(Q34514386)

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Roles of the active site water, histidine 303, and phenylalanine 396 in the catalytic mechanism of the elongation condensing enzyme of Streptococcus pneumoniae

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 August 2017

Roles of the active site water, histidine 303, and phenylalanine 396 in the catalytic mechanism of the elongation condensing enzyme of Streptococcus pneumoniae (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Streptococcus pneumoniae

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author name string

Yong-Mei Zhang

1

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Jason Hurlbert

2

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Stephen W White

3

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Charles O Rock

4

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Europe PubMed Central

PubMed publication ID

2 August 2017

language of work or name

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publication date

16 April 2006

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Europe PubMed Central

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2 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

2 August 2017

281

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Europe PubMed Central

PubMed publication ID

2 August 2017

25

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

17390-17399

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Forty years of bacterial fatty acid synthesis

1 reference

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Structural and functional organization of the animal fatty acid synthase

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The Claisen condensation in biology

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Mechanism of the beta-ketoacyl synthase reaction catalyzed by the animal fatty acid synthase

1 reference

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Escherichia coli as a model for the regulation of dissociable (type II) fatty acid biosynthesis

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Lipid biosynthesis as a target for antibacterial agents

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Bacterial fatty acid biosynthesis: targets for antibacterial drug discovery

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Effect of the anorectic fatty acid synthase inhibitor C75 on neuronal activity in the hypothalamus and brainstem

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The Anorexigenic Fatty Acid Synthase Inhibitor, C75, Is a Nonspecific Neuronal Activator

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Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells

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Long-term effects of a fatty acid synthase inhibitor on obese mice: food intake, hypothalamic neuropeptides, and UCP3.

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Crystal structure of beta-ketoacyl-acyl carrier protein synthase II from E.coli reveals the molecular architecture of condensing enzymes

1 reference

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The crystal structure of beta-ketoacyl-acyl carrier protein synthase II from Synechocystis sp. at 1.54 A resolution and its relationship to other condensing enzymes

1 reference

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21 January 2018

The 1.3-Angstrom-resolution crystal structure of beta-ketoacyl-acyl carrier protein synthase II from Streptococcus pneumoniae

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Molecular cloning and sequencing of cDNAs encoding the entire rat fatty acid synthase

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The 1.8 A crystal structure and active-site architecture of beta-ketoacyl-acyl carrier protein synthase III (FabH) from escherichia coli

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Inhibition of beta-ketoacyl-acyl carrier protein synthases by thiolactomycin and cerulenin. Structure and mechanism

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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Regulation of fatty acid elongation and initiation by acyl-acyl carrier protein in Escherichia coli.

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21 January 2018

Rational pathway engineering of type I fatty acid synthase allows the biosynthesis of triacetic acid lactone from D-glucose in vivo

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21 January 2018

Overproduction of beta-ketoacyl-acyl carrier protein synthase I imparts thiolactomycin resistance to Escherichia coli K-12

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21 January 2018

Homogeneous assays for single-nucleotide polymorphism typing using AlphaScreen

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Refinement of macromolecular structures by the maximum-likelihood method

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21 January 2018

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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21 January 2018

Improved methods for building protein models in electron density maps and the location of errors in these models

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21 January 2018

beta-Ketoacyl-[acyl carrier protein] synthase I of Escherichia coli: aspects of the condensation mechanism revealed by analyses of mutations in the active site pocket

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21 January 2018

Structure of the complex between the antibiotic cerulenin and its target, beta-ketoacyl-acyl carrier protein synthase

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21 January 2018

High resolution crystal structures of human cytosolic thiolase (CT): a comparison of the active sites of human CT, bacterial thiolase, and bacterial KAS I.

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21 January 2018

The X-ray crystal structure of beta-ketoacyl [acyl carrier protein] synthase I

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21 January 2018

Fatty acid synthesis. Role of active site histidines and lysine in Cys-His-His-type beta-ketoacyl-acyl carrier protein synthases

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21 January 2018

The 1.8 A crystal structure of the dimeric peroxisomal 3-ketoacyl-CoA thiolase of Saccharomyces cerevisiae: implications for substrate binding and reaction mechanism

1 reference

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21 January 2018

Structures of beta-ketoacyl-acyl carrier protein synthase I complexed with fatty acids elucidate its catalytic machinery

1 reference

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21 January 2018

Crystal structure of beta-ketoacyl-acyl carrier protein synthase III. A key condensing enzyme in bacterial fatty acid biosynthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513199200

21 January 2018

Refined structures of beta-ketoacyl-acyl carrier protein synthase III

1 reference

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21 January 2018

Crystal structure of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III

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21 January 2018

Probing the mechanism of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III mtFabH: factors influencing catalysis and substrate specificity

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Preparative enzymatic synthesis of acyl-acyl carrier protein

1 reference

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Control of the synthesis of long-chain fatty acids and triacetic acid in E. coli

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M513199200

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

ResearchGate publication ID

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