(Q34509729)

2 August 2017

title

Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria (English)

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2 August 2017

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7

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2 August 2017

Pedro M Quirós

6

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Carsten Merkwirth

object named as

Carsten Merkwirth

2

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Elena I Rugarli

object named as

Elena I Rugarli

8

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author name string

Anne Korwitz

1

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2 August 2017

Ricarda Richter-Dennerlein

3

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2 August 2017

Simon E Tröder

4

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2 August 2017

Hans-Georg Sprenger

5

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2 August 2017

Thomas Langer

9

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2 August 2017

language of work or name

English

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publication date

1 January 2016

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2 August 2017

published in

Journal of Cell Biology

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2 August 2017

volume

212

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2 August 2017

issue

2

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2 August 2017

page(s)

157-166

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describes a project that uses

2 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4738383/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Opa1 overexpression ameliorates the phenotype of two mitochondrial disease mouse models.

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The OPA1-dependent mitochondrial cristae remodeling pathway controls atrophic, apoptotic, and ischemic tissue damage

7 July 2018

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New roles for mitochondrial proteases in health, ageing and disease

7 July 2018

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Synaptic dysfunction, memory deficits and hippocampal atrophy due to ablation of mitochondrial fission in adult forebrain neurons

7 July 2018

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7 July 2018

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7 July 2018

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C11orf83, a mitochondrial cardiolipin-binding protein involved in bc1 complex assembly and supercomplex stabilization

7 July 2018

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7 July 2018

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OPA1-dependent cristae modulation is essential for cellular adaptation to metabolic demand

7 July 2018

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Activation of mitochondrial protease OMA1 by Bax and Bak promotes cytochrome c release during apoptosis

7 July 2018

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7 July 2018

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7 July 2018

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DNAJC19, a mitochondrial cochaperone associated with cardiomyopathy, forms a complex with prohibitins to regulate cardiolipin remodeling

7 July 2018

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Membrane depolarization activates the mitochondrial protease OMA1 by stimulating self-cleavage

7 July 2018

1 reference

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Proteolytic cleavage of Opa1 stimulates mitochondrial inner membrane fusion and couples fusion to oxidative phosphorylation

7 July 2018

1 reference

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OMA1 mediates OPA1 proteolysis and mitochondrial fragmentation in experimental models of ischemic kidney injury

7 July 2018

1 reference

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The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission

7 July 2018

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Stress-induced OMA1 activation and autocatalytic turnover regulate OPA1-dependent mitochondrial dynamics

7 July 2018

1 reference

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Mitochondrial form and function

7 July 2018

1 reference

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Mitochondria: a kinase anchoring protein 1, a signaling platform for mitochondrial form and function

7 July 2018

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Cardiolipin remodeling and the function of tafazzin

7 July 2018

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Loss of prohibitin membrane scaffolds impairs mitochondrial architecture and leads to tau hyperphosphorylation and neurodegeneration

7 July 2018

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AFG3L2 supports mitochondrial protein synthesis and Purkinje cell survival

7 July 2018

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Mitochondrial fission, fusion, and stress

7 July 2018

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Mitochondrial dynamics in cardiovascular health and disease

7 July 2018

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Mitochondrial nucleoid interacting proteins support mitochondrial protein synthesis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4738383

Loss of mitochondrial protease OMA1 alters processing of the GTPase OPA1 and causes obesity and defective thermogenesis in mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4738383

YME1L controls the accumulation of respiratory chain subunits and is required for apoptotic resistance, cristae morphogenesis, and cell proliferation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4738383

Inflammation in the early stages of neurodegenerative pathology

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4738383

Making heads or tails of phospholipids in mitochondria

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4738383

Regulation of OPA1 processing and mitochondrial fusion by m-AAA protease isoenzymes and OMA1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4738383

Inducible proteolytic inactivation of OPA1 mediated by the OMA1 protease in mammalian cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4738383

Prohibitins and the functional compartmentalization of mitochondrial membranes.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4738383

SLP-2 is required for stress-induced mitochondrial hyperfusion

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4738383

Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4738383

Characterization of OPA1 isoforms isolated from mouse tissues

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4738383

Prohibitins control cell proliferation and apoptosis by regulating OPA1-dependent cristae morphogenesis in mitochondria

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4738383

Reversible phosphorylation of Drp1 by cyclic AMP-dependent protein kinase and calcineurin regulates mitochondrial fission and cell death

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4738383

Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavage

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4738383

OPA1 processing controls mitochondrial fusion and is regulated by mRNA splicing, membrane potential, and Yme1L.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4738383

Mitochondrial inner-membrane fusion and crista maintenance requires the dynamin-related GTPase Mgm1.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4738383

OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4738383

Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4738383

Regulation of mitochondrial morphology through proteolytic cleavage of OPA1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4738383

Formation of membrane-bound ring complexes by prohibitins in mitochondria

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4738383

OPA1 requires mitofusin 1 to promote mitochondrial fusion

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4738383

Cardiolipin stabilizes respiratory chain supercomplexes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4738383

Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4738383

Human prohibitin 1 maintains the organization and stability of the mitochondrial nucleoids

7 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1083%2FJCB.201507022

Quantification of muscle mitochondrial oxidative phosphorylation enzymes via histochemical staining of blue native polyacrylamide gels.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1083%2FJCB.201507022

21 January 2018

Identifiers

DOI

10.1083/JCB.201507022

1 reference

2 August 2017

1 reference

2 August 2017

1 reference