(Q34520118)

2 August 2017

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title

Caspase-dependent apoptotic pathways in CNS injury (English)

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2 August 2017

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Yakovlev AG

1

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PubMed ID

11831549

2 August 2017

Faden AI

series ordinal

2

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2 August 2017

1 August 2001

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2 August 2017

Molecular Neurobiology

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2 August 2017

24

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2 August 2017

131-144

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2 August 2017

1-3

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https://scigraph.springernature.com/pub.10.1385/mn:24:1-3:131

2 August 2017

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cites work

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

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12 December 2020

Prolonged therapeutic window for ischemic brain damage caused by delayed caspase activation.

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12 December 2020

Programmed cell death in Caenorhabditis elegans

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12 December 2020

Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

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12 December 2020

Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis

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12 December 2020

Neuronal apoptosis induced by beta-amyloid is mediated by caspase-8.

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12 December 2020

Caspases and neurodegeneration: on the cutting edge of new therapeutic approaches.

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12 December 2020

Expression and functional analysis of Apaf-1 isoforms. Extra Wd-40 repeat is required for cytochrome c binding and regulated activation of procaspase-9

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12 December 2020

Caspase-8 and caspase-3 are expressed by different populations of cortical neurons undergoing delayed cell death after focal stroke in the rat.

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12 December 2020

The domains of death: evolution of the apoptosis machinery

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12 December 2020

Cell death: the significance of apoptosis

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12 December 2020

Inhibition of death receptor signals by cellular FLIP

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12 December 2020

Caspase-3 mediated neuronal death after traumatic brain injury in rats

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12 December 2020

Protease activation during apoptosis: death by a thousand cuts?

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12 December 2020

Acceleration of apoptotic cell death after the cleavage of Bcl-XL protein by caspase-3-like proteases

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12 December 2020

Release of mitochondrial cytochrome c and DNA fragmentation after cold injury-induced brain trauma in mice: possible role in neuronal apoptosis.

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12 December 2020

Caspase inhibition selectively reduces the apoptotic component of oxygen-glucose deprivation-induced cortical neuronal cell death

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12 December 2020

In vivo evidence that caspase-3 is required for Fas-mediated apoptosis of hepatocytes

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12 December 2020

A pathway of neuronal apoptosis induced by hypoxia/reoxygenation: roles of nuclear factor-kappaB and Bcl-2

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12 December 2020

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

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12 December 2020

Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia

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12 December 2020

Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD

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12 December 2020

Apoptosis. Death by crowd control

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12 December 2020

Apaf1 is required for mitochondrial pathways of apoptosis and brain development

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12 December 2020

Bax membrane insertion during Fas(CD95)-induced apoptosis precedes cytochrome c release and is inhibited by Bcl-2.

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12 December 2020

Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome

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12 December 2020

Bax-induced cytochrome C release from mitochondria is independent of the permeability transition pore but highly dependent on Mg2+ ions

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12 December 2020

Movement of Bax from the cytosol to mitochondria during apoptosis

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12 December 2020

Apoptosis and neurologic disease

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12 December 2020

Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3

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12 December 2020

BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial changes and cell death

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12 December 2020

Regulated targeting of BAX to mitochondria.

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12 December 2020

Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis

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12 December 2020

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

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12 December 2020

Phosphorylation-dependent Akt cleavage in neural cell in vitro reconstitution of apoptosis

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12 December 2020

Intracerebral injection of caspase-3 inhibitor prevents neuronal apoptosis after kainic acid-evoked status epilepticus

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12 December 2020

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

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12 December 2020

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

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12 December 2020

Caspases: enemies within

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12 December 2020

CPP32/CASPASE-3-like proteases in hypoxia-induced apoptosis in developing brain neurons.

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12 December 2020

Differential requirement for caspase 9 in apoptotic pathways in vivo.

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12 December 2020

Programmed cell death in the nematode C. elegans.

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12 December 2020

Caspase-8 is required for cell death induced by expanded polyglutamine repeats.

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12 December 2020

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

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12 December 2020

Cytochrome c release and caspase activation in traumatic axonal injury

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12 December 2020

Is neuronal injury caused by hypoglycemic coma of the necrotic or apoptotic type?

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12 December 2020

Molecular mechanisms of UV-induced apoptosis

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12 December 2020

Protein phosphatase 1alpha is a Ras-activated Bad phosphatase that regulates interleukin-2 deprivation-induced apoptosis

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12 December 2020

Apoptosis by death factor

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12 December 2020

Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE.

1 reference

12 December 2020

Two CD95 (APO-1/Fas) signaling pathways

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12 December 2020

Fas/CD95/APO-1 can function as a death receptor for neuronal cells in vitro and in vivo and is upregulated following cerebral hypoxic-ischemic injury to the developing rat brain

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12 December 2020

Multiple Bcl-2 family members demonstrate selective dimerizations with Bax

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12 December 2020

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

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12 December 2020

Identification of an endogenous dominant-negative short isoform of caspase-9 that can regulate apoptosis

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12 December 2020

Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90

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12 December 2020

Akt phosphorylation site found in human caspase-9 is absent in mouse caspase-9.

