(Q34514721)

PubMed publication ID

11306611

2 August 2017

title

Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762519&resulttype=core&format=json

12 May 2020

0 references

1 reference

1 reference

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T Tikka

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762519&resulttype=core&format=json

12 May 2020

B L Fiebich

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762519&resulttype=core&format=json

12 May 2020

G Goldsteins

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762519&resulttype=core&format=json

12 May 2020

R Keinanen

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762519&resulttype=core&format=json

12 May 2020

J Koistinaho

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762519&resulttype=core&format=json

12 May 2020

language of work or name

English

0 references

publication date

1 April 2001

1 reference

PubMed publication ID

11306611

2 August 2017

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762519&resulttype=core&format=json

12 May 2020

volume

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762519&resulttype=core&format=json

12 May 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762519&resulttype=core&format=json

12 May 2020

page(s)

2580-2588

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762519&resulttype=core&format=json

describes a project that uses

12 May 2020

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6762519/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Pathobiology of ischaemic stroke: an integrated view

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Autoimmune encephalomyelitis ameliorated by AMPA antagonists

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Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice

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Interleukin-1beta induces cyclooxygenase-2 and prostaglandin E(2) synthesis in human neuroblastoma cells: involvement of p38 mitogen-activated protein kinase and nuclear factor-kappaB.

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Cytokines and their receptors in the central nervous system: physiology, pharmacology, and pathology

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Excitotoxic brain damage in the rat induces interleukin-1beta protein in microglia and astrocytes: correlation with the progression of cell death

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Excitotoxicity, free radicals, and cell membrane changes

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Aging, energy, and oxidative stress in neurodegenerative diseases.

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Role of astrocytes in glutamate homeostasis. Implications for excitotoxicity

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12 December 2020

A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window

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12 December 2020

Expression of ionotropic glutamate receptor subunits in glial cells of the hippocampal CA1 area following transient forebrain ischemia

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12 December 2020

Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease

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Microglia: a sensor for pathological events in the CNS

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Potentiation of N-methyl-D-aspartate-mediated neurotoxicity by immunostimulated murine microglia

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Glutamate receptor signaling interplay modulates stress-sensitive mitogen-activated protein kinases and neuronal cell death

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Tetracyclines inhibit connective tissue breakdown by multiple non-antimicrobial mechanisms

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p38 MAP kinase activation by Clostridium difficile toxin A mediates monocyte necrosis, IL-8 production, and enteritis

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p38 but not p44/42 mitogen-activated protein kinase is required for nitric oxide synthase induction mediated by lipopolysaccharide in RAW 264.7 macrophages

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Activation of mitogen-activated protein kinases after transient forebrain ischemia in gerbil hippocampus

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Cerebral ischemia and seizures induce tyrosine phosphorylation of PYK2 in neurons and microglial cells

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Reactive microgliosis

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Excitotoxic cell death

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Relation Between Lipophilicity and Pharmacological Behavior of Minocycline, Doxycycline, Tetracycline, and Oxytetracycline in Dogs

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A novel mechanism of action of chemically modified tetracyclines: inhibition of COX-2-mediated prostaglandin E2 production

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Eicosanoids and nitric oxide influence induction of reactive gliosis from spreading depression in microglia but not astrocytes

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Inflammatory glia mediate delayed neuronal damage after ischemia in the central nervous system

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Microglial tissue plasminogen activator (tPA) triggers neuronal apoptosis in vitro

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Neurotoxic responses by microglia elicited by excitotoxic injury in the mouse hippocampus

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12 December 2020

The changing landscape of ischaemic brain injury mechanisms.

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12 December 2020

Glutamatergic receptors regulate expression, phosphorylation and accumulation of neurofilaments in spinal cord neurons

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MEK1 protein kinase inhibition protects against damage resulting from focal cerebral ischemia

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12 December 2020

AMPA-kainate subtypes of glutamate receptor in rat cerebral microglia

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12 December 2020

Suppression of human neutrophil functions by tetracyclines

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12 December 2020

The Microglial Reaction in the Rat Dorsal Hippocampus following Transient Forebrain Ischemia

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12 December 2020

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12 December 2020

Inhibition of the p44/42 MAP kinase pathway protects hippocampal neurons in a cell-culture model of seizure activity

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A novel mechanism of action of tetracyclines: effects on nitric oxide synthases

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12 December 2020

Extracellular signal-regulated kinase and p38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor-alpha gene expression in endotoxin-stimulated primary glial cultures

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12 December 2020

Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia

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12 December 2020

Activation of p38MAPK in microglia after ischemia.

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12 December 2020

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1 reference

12 December 2020

Inflammatory mediators and stroke: new opportunities for novel therapeutics

1 reference

12 December 2020

10.1523/JNEUROSCI.21-08-02580.2001

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762519&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762519&resulttype=core&format=json

12 May 2020

PubMed publication ID

11306611

1 reference