(Q34514357)

2 August 2017

1 reference

title

Molecular pathways of protein synthesis inhibition during brain reperfusion: implications for neuronal survival or death (English)

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2 August 2017

Rita Kumar

2

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author name string

Donald J DeGracia

1

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2 August 2017

Cheri R Owen

3

1 reference

2 August 2017

Gary S Krause

4

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2 August 2017

Blaine C White

5

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2 August 2017

publication date

1 February 2002

1 reference

Journal of Cerebral Blood Flow & Metabolism

2 August 2017

published in

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2 August 2017

volume

22

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2 August 2017

issue

2

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2 August 2017

page(s)

127-141

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Changes in the phosphorylation of initiation factor eIF-2alpha, elongation factor eEF-2 and p70 S6 kinase after transient focal cerebral ischaemia in mice.

2 August 2017

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21 January 2018

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21 January 2018

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Phosphorylation of the alpha subunit of initiation factor 2 correlates with the inhibition of translation following transient cerebral ischaemia in the rat.

21 January 2018

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The intraischemic and early reperfusion changes of protein synthesis in the rat brain. eIF-2 alpha kinase activity and role of initiation factors eIF-2 alpha and eIF-4E.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Effect of brain ischemia and reperfusion on the localization of phosphorylated eukaryotic initiation factor 2 alpha

21 January 2018

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21 January 2018

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21 January 2018

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Activation of MYD116 (gadd34) expression following transient forebrain ischemia of rat: implications for a role of disturbances of endoplasmic reticulum calcium homeostasis

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Sarco(endo)plasmic reticulum Ca2+ pump isoform SERCA3 is more resistant than SERCA2b to peroxide

21 January 2018

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Correlation between protein and mRNA abundance in yeast

21 January 2018

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Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers

21 January 2018

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Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

21 January 2018

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Regulated translation initiation controls stress-induced gene expression in mammalian cells

21 January 2018

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Perk is essential for translational regulation and cell survival during the unfolded protein response

21 January 2018

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Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival

21 January 2018

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The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-

21 January 2018

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Internal ribosome entry sites in eukaryotic mRNA molecules

21 January 2018

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A novel form of DAP5 protein accumulates in apoptotic cells as a result of caspase cleavage and internal ribosome entry site-mediated translation

21 January 2018

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Mammalian GADD34, an apoptosis- and DNA damage-inducible gene

21 January 2018

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Protein aggregation after focal brain ischemia and reperfusion

21 January 2018

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Translational control by the ER transmembrane kinase/ribonuclease IRE1 under ER stress

21 January 2018

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Alterations of Akt1 (PKBalpha) and p70(S6K) in transient focal ischemia

21 January 2018

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Microarray analysis of hippocampal gene expression in global cerebral ischemia

21 January 2018

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Identification of eukaryotic mRNAs that are translated at reduced cap binding complex eIF4F concentrations using a cDNA microarray

21 January 2018

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Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

21 January 2018

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Endoplasmic reticulum stress-induced mRNA splicing permits synthesis of transcription factor Hac1p/Ern4p that activates the unfolded protein response

21 January 2018

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Protein synthesis in postischemic rat brain: a two-dimensional electrophoretic analysis

21 January 2018

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Protein synthesis in the cat brain after prolonged cerebral ischemia

21 January 2018

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The promoter region of the yeast KAR2 (BiP) gene contains a regulatory domain that responds to the presence of unfolded proteins in the endoplasmic reticulum

21 January 2018

1 reference

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Suppression of protein synthesis in the reperfused brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

Brain ischemia and reperfusion activates the eukaryotic initiation factor 2alpha kinase, PERK.

