(Q34507561)

2 August 2017

Prospects for gene-engineered T cell immunotherapy for solid cancers (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6295670&resulttype=core&format=json

13 May 2020

1 reference

Christopher A. Klebanoff

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6295670&resulttype=core&format=json

13 May 2020

Nicholas P. Restifo

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6295670&resulttype=core&format=json

13 May 2020

2

Steven A Rosenberg

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6295670&resulttype=core&format=json

13 May 2020

language of work or name

English

0 references

publication date

1 January 2016

1 reference

2 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6295670&resulttype=core&format=json

13 May 2020

volume

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6295670&resulttype=core&format=json

13 May 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6295670&resulttype=core&format=json

13 May 2020

page(s)

26-36

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6295670&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nm.4015

13 May 2020

exact match

0 references

cites work

Immunogenicity of induced pluripotent stem cells

1 reference

12 December 2020

CD8+CD103+ tumor-infiltrating lymphocytes are tumor-specific tissue-resident memory T cells and a prognostic factor for survival in lung cancer patients

1 reference

12 December 2020

Bystander elimination of antigen loss variants in established tumors

1 reference

12 December 2020

Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy

1 reference

12 December 2020

Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19.

1 reference

12 December 2020

A phase I clinical trial of adoptive T cell therapy using IL-12 secreting MUC-16(ecto) directed chimeric antigen receptors for recurrent ovarian cancer

1 reference

12 December 2020

Generation of peptide–MHC class I complexes through UV-mediated ligand exchange

1 reference

12 December 2020

Current concepts in the diagnosis and management of cytokine release syndrome

1 reference

12 December 2020

Natural selection of tumor variants in the generation of "tumor escape" phenotypes

1 reference

12 December 2020

Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer

1 reference

12 December 2020

Serological analysis of Melan-A(MART-1), a melanocyte-specific protein homogeneously expressed in human melanomas

1 reference

12 December 2020

Negligible immunogenicity of terminally differentiated cells derived from induced pluripotent or embryonic stem cells

1 reference

12 December 2020

Efficient identification of mutated cancer antigens recognized by T cells associated with durable tumor regressions.

1 reference

12 December 2020

Human CD38: a glycoprotein in search of a function

1 reference

12 December 2020

Characterization of a human B lymphocyte-specific antigen.

1 reference

12 December 2020

CD137 accurately identifies and enriches for naturally occurring tumor-reactive T cells in tumor.

1 reference

12 December 2020

NY-ESO-1-specific TCR-engineered T cells mediate sustained antigen-specific antitumor effects in myeloma.

1 reference

12 December 2020

Chimeric antigen receptor T cells for sustained remissions in leukemia

1 reference

12 December 2020

4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors

1 reference

12 December 2020

HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia

1 reference

12 December 2020

Safety and Antitumor Activity of Anti-PD-1 Antibody, Nivolumab, in Patients With Platinum-Resistant Ovarian Cancer

1 reference

12 December 2020

Generation of rejuvenated antigen-specific T cells by reprogramming to pluripotency and redifferentiation

1 reference

12 December 2020

PD-1 blockade induces responses by inhibiting adaptive immune resistance

1 reference

12 December 2020

T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis.

1 reference

12 December 2020

Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains.

1 reference

12 December 2020

A transgene-encoded cell surface polypeptide for selection, in vivo tracking, and ablation of engineered cells

1 reference

12 December 2020

Allele frequency net: a database and online repository for immune gene frequencies in worldwide populations

1 reference

12 December 2020

Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias

1 reference

12 December 2020

Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer

1 reference

12 December 2020

Safety, activity, and immune correlates of anti-PD-1 antibody in cancer

1 reference

12 December 2020

Cancer immunotherapy based on mutation-specific CD4+ T cells in a patient with epithelial cancer

1 reference

12 December 2020

Cell transfer immunotherapy for metastatic solid cancer--what clinicians need to know.