1 reference

12 December 2020

A novel Bcl-x isoform connected to the T cell receptor regulates apoptosis in T cells

1 reference

12 December 2020

Neuronal death in amyotrophic lateral sclerosis is apoptosis: possible contribution of a programmed cell death mechanism

1 reference

12 December 2020

Neural injury, repair and adaptation in the GI tract. I. New insights into neuronal injury: a cautionary tale.

1 reference

12 December 2020

Nitric oxide, cytochrome c and mitochondria

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12 December 2020

Postnatal distribution of cpp32/caspase 3 mRNA in the mouse central nervous system: an in situ hybridization study.

1 reference

12 December 2020

Apoptosis and necrosis in cerebrovascular disease

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12 December 2020

bcl-XL is the major bcl-x mRNA form expressed during murine development and its product localizes to mitochondria

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12 December 2020

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

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12 December 2020

Cathepsin B-mediated activation of the proinflammatory caspase-11.

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12 December 2020

Human ICE/CED-3 protease nomenclature

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12 December 2020

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

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12 December 2020

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

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12 December 2020

Genetic control of programmed cell death in the nematode Caenorhabditis elegans.

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12 December 2020

Regulation of cell death protease caspase-9 by phosphorylation

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12 December 2020

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

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12 December 2020

Molecular mechanisms of apoptosis induced by cytotoxic chemicals

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12 December 2020

An endoplasmic reticulum-specific stress-activated caspase (caspase-12) is implicated in the apoptosis of A549 epithelial cells by respiratory syncytial virus

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12 December 2020

The apoptosome: heart and soul of the cell death machine

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12 December 2020

In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains

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12 December 2020

Alternative splicing and programmed cell death

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12 December 2020

Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor

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12 December 2020

Cell death mechanisms in Parkinson's disease

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12 December 2020

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

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12 December 2020

An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

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12 December 2020

The role of CED-3-related cysteine proteases in apoptosis of cerebellar granule cells.

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12 December 2020

Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions

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12 December 2020

Bcl-x(S) anatagonizes the protective effects of Bcl-x(L).

1 reference

12 December 2020

The Caenorhabditis elegans cell death gene ced-4 encodes a novel protein and is expressed during the period of extensive programmed cell death

1 reference

12 December 2020

Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

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12 December 2020

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

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12 December 2020

Fas receptor and neuronal cell death after spinal cord ischemia

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12 December 2020

In situ immunodetection of neuronal caspase-3 activation in Alzheimer disease.

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12 December 2020

The Destabilization of Lipid Membranes Induced by the C-terminal Fragment of Caspase 8-cleaved Bid Is Inhibited by the N-terminal Fragment

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12 December 2020

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

1 reference

12 December 2020

Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia.

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12 December 2020

Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development

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12 December 2020

Activation of the caspase-3 apoptotic cascade in traumatic spinal cord injury

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12 December 2020

Activation of CPP-32 protease in hippocampal neurons following ischemia and epilepsy.

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12 December 2020

Implication of cysteine proteases calpain, cathepsin and caspase in ischemic neuronal death of primates

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12 December 2020

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

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12 December 2020

Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

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12 December 2020

Adult Apaf-1-deficient mice exhibit male infertility

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12 December 2020

N-Methyl-D-aspartate antagonists and apoptotic cell death triggered by head trauma in developing rat brain

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12 December 2020

Bax deficiency prevents the increased cell death of immature neurons in bcl-x-deficient mice

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12 December 2020

Pharmacological treatment of central nervous system trauma

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12 December 2020

Increases in Bcl-2 and cleavage of caspase-1 and caspase-3 in human brain after head injury.

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12 December 2020

Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models.

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12 December 2020

Involvement of caspase-3 in cell death after hypoxia-ischemia declines during brain maturation

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12 December 2020

Investigation of bax-induced release of cytochrome c from yeast mitochondria permeability of mitochondrial membranes, role of VDAC and ATP requirement

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12 December 2020

Caspase inhibition extends the commitment to neuronal death beyond cytochrome c release to the point of mitochondrial depolarization

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12 December 2020

Ischemic cell death in brain neurons

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12 December 2020

Pro-apoptotic apoptosis protease-activating factor 1 (Apaf-1) has a cytoplasmic localization distinct from Bcl-2 or Bcl-x(L).

1 reference

12 December 2020

BAX is required for neuronal death after trophic factor deprivation and during development

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12 December 2020

Attenuation of delayed neuronal death after mild focal ischemia in mice by inhibition of the caspase family.

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12 December 2020

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12 December 2020

Apoptotic neurodegeneration following trauma is markedly enhanced in the immature brain.

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12 December 2020

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

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12 December 2020

Studies of cellular injury in isolated flounder tubules. I. Correlation between morphology and function of control tubules and observations of autophagocytosis and mechanical cell damage

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12 December 2020

Combined mechanical trