elderly: role of physical exercise

1 reference

12 December 2020

Increased CUG triplet repeat-binding protein-1 predisposes to impaired adipogenesis with aging

1 reference

12 December 2020

Aging results in paradoxical susceptibility of fat cell progenitors to lipotoxicity

1 reference

12 December 2020

Identifiers

DOI

10.7554/ELIFE.12997

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26687007%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26687007%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference