(Q34509576)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21078677%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

PLK1 phosphorylates mitotic centromere-associated kinesin and promotes its depolymerase activity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21078677%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21078677%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Chuanhai Fu

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21078677%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

author name string

Hengyi Shao

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21078677%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Yuejia Huang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21078677%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Feng Yan

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21078677%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Youjun Chu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21078677%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Hai Hou

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21078677%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Mei Zhu

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21078677%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Felix Aikhionbare

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21078677%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Guowei Fang

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21078677%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Xia Ding

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21078677%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Xuebiao Yao

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21078677%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

language of work or name

English

0 references

publication date

15 November 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21078677%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

16 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21078677%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

volume

286

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21078677%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21078677%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

page(s)

3033-3046

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21078677%20AND%20SRC:MED&resulttype=core&format=json

Aurora B kinase activation requires survivin priming phosphorylation by PLK1.

16 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

Probing CENP-E function in chromosome dynamics using small molecule inhibitor syntelin.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

Functional and spatial regulation of mitotic centromere-associated kinesin by cyclin-dependent kinase 1.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

Catalysis of the microtubule on-rate is the major parameter regulating the depolymerase activity of MCAK.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

PRC1 cooperates with CLASP1 to organize central spindle plasticity in mitosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

TIP150 interacts with and targets MCAK at the microtubule plus ends

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

Genome stability is ensured by temporal control of kinetochore-microtubule dynamics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

Polo on the Rise-from Mitotic Entry to Cytokinesis with Plk1.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

Aurora A phosphorylates MCAK to control ran-dependent spindle bipolarity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

MCAK facilitates chromosome movement by promoting kinetochore microtubule turnover

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

Involvement of kinesin family member 2C/mitotic centromere-associated kinesin overexpression in mammary carcinogenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

Clinicopathological and biological significance of mitotic centromere-associated kinesin overexpression in human gastric cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

Phospho-regulation of HsCdc14A By Polo-like kinase 1 is essential for mitotic progression.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

Aurora B phosphorylates multiple sites on mitotic centromere-associated kinesin to spatially and temporally regulate its function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

The kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

Tripin/hSgo2 recruits MCAK to the inner centromere to correct defective kinetochore attachments

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

The interplay of the N- and C-terminal domains of MCAK control microtubule depolymerization activity and spindle assembly

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

Self-regulated Plk1 recruitment to kinetochores by the Plk1-PBIP1 interaction is critical for proper chromosome segregation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

Aurora B is enriched at merotelic attachment sites, where it regulates MCAK.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

Full-length dimeric MCAK is a more efficient microtubule depolymerase than minimal domain monomeric MCAK

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

Efficient mitosis in human cells lacking poleward microtubule flux

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

MCAK associates with the tips of polymerizing microtubules

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

CaMKIIgamma-mediated inactivation of the Kin I kinesin MCAK is essential for bipolar spindle formation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

Functionally distinct kinesin-13 family members cooperate to regulate microtubule dynamics during interphase.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

Polo-like kinases and oncogenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

A standardized kinesin nomenclature

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

Mechanisms and molecules of the mitotic spindle

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

MCAK, a Kin I kinesin, increases the catastrophe frequency of steady-state HeLa cell microtubules in an ATP-dependent manner in vitro

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

The KinI kinesin Kif2a is required for bipolar spindle assembly through a functional relationship with MCAK

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

The chromosomal passenger complex is required for chromatin-induced microtubule stabilization and spindle assembly

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

Differentiation of cytoplasmic and meiotic spindle assembly MCAK functions by Aurora B-dependent phosphorylation.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

A common mechanism for microtubule destabilizers-M type kinesins stabilize curling of the protofilament using the class-specific neck and loops

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

Aurora B phosphorylates centromeric MCAK and regulates its localization and microtubule depolymerization activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

Aurora B regulates MCAK at the mitotic centromere

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

Differential functional interplay of TOGp/XMAP215 and the KinI kinesin MCAK during interphase and mitosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

TOGp, the human homolog of XMAP215/Dis1, is required for centrosome integrity, spindle pole organization, and bipolar spindle assembly

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

Depletion of centromeric MCAK leads to chromosome congression and segregation defects due to improper kinetochore attachments

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

The microtubule-destabilizing kinesin XKCM1 regulates microtubule dynamic instability in cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

Molecular dissection of the microtubule depolymerizing activity of mitotic centromere-associated kinesin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

CENP-E forms a link between attachment of spindle microtubules to kinetochores and the mitotic checkpoint

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

Control of microtubule dynamics by the antagonistic activities of XMAP215 and XKCM1 in Xenopus egg extracts

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

Mitotic centromere-associated kinesin is important for anaphase chromosome segregation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

XKCM1: a Xenopus kinesin-related protein that regulates microtubule dynamics during mitotic spindle assembly

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

Induction and down-regulation of PLK, a human serine/threonine kinase expressed in proliferating cells and tumors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

Identification and partial characterization of mitotic centromere-associated kinesin, a kinesin-related protein that associates with centromeres during mitosis

7 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

7 July 2018

https://pubmed.ncbi.nlm.nih.gov/21078677

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

polo, a mitotic mutant of Drosophila displaying abnormal spindle poles.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

Kin I kinesins are microtubule-destabilizing enzymes

7 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.165340

A mechanism for microtubule depolymerization by KinI kinesins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.165340

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.165340

Aurora-A and ch-TOG act in a common pathway in control of spindle pole integrity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.165340

An inner centromere protein that stimulates the microtubule depolymerizing activity of a KinI kinesin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.165340

Targeting polo-like kinase 1 for cancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.165340

Plk1 and Aurora A regulate the depolymerase activity and the cellular localization of Kif2a

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.165340

Comprehensive and reliable phosphorylation site mapping of individual phosphoproteins by combination of multiple stage mass spectrometric analysis with a target-decoy database search.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.165340

The Plk1-dependent phosphoproteome of the early mitotic spindle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.165340

Cloning and characterization of human and murine homologues of the Drosophila polo serine-threonine kinase.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024797

27 October 2018

Identifiers

DOI

10.1074/JBC.M110.165340

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21078677%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21078677%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

PubMed publication ID

21078677

1 reference