1 reference

12 December 2020

Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia

1 reference

12 December 2020

Human Epidermal Growth Factor Receptor 2 (HER2) -Specific Chimeric Antigen Receptor-Modified T Cells for the Immunotherapy of HER2-Positive Sarcoma

1 reference

12 December 2020

Expression of the HER-2/neu proto-oncogene in normal human adult and fetal tissues

1 reference

12 December 2020

Mechanisms of action of therapeutic antibodies for cancer

1 reference

12 December 2020

Treatment of metastatic melanoma with autologous CD4+ T cells against NY-ESO-1

1 reference

12 December 2020

Multiple injections of electroporated autologous T cells expressing a chimeric antigen receptor mediate regression of human disseminated tumor

1 reference

12 December 2020

Multiplexed gene transfer to a human T-cell line by combining Sleeping Beauty transposon system with methotrexate selection

1 reference

12 December 2020

PD-1- and CTLA-4-based inhibitory chimeric antigen receptors (iCARs) divert off-target immunotherapy responses

1 reference

12 December 2020

Two-photon imaging of intratumoral CD8+ T cell cytotoxic activity during adoptive T cell therapy in mice

1 reference

12 December 2020

Universal artificial antigen presenting cells to selectively propagate T cells expressing chimeric antigen receptor independent of specificity

1 reference

12 December 2020

An inducible caspase 9 safety switch for T-cell therapy

1 reference

12 December 2020

Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2

1 reference

12 December 2020

CD30 is a signal-transducing molecule that defines a subset of human activated CD45RO+ T cells

1 reference

12 December 2020

Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy

1 reference

12 December 2020

Chimeric Antigen Receptor T Cells against CD19 for Multiple Myeloma

1 reference

12 December 2020

A pilot trial using lymphocytes genetically engineered with an NY-ESO-1-reactive T-cell receptor: long-term follow-up and correlates with response

1 reference

12 December 2020

Dissection of T-cell Antigen Specificity in Human Melanoma

1 reference

12 December 2020

Identification of chimeric antigen receptors that mediate constitutive or inducible proliferation of T cells

1 reference

12 December 2020

Lack of immune response to differentiated cells derived from syngeneic induced pluripotent stem cells

1 reference

12 December 2020

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

1 reference

12 December 2020

B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells

1 reference

12 December 2020

CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia

1 reference

12 December 2020

Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma.

1 reference

12 December 2020

Rational development and characterization of humanized anti-EGFR variant III chimeric antigen receptor T cells for glioblastoma

1 reference

12 December 2020

Therapeutic cancer vaccines: are we there yet?

1 reference

12 December 2020

Replication-competent retroviruses in gene-modified T cells used in clinical trials: is it time to revise the testing requirements?

1 reference

12 December 2020

Somatic mutation in cancer and normal cells

1 reference

12 December 2020

Myeloid-associated differentiation antigens on stem cells and their progeny identified by monoclonal antibodies

1 reference

12 December 2020

Remote control of therapeutic T cells through a small molecule-gated chimeric receptor.

1 reference

12 December 2020

Combinatorial antigen recognition with balanced signaling promotes selective tumor eradication by engineered T cells

1 reference

12 December 2020

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

1 reference

12 December 2020

ErbB2 is essential in the prevention of dilated cardiomyopathy.

1 reference

12 December 2020

PD-1 blockade with nivolumab in relapsed or refractory Hodgkin's lymphoma

1 reference

12 December 2020

Chimeric antigen receptor-modified T cells for acute lymphoid leukemia

1 reference

12 December 2020

Therapeutic genome editing: prospects and challenges

1 reference

12 December 2020

Characterization of an antigen that is recognized on a melanoma showing partial HLA loss by CTL expressing an NK inhibitory receptor

