(Q34509759)

2 August 2017

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title

Role of apoe/Abeta interactions in the pathogenesis of Alzheimer's disease and cerebral amyloid angiopathy (English)

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2 August 2017

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1

Holtzman DM

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2 August 2017

1 October 2001

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Journal of Molecular Neuroscience

2 August 2017

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2 August 2017

17

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2 August 2017

2

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2 August 2017

147-155

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https://scigraph.springernature.com/pub.10.1385/jmn:17:2:147

2 August 2017

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cites work

Structural neurology: are seeds at the root of neuronal degeneration?

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12 December 2020

Detection of apolipoprotein E/dimeric soluble amyloid beta complexes in Alzheimer's disease brain supernatants.

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12 December 2020

The soluble form of Alzheimer's amyloid beta protein is complexed to high density lipoprotein 3 and very high density lipoprotein in normal human plasma

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12 December 2020

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

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12 December 2020

Apolipoprotein E isoform-specific reduction of extracellular amyloid in neuronal cultures.

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12 December 2020

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

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12 December 2020

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

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12 December 2020

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

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12 December 2020

Structure and functions of human cerebrospinal fluid lipoproteins from individuals of different APOE genotypes

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12 December 2020

Association of apolipoprotein E epsilon2 and vasculopathy in cerebral amyloid angiopathy

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12 December 2020

Amyloid A4 protein and its precursor in Down's syndrome and Alzheimer's disease.

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12 December 2020

Purification of apolipoprotein E attenuates isoform-specific binding to beta-amyloid

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12 December 2020

Is Alzheimer's disease an apolipoprotein E amyloidosis?

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12 December 2020

Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition.

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12 December 2020

The apolipoprotein epsilon 4 allele in patients with Alzheimer's disease

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12 December 2020

Astrocytes and microglia respond to estrogen with increased apoE mRNA in vivo and in vitro

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12 December 2020

Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier

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12 December 2020

Interaction of nascent ApoE2, ApoE3, and ApoE4 isoforms expressed in mammalian cells with amyloid peptide beta (1-40). Relevance to Alzheimer's disease.

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12 December 2020

Apolipoprotein E and the apolipoprotein E-deficient mouse

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12 December 2020

Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease

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12 December 2020

Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro

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12 December 2020

Expression of human apolipoprotein E3 or E4 in the brains of Apoe-/- mice: isoform-specific effects on neurodegeneration.

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12 December 2020

Apolipoprotein E-epsilon4 alleles in cerebral amyloid angiopathy and cerebrovascular pathology associated with Alzheimer's disease

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12 December 2020

Fate of cerebrospinal fluid-borne amyloid beta-peptide: rapid clearance into blood and appreciable accumulation by cerebral arteries.

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12 December 2020

Apolipoprotein E and cognitive performance

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12 December 2020

Lipoprotein-free amyloidogenic peptides in plasma are elevated in patients with sporadic Alzheimer's disease and Down's syndrome.

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12 December 2020

Expression of the very low-density lipoprotein receptor (VLDL-r), an apolipoprotein-E receptor, in the central nervous system and in Alzheimer's disease.

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12 December 2020

Localization of mRNA for low density lipoprotein receptor and a cholesterol synthetic enzyme in rabbit nervous system by in situ hybridization

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12 December 2020

Molecular characterization of a novel human hybrid-type receptor that binds the alpha2-macroglobulin receptor-associated protein

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12 December 2020

Characterization of the binding of amyloid-beta peptide to cell culture-derived native apolipoprotein E2, E3, and E4 isoforms and to isoforms from human plasma

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12 December 2020

Alzheimer's beta-amyloid peptide is conformationally modified by apolipoprotein E in vitro.

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12 December 2020

Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system

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12 December 2020

Biochemical characterization of Alzheimer's soluble amyloid beta protein in human cerebrospinal fluid: association with high density lipoproteins

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12 December 2020

Apolipoprotein E and Alzheimer's disease

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12 December 2020

Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease

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12 December 2020

Co-expression of beta-amyloid precursor protein (betaAPP) and apolipoprotein E in cell culture: analysis of betaAPP processing

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12 December 2020

Elements of neural adhesion molecules and a yeast vacuolar protein sorting receptor are present in a novel mammalian low density lipoprotein receptor family member.

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12 December 2020

Characterization of stable complexes involving apolipoprotein E and the amyloid beta peptide in Alzheimer's disease brain.

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12 December 2020

Combined Amyloid Vascular Changes and Argyrophilic Plaques in the Central Nervous System

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12 December 2020

Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions

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12 December 2020

Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease.

