(Q34514412)

2 August 2017

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title

Rat genetics: attaching physiology and pharmacology to the genome (English)

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2 August 2017

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Anne E Kwitek

2

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author name string

Howard J Jacob

series ordinal

1

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2 August 2017

publication date

1 January 2002

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2 August 2017

published in

Nature Reviews Genetics

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2 August 2017

volume

3

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2 August 2017

issue

1

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2 August 2017

page(s)

33-42

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The origin of common laboratory mice

2 August 2017

cites work

1 reference

The rat as an experimental animal

31 March 2020

1 reference

Genetic mapping of a gene causing hypertension in the stroke-prone spontaneously hypertensive rat

31 March 2020

1 reference

Resolution of quantitative traits into Mendelian factors by using a complete linkage map of restriction fragment length polymorphisms

31 March 2020

1 reference

Identification of susceptibility loci for insulin-dependent diabetes mellitus by trans-racial gene mapping.

31 March 2020

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Chromosomal mapping of two genetic loci associated with blood-pressure regulation in hereditary hypertensive rats

31 March 2020

1 reference

Genetic analysis of inherited hypertension in the rat.

31 March 2020

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Spontaneous diabetes mellitus syndrome in the rat. IV. Immunogenetic interactions of MHC and non-MHC components of the syndrome

31 March 2020

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Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 gene

31 March 2020

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Positional cloning of the mouse obese gene and its human homologue

31 March 2020

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Modulation of circulating leptin levels by its soluble receptor

31 March 2020

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Altering the genome by homologous recombination

31 March 2020

1 reference

Suggestive Evidence for Association of Human Chromosome 18q12-q21 and Its Orthologue on Rat and Mouse Chromosome 18 With Several Autoimmune Diseases

31 March 2020

1 reference

Hypertension: genes and environment

31 March 2020

1 reference

Complex interactions of new quantitative trait loci, Sluc1, Sluc2, Sluc3, and Sluc4, that influence the susceptibility to lung cancer in the mouse

31 March 2020

1 reference

The battle of two genomes: genetics of bacterial host/pathogen interactions in mice

31 March 2020

1 reference

Genomic screen for QTLs underlying alcohol consumption in the P and NP rat lines

31 March 2020

1 reference

The roads from phenotypic variation to gene discovery: mutagenesis versus QTLs

31 March 2020

1 reference

fw2.2: a quantitative trait locus key to the evolution of tomato fruit size

31 March 2020

1 reference

Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus

31 March 2020

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Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

31 March 2020

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A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

31 March 2020

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Finding the molecular basis of quantitative traits: successes and pitfalls.

31 March 2020

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Localization of two insulin-dependent diabetes (Idd) genes to the Idd10 region on mouse Chromosome 3

31 March 2020

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Transgenic rescue of defective Cd36 ameliorates insulin resistance in spontaneously hypertensive rats

31 March 2020

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Quantitative trait loci for cellular defects in glucose and fatty acid metabolism in hypertensive rats

31 March 2020

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Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats.

31 March 2020

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Functional screening of 2 Mb of human chromosome 21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome

31 March 2020

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Functional screening of an asthma QTL in YAC transgenic mice.

31 March 2020

1 reference

A new logic for DNA engineering using recombination in Escherichia coli

31 March 2020

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Rapid modification of bacterial artificial chromosomes by ET-recombination.

31 March 2020

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Quantitative trait loci in Drosophila

31 March 2020

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Nuclear transfer of adult and genetically modified fetal cells of the rat.

31 March 2020

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Capitalizing on large-scale mouse mutagenesis screens

31 March 2020

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A pharmacogenetic approach to blood pressure in Lyon hypertensive rats. A chromosome 2 locus influences the response to a calcium antagonist

31 March 2020

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The deletion/insertion polymorphism of the angiotensin converting enzyme gene and cardiovascular-renal risk

31 March 2020

1 reference

Genetic susceptibility for human familial essential hypertension in a region of homology with blood pressure linkage on rat chromosome 10.

31 March 2020

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Multilocus linkage of familial hyperkalaemia and hypertension, pseudohypoaldosteronism type II, to chromosomes 1q31-42 and 17p11-q21

31 March 2020

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Human hypertension caused by mutations in WNK kinases

31 March 2020

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New target regions for human hypertension via comparative genomics

31 March 2020

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Genetic Analysis of Blood Pressure in Spontaneously Hypertensive Rats

31 March 2020

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Concordance of murine quantitative trait loci for salt-induced hypertension with rat and human loci

31 March 2020

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The human obesity gene map: the 2000 update

31 March 2020

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Clustering of non-major histocompatibility complex susceptibility candidate loci in human autoimmune diseases

31 March 2020

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Mapping autoimmunity genes

31 March 2020

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Automated construction of high-density comparative maps between rat, human, and mouse

31 March 2020

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High-resolution mapping of quantitative trait loci in outbred mice

31 March 2020

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Natural selection mapping of the warfarin-resistance gene

31 March 2020

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Linkage disequilibrium and haplotype mapping of a skin cancer susceptibility locus in outbred mice

31 March 2020

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In silico mapping of complex disease-related traits in mice.

31 March 2020

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Linkage disequilibrium in the human genome

31 March 2020

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The recombinant congenic strains for analysis of multigenic traits: genetic composition

31 March 2020

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Genetic composition of the recombinant congenic strains

31 March 2020

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Analysing complex genetic traits with chromosome substitution strains

31 March 2020

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The promise of comparative genomics in mammals

31 March 2020

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A genomic-systems biology map for cardiovascular function

31 March 2020

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Preimplantation and postimplantation development of rat embryos cloned with cumulus cells and fibroblasts.

31 March 2020

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRG702

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Dimensions Publication ID

2 August 2017

1045686222

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