1 reference

12 December 2020

Nivolumab versus Everolimus in Advanced Renal-Cell Carcinoma

1 reference

12 December 2020

Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia

1 reference

12 December 2020

Inducible apoptosis as a safety switch for adoptive cell therapy

1 reference

12 December 2020

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

1 reference

12 December 2020

High-throughput identification of antigen-specific TCRs by TCR gene capture

1 reference

12 December 2020

Expression profiling of TCR-engineered T cells demonstrates overexpression of multiple inhibitory receptors in persisting lymphocytes

1 reference

12 December 2020

High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma

1 reference

12 December 2020

Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells

1 reference

12 December 2020

Treatment of metastatic renal cell carcinoma with autologous T-lymphocytes genetically retargeted against carbonic anhydrase IX: first clinical experience

1 reference

12 December 2020

Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the gamma or zeta subunits of the immunoglobulin and T-cell receptors

1 reference

12 December 2020

Reprogramming antitumor immunity

1 reference

12 December 2020

Sorting through subsets: which T-cell populations mediate highly effective adoptive immunotherapy?

1 reference

12 December 2020

T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial

1 reference

12 December 2020

Sustained complete responses in patients with lymphoma receiving autologous cytotoxic T lymphocytes targeting Epstein-Barr virus latent membrane proteins

1 reference

12 December 2020

Determinants of successful CD8+ T-cell adoptive immunotherapy for large established tumors in mice

1 reference

12 December 2020

Reassessing target antigens for adoptive T-cell therapy

1 reference

12 December 2020

Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia

1 reference

12 December 2020

Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1

1 reference

12 December 2020

Complete regression of metastatic cervical cancer after treatment with human papillomavirus-targeted tumor-infiltrating T cells.

1 reference

12 December 2020

Antigen spreading contributes to MAGE vaccination-induced regression of melanoma metastases

1 reference

12 December 2020

Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy

1 reference

12 December 2020

Identification of a Titin-derived HLA-A1-presented peptide as a cross-reactive target for engineered MAGE A3-directed T cells

1 reference

12 December 2020

PD-1 identifies the patient-specific CD8⁺ tumor-reactive repertoire infiltrating human tumors

1 reference

12 December 2020

Regional delivery of mesothelin-targeted CAR T cell therapy generates potent and long-lasting CD4-dependent tumor immunity

1 reference

12 December 2020

Rapid production of clinical-grade gammaretroviral vectors in expanded surface roller bottles using a "modified" step-filtration process for clearance of packaging cells

1 reference

12 December 2020

Long-term outcome after haploidentical stem cell transplant and infusion of T cells expressing the inducible caspase 9 safety transgene

1 reference

12 December 2020

A phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer

1 reference

12 December 2020

Regeneration of human tumor antigen-specific T cells from iPSCs derived from mature CD8(+) T cells

1 reference

12 December 2020

Cancer statistics, 2015

1 reference

12 December 2020

Tumorigenicity as a clinical hurdle for pluripotent stem cell therapies

1 reference

12 December 2020

Adoptive cell transfer as personalized immunotherapy for human cancer

1 reference

12 December 2020

Isolation of neoantigen-specific T cells from tumor and peripheral lymphocytes

1 reference

12 December 2020

Comparison of lentiviral and sleeping beauty mediated αβ T cell receptor gene transfer

1 reference

12 December 2020

Paths to stemness: building the ultimate antitumour T cell.

1 reference

12 December 2020

Cish actively silences TCR signaling in CD8+ T cells to maintain tumor tolerance

1 reference

12 December 2020

MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer

1 reference

12 December 2020

MUC16: molecular analysis and its functional implications in benign and malignant conditions

1 reference

12 December 2020

Anti-PD-1 antibody therapy potently enhances the eradication of established tumors by gene-modified T cells

1 reference

12 December 2020

Tumor exome analysis reveals neoantigen-specific T-cell reactivity in an ipilimumab-responsive melanoma

1 reference

12 December 2020

Pluripotency and cellular reprogramming: facts, hypotheses, unresolved issues

1 reference

12 December 2020

CD3 limits the efficacy of TCR gene therapy in vivo

1 reference

12 December 2020

Generation of tumor-targeted human T lymphocytes from induced pluripotent stem cells for cancer therapy

