(Q34519891)

2 August 2017

title

Geranylgeranyltransferase type I (GGTase-I) deficiency hyperactivates macrophages and induces erosive arthritis in mice (English)

1 reference

2 August 2017

Mohamed X Ibrahim

2

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Sofia Andersson

object named as

Sofia Andersson

9

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Claes Ohlsson

object named as

Claes Ohlsson

10

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Omar Khan

object named as

Omar M Khan

1

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author name string

Ing-Marie Jonsson

3

1 reference

2 August 2017

Christin Karlsson

4

1 reference

2 August 2017

Meng Liu

5

1 reference

2 August 2017

Anna-Karin M Sjogren

6

1 reference

2 August 2017

Frida J Olofsson

7

1 reference

2 August 2017

Mikael Brisslert

8

1 reference

2 August 2017

Lillemor Mattsson Hultén

11

1 reference

2 August 2017

Maria Bokarewa

12

1 reference

2 August 2017

Martin O Bergo

13

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2 August 2017

language of work or name

English

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publication date

25 January 2011

1 reference

Journal of Clinical Investigation

2 August 2017

published in

1 reference

2 August 2017

volume

121

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2 August 2017

issue

2

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2 August 2017

page(s)

628-639

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Regulation of Rho GTPase crosstalk, degradation and activity by RhoGDI1

2 August 2017

cites work

1 reference

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Targeting the protein prenyltransferases efficiently reduces tumor development in mice with K-RAS-induced lung cancer

7 July 2018

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Smoking and nicotine exposure delay development of collagen-induced arthritis in mice

7 July 2018

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Cell signalling in macrophages, the principal innate immune effector cells of rheumatoid arthritis

7 July 2018

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7 July 2018

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HMG-CoA reductase inhibition induces IL-1beta release through Rac1/PI3K/PKB-dependent caspase-1 activation

7 July 2018

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Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division

7 July 2018

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Statin treatment for rheumatoid arthritis: a promising novel indication

7 July 2018

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The central role of T cells in rheumatoid arthritis

7 July 2018

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Effects of lovastatin on Rho isoform expression, activity, and association with guanine nucleotide dissociation inhibitors

7 July 2018

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GGTase-I deficiency reduces tumor formation and improves survival in mice with K-RAS-induced lung cancer

7 July 2018

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Inhibition of protein geranylgeranylation induces apoptosis in synovial fibroblasts

7 July 2018

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Changes in activation states of murine polymorphonuclear leukocytes (PMN) during inflammation: a comparison of bone marrow and peritoneal exudate PMN.

7 July 2018

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Statin therapy and autoimmune disease: from protein prenylation to immunomodulation

7 July 2018

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Thematic review series: lipid posttranslational modifications. geranylgeranylation of Rab GTPases.

7 July 2018

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Anti-inflammatory effects of statins: clinical evidence and basic mechanisms

7 July 2018

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Yersinia pseudotuberculosis spatially controls activation and misregulation of host cell Rac1.

7 July 2018

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Phosphorylation of serine 188 protects RhoA from ubiquitin/proteasome-mediated degradation in vascular smooth muscle cells

7 July 2018

1 reference

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Trial of Atorvastatin in Rheumatoid Arthritis (TARA): double-blind, randomised placebo-controlled trial

7 July 2018

1 reference

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T-cell regulation in rheumatoid arthritis

7 July 2018

1 reference

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Inactivation of Icmt inhibits transformation by oncogenic K-Ras and B-Raf

7 July 2018

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Activity of Rho-family GTPases during cell division as visualized with FRET-based probes

7 July 2018

1 reference

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7 July 2018

RHO-GTPases and cancer

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RhoA biological activity is dependent on prenylation but independent of specific isoprenoid modification.

7 July 2018

1 reference

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Interactions between Rho GTPases and Rho GDP dissociation inhibitor (Rho-GDI)

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026725

Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding

7 July 2018

1 reference

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Identification and characterization of the new osteoclast progenitor with macrophage phenotypes being able to differentiate into mature osteoclasts

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026725

Rho guanine dissociation inhibitors: pivotal molecules in cellular signalling

7 July 2018

1 reference

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Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation

7 July 2018

1 reference

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The mechanisms of action of disease-modifying antirheumatic drugs: a review with emphasis on macrophage signal transduction and the induction of proinflammatory cytokines

7 July 2018

1 reference

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Influence of metal ions on substrate binding and catalytic activity of mammalian protein geranylgeranyltransferase type-I

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026725

Consequences of weak interaction of rho GDI with the GTP-bound forms of rho p21 and rac p21.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026725

Isolation of protein prenyltransferases from bovine brain and baculovirus expression system

7 July 2018

1 reference

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Calcineurin activation protects T cells from glucocorticoid-induced apoptosis.

7 July 2018

1 reference

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Cachectin: more than a tumor necrosis factor

7 July 2018

1 reference

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Effect of irradiation, cyclophosphamide, and etoposide (VP-16) on number of peripheral blood and peritoneal leukocytes in mice under normal conditions and during acute inflammatory reaction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026725

Post-translational modifications of the C-terminal region of the rho protein are important for its interaction with membranes and the stimulatory and inhibitory GDP/GTP exchange proteins.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026725

Nf1 deficiency cooperates with oncogenic K-RAS to induce acute myeloid leukemia in mice.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026725

The impact of substance P signalling on the development of experimental staphylococcal sepsis and arthritis

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026725

Apoptosis of rheumatoid synovial cells by statins through the blocking of protein geranylgeranylation: a potential therapeutic approach to rheumatoid arthritis

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026725

Uric acid, a nucleic acid degradation product, down-regulates dsRNA-triggered arthritis

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026725

Genistein as an anti-inflammatory agent

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026725

Antiinflammatory effect of simvastatin in patients with rheumatoid arthritis

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026725

Role of prenylation in the interaction of Rho-family small GTPases with GTPase activating proteins.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026725

G proteins and small GTPases: distant relatives keep in touch

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026725

Harmful singlet oxygen can be helpful

27 October 2018

1 reference

12 December 2020

Role of macrophages in Staphylococcus aureus-induced arthritis and sepsis

1 reference

12 December 2020

Analysis of the synovial cell infiltrate in early rheumatoid synovial tissue in relation to local disease activity

1 reference

12 December 2020

Resistin, an adipokine with potent proinflammatory properties

1 reference

12 December 2020

Post-prenylation-processing enzymes as new targets in oncogenesis

1 reference

12 December 2020

A role for geranylgeranylation in interleukin-1beta secretion

1 reference

12 December 2020

Simvastatin stimulates macrophage interleukin-1β secretion through an isoprenylation-dependent mechanism

1 reference

12 December 2020

Soluble receptor for advanced glycation end products triggers a proinflammatory cytokine cascade via beta2 integrin Mac-1

1 reference

12 December 2020

mgrA regulates staphylococcal virulence important for induction and progression of septic arthritis and sepsis

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI43758

1 reference

2 August 2017

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2 August 2017

1 reference