(Q34436455)

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Probing the mechanism of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III mtFabH: factors influencing catalysis and substrate specificity

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Europe PubMed Central

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2 August 2017

Probing the mechanism of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III mtFabH: factors influencing catalysis and substrate specificity (English)

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Europe PubMed Central

PubMed publication ID

2 August 2017

Mycobacterium tuberculosis

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7

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2 August 2017

object named as

Lynn G Dover

5

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object named as

Laurent Kremer

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2 August 2017

author name string

Alistair K Brown

1

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Europe PubMed Central

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2 August 2017

Sudharsan Sridharan

2

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Europe PubMed Central

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2 August 2017

Sandra Lindenberg

4

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2 August 2017

James C Sacchettini

6

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2 August 2017

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publication date

22 July 2005

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2 August 2017

Journal of Biological Chemistry

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2 August 2017

280

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2 August 2017

37

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Europe PubMed Central

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2 August 2017

32539-32547

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Europe PubMed Central

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2 August 2017

Consensus statement. Global burden of tuberculosis: estimated incidence, prevalence, and mortality by country. WHO Global Surveillance and Monitoring Project

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Tuberculosis control: the relevance of classic principles in an era of acquired immunodeficiency syndrome and multidrug resistance

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Tuberculosis drug resistance: a global threat

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Molecular modeling and simulation of Mycobacterium tuberculosis cell wall permeability.

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https://api.crossref.org/works/10.1074%2FJBC.M413216200

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The Envelope of Mycobacteria

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21 January 2018

Comparative cell wall core biosynthesis in the mycolated pathogens, Mycobacterium tuberculosis and Corynebacterium diphtheriae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413216200

21 January 2018

Mycolic acid biosynthesis and enzymic characterization of the beta-ketoacyl-ACP synthase A-condensing enzyme from Mycobacterium tuberculosis

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21 January 2018

A polyketide synthase catalyzes the last condensation step of mycolic acid biosynthesis in mycobacteria and related organisms

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21 January 2018

Structural and functional organization of the animal fatty acid synthase

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21 January 2018

Product diversity and regulation of type II fatty acid synthases

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21 January 2018

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

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Inhibition of a Mycobacterium tuberculosis beta-ketoacyl ACP synthase by isoniazid.

1 reference

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21 January 2018

Thiolactomycin and related analogues as novel anti-mycobacterial agents targeting KasA and KasB condensing enzymes in Mycobacterium tuberculosis

1 reference

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21 January 2018

The Claisen condensation in biology

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21 January 2018

Purification and biochemical characterization of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthases KasA and KasB

1 reference

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21 January 2018

The 1.8 A crystal structure and active-site architecture of beta-ketoacyl-acyl carrier protein synthase III (FabH) from escherichia coli

1 reference

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21 January 2018

Crystal structure of beta-ketoacyl-acyl carrier protein synthase III. A key condensing enzyme in bacterial fatty acid biosynthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413216200

21 January 2018

Crystal structure of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413216200

21 January 2018

Over-production of proteins in Escherichia coli: mutant hosts that allow synthesis of some membrane proteins and globular proteins at high levels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413216200

21 January 2018

Biochemical characterization of acyl carrier protein (AcpM) and malonyl-CoA:AcpM transacylase (mtFabD), two major components of Mycobacterium tuberculosis fatty acid synthase II

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413216200

21 January 2018

Inhibition of beta-ketoacyl-acyl carrier protein synthase III (FabH) by acyl-acyl carrier protein in Escherichia coli.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413216200

21 January 2018

beta-Ketoacyl-[acyl carrier protein] synthase I of Escherichia coli: aspects of the condensation mechanism revealed by analyses of mutations in the active site pocket

1 reference

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21 January 2018

Processing of X-ray diffraction data collected in oscillation mode

1 reference

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SWISS-MODEL: An automated protein homology-modeling server

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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21 January 2018

Improved methods for building protein models in electron density maps and the location of errors in these models

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21 January 2018

An approach to multi-copy search in molecular replacement

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21 January 2018

The CCP4 suite: programs for protein crystallography

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21 January 2018

XtalView/Xfit--A versatile program for manipulating atomic coordinates and electron density

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21 January 2018

Effective electron-density map improvement and structure validation on a Linux multi-CPU web cluster: The TB Structural Genomics Consortium Bias Removal Web Service

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413216200

21 January 2018

The biosynthesis of mycolic acids in Mycobacterium tuberculosis. Enzymatic methyl(ene) transfer to acyl carrier protein bound meromycolic acid in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413216200

21 January 2018

Purification, characterization, and identification of novel inhibitors of the beta-ketoacyl-acyl carrier protein synthase III (FabH) from Staphylococcus aureus

1 reference

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21 January 2018

Development of a scintillation proximity assay for beta-ketoacyl-acyl carrier protein synthase III.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413216200

21 January 2018

Identification and analysis of the acyl carrier protein (ACP) docking site on beta-ketoacyl-ACP synthase III

1 reference

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21 January 2018

Crystal structure of a substrate complex of Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III (FabH) with lauroyl-coenzyme A

1 reference

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21 January 2018

The solution structure of acyl carrier protein from Mycobacterium tuberculosis

1 reference

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21 January 2018

Mechanism of chalcone synthase. pKa of the catalytic cysteine and the role of the conserved histidine in a plant polyketide synthase.

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A solution for the best rotation to relate two sets of vectors

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Impact of tuberculosis (TB) on HIV-1 activity in dually infected patients

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21 January 2018

Identifiers

10.1074/JBC.M413216200

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

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