1 reference

12 December 2020

Targeting of HPV-16+ Epithelial Cancer Cells by TCR Gene Engineered T Cells Directed against E6

1 reference

12 December 2020

Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma

1 reference

12 December 2020

Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor

1 reference

12 December 2020

Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma

1 reference

12 December 2020

Discovery of mesothelin and exploiting it as a target for immunotherapy

1 reference

12 December 2020

Genomic correlates of response to CTLA-4 blockade in metastatic melanoma

1 reference

12 December 2020

Immunohistochemical analysis of NY-ESO-1 antigen expression in normal and malignant human tissues

1 reference

12 December 2020

Nivolumab versus Docetaxel in Advanced Squamous-Cell Non-Small-Cell Lung Cancer

1 reference

12 December 2020

Decade-long safety and function of retroviral-modified chimeric antigen receptor T cells

1 reference

12 December 2020

Redirecting specificity of T-cell populations for CD19 using the Sleeping Beauty system

1 reference

12 December 2020

Human peripheral blood mononuclear cells exhibit heterogeneous CD52 expression levels and show differential sensitivity to alemtuzumab mediated cytolysis

1 reference

12 December 2020

Recognition of glioma stem cells by genetically modified T cells targeting EGFRvIII and development of adoptive cell therapy for glioma

1 reference

12 December 2020

Neoantigens in cancer immunotherapy.

1 reference

12 December 2020

Tumor-specific activation of an EGFR-targeting probody enhances therapeutic index

1 reference

12 December 2020

Continuous cultures of fused cells secreting antibody of predefined specificity

1 reference

12 December 2020

IL-12 triggers a programmatic change in dysfunctional myeloid-derived cells within mouse tumors.

1 reference

12 December 2020

Immunogenetics of human cell surface differentiation

1 reference

12 December 2020

Immunogenicity of somatic mutations in human gastrointestinal cancers.

1 reference

12 December 2020

Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA

1 reference

12 December 2020

Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor

1 reference

12 December 2020

A TCR targeting the HLA-A*0201-restricted epitope of MAGE-A3 recognizes multiple epitopes of the MAGE-A antigen superfamily in several types of cancer.

1 reference

12 December 2020

Genetic basis for clinical response to CTLA-4 blockade in melanoma

1 reference

12 December 2020

PD-1 Blockade in Tumors with Mismatch-Repair Deficiency

1 reference

12 December 2020

Sipuleucel-T immunotherapy for castration-resistant prostate cancer

1 reference

12 December 2020

High-throughput pairing of T cell receptor α and β sequences

1 reference

12 December 2020

Cancer/testis (CT) antigens: potential targets for immunotherapy

1 reference

12 December 2020

Structural alterations of the epidermal growth factor receptor gene in human gliomas

1 reference

12 December 2020

A new approach to gene therapy using Sleeping Beauty to genetically modify clinical-grade T cells to target CD19

1 reference

12 December 2020

Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen

1 reference

12 December 2020

Clinical-scale selection and viral transduction of human naïve and central memory CD8+ T cells for adoptive cell therapy of cancer patients.

1 reference

12 December 2020

Novel serial positive enrichment technology enables clinical multiparameter cell sorting

1 reference

12 December 2020

T cell receptor αβ diversity inversely correlates with pathogen-specific antibody levels in human cytomegalovirus infection

1 reference

12 December 2020

T-cell mediated rejection of gene-modified HIV-specific cytotoxic T lymphocytes in HIV-infected patients

1 reference

12 December 2020

Abstract CT105: Safety and feasibility of chimeric antigen receptor modified T cells directed against mesothelin (CART-meso) in patients with mesothelin expressing cancers

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNM.4015

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NM.4015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6295670&resulttype=core&format=json

Dimensions Publication ID

13 May 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6295670&resulttype=core&format=json

13 May 2020

1 reference