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12 December 2020

ApoE genotype and Down's syndrome

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12 December 2020

Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome.

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12 December 2020

Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line

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12 December 2020

Cerebral amyloid angiopathy. A critical review

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12 December 2020

Low density lipoprotein receptor-related protein mediates uptake of cholesteryl esters derived from apoprotein E-enriched lipoproteins

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12 December 2020

Seeding of A beta fibril formation is inhibited by all three isotypes of apolipoprotein E.

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12 December 2020

Plastic neuronal remodeling is impaired in patients with Alzheimer's disease carrying apolipoprotein epsilon 4 allele

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12 December 2020

Fibrillogenesis in Alzheimer's disease of amyloid beta peptides and apolipoprotein E.

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12 December 2020

Apolipoprotein E facilitates neuritic and cerebrovascular plaque formation in an Alzheimer's disease model.

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12 December 2020

Apolipoprotein E: cholesterol transport protein with expanding role in cell biology

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12 December 2020

High frequency of apolipoprotein E ?2 Allele in hemorrhage due to cerebral amyloid angiopathy

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12 December 2020

Tangles and plaques in nondemented aging and "preclinical" Alzheimer's disease.

1 reference

12 December 2020

Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B,E(LDL) receptors in the brain.

1 reference

12 December 2020

Quantitative analysis of senile plaques in Alzheimer disease: observation of log-normal size distribution and molecular epidemiology of differences associated with apolipoprotein E genotype and trisomy 21 (Down syndrome).

1 reference

12 December 2020

Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid beta peptides

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12 December 2020

Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease

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12 December 2020

Nascent astrocyte particles differ from lipoproteins in CSF.

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12 December 2020

The interaction between apolipoprotein E and Alzheimer's amyloid beta-peptide is dependent on beta-peptide conformation

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12 December 2020

Human apolipoprotein E receptor 2. A novel lipoprotein receptor of the low density lipoprotein receptor family predominantly expressed in brain

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12 December 2020

Unique lipoproteins secreted by primary astrocytes from wild type, apoE (-/-), and human apoE transgenic mice.

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12 December 2020

Amyloid beta40/42 clearance across the blood-brain barrier following intra-ventricular injections in wild-type, apoE knock-out and human apoE3 or E4 expressing transgenic mice.

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12 December 2020

Targeted replacement of the mouse apolipoprotein E gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis

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12 December 2020

Characterization of subpopulations of lipoprotein particles isolated from human cerebrospinal fluid

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12 December 2020

Astrocytes synthesize apolipoprotein E and metabolize apolipoprotein E-containing lipoproteins

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12 December 2020

Apolipoprotein E promotes the binding and uptake of beta-amyloid into Chinese hamster ovary cells in an isoform-specific manner

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12 December 2020

Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments

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12 December 2020

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

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12 December 2020

Apolipoprotein E epsilon 4 is associated with the presence and earlier onset of hemorrhage in cerebral amyloid angiopathy

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12 December 2020

Apolipoprotein E is a kinetic but not a thermodynamic inhibitor of amyloid formation: implications for the pathogenesis and treatment of Alzheimer disease

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12 December 2020

Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3

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12 December 2020

Expression of human apolipoprotein E reduces amyloid-beta deposition in a mouse model of Alzheimer's disease

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12 December 2020

Differences in the Abeta40/Abeta42 ratio associated with cerebrospinal fluid lipoproteins as a function of apolipoprotein E genotype.

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12 December 2020

Apolipoprotein E: a pathological chaperone protein in patients with cerebral and systemic amyloid

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12 December 2020

Reduction in amyloid A amyloid formation in apolipoprotein-E-deficient mice

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12 December 2020

Dominant negative effects of apolipoprotein E4 revealed in transgenic models of neurodegenerative disease

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12 December 2020

Alzheimer's disease: genotypes, phenotypes, and treatments

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12 December 2020

Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantation

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12 December 2020

Cerebrovascular amyloidosis with cerebral hemorrhage

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12 December 2020

Isoform-specific binding of apolipoprotein E to beta-amyloid

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12 December 2020

APOE genotype and gender effects on Alzheimer disease in 100 adults with Down syndrome.

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12 December 2020

Apolipoprotein E epsilon 4 and cerebral hemorrhage associated with amyloid angiopathy

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12 December 2020

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

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12 December 2020

Identifiers

DOI

10.1385/JMN:17:2:147

1 reference

PubMed ID

11816788

Dimensions Publication ID

2 August 2017

0 references

1 reference

PubMed ID

11816788