21 January 2018

1 reference

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Characterization of apoptosis-genes associated with NMDA mediated cell death in the adult rat retina

21 January 2018

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Establishment of a Chinese hamster ovary cell line that expresses grp78 antisense transcripts and suppresses A23187 induction of both GRP78 and GRP94

21 January 2018

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ATF6 as a transcription activator of the endoplasmic reticulum stress element: thapsigargin stress-induced changes and synergistic interactions with NF-Y and YY1

21 January 2018

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Increased expression of mRNA encoding calbindin-D28K, the glucose-regulated proteins, or the 72 kDa heat-shock protein in three models of acute CNS injury

21 January 2018

1 reference

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Eukaryotic translation initiation factor 4G is targeted for proteolytic cleavage by caspase 3 during inhibition of translation in apoptotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

Ischemia-induced inhibition of the initiation factor 2alpha phosphatase activity in the rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

Ectopic expression of CHOP (GADD153) induces apoptosis in M1 myeloblastic leukemia cells

21 January 2018

1 reference

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Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

Characterization of mouse Ire1 alpha: cloning, mRNA localization in the brain and functional analysis in a neural cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

Differential requirements for caspase-8 activity in the mechanism of phosphorylation of eIF2alpha, cleavage of eIF4GI and signaling events associated with the inhibition of protein synthesis in apoptotic Jurkat T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

Calpain mediates eukaryotic initiation factor 4G degradation during global brain ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

Calpain activity in the rat brain after transient forebrain ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

A role for presenilin-1 in nuclear accumulation of Ire1 fragments and induction of the mammalian unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

ERp57 functions as a subunit of specific complexes formed with the ER lectins calreticulin and calnexin

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

Cell death, calcium mobilization, and immunostaining for phosphorylated eukaryotic initiation factor 2-alpha (eIF2alpha) in neuronally differentiated NB-104 cells: arachidonate and radical-mediated injury mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

Initiation of protein synthesis in eukaryotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

Global ischemia-induced inhibition of the coupling ratio of calcium uptake and ATP hydrolysis by rat whole brain microsomal Mg(2+)/Ca(2+) ATPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

Disturbances of calcium homeostasis within the endoplasmic reticulum may contribute to the development of ischemic-cell damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

Role of calcium in neuronal cell injury: which subcellular compartment is involved?

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

Activation of gadd153 expression through transient cerebral ischemia: evidence that ischemia causes endoplasmic reticulum dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

Erp72 expression activated by transient cerebral ischemia or disturbance of neuronal endoplasmic reticulum calcium stores

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

Intracellular signaling from the endoplasmic reticulum to the nucleus: the unfolded protein response in yeast and mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

p70 S6 kinase: an enigma with variations

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

Ischemia-induced inhibition of active calcium transport into gerbil brain microsomes: effect of anesthetics and models of ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

Stroke genomics: approaches to identify, validate, and understand ischemic stroke gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

Activity of protein phosphatases against initiation factor-2 and elongation factor-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

Development. The message is in the translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

The mammalian endoplasmic reticulum stress response element consists of an evolutionarily conserved tripartite structure and interacts with a novel stress-inducible complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

Translational control is required for the unfolded protein response and in vivo glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

Protein folding in the ER.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

Insulin induces dephosphorylation of eukaryotic initiation factor 2alpha and restores protein synthesis in vulnerable hippocampal neurons after transient brain ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

Persistent inhibition of protein synthesis precedes delayed neuronal death in postischemic gerbil hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

CHOP enhancement of gene transcription by interactions with Jun/Fos AP-1 complex proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

The heme-regulated eukaryotic initiation factor 2alpha kinase. A potential regulatory target for control of protein synthesis by diffusible gases

21 January 2018

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Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

21 January 2018

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Induction of glucose regulated protein (grp78) and inducible heat shock protein (hsp70) mRNAs in rat brain after kainic acid seizures and focal ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153).

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

Cloning of mammalian Ire1 reveals diversity in the ER stress responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

The unfolded protein response pathway in Saccharomyces cerevisiae. Oligomerization and trans-phosphorylation of Ire1p (Ern1p) are required for kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

Protein serine/threonine phosphatase Ptc2p negatively regulates the unfolded-protein response by dephosphorylating Ire1p kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

Brain ischemia and reperfusion: molecular mechanisms of neuronal injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

Regulation of transcription factor C/ATF by the cAMP signal activation in hippocampal neurons, and molecular interaction of C/ATF with signal integrator CBP/p300.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F00004647-200202000-00001

10.1097/00004647-200202000-00001

21 January 2018

Identifiers

DOI

1 reference

Dimensions Publication ID

2 August 2017

1032907082

0 references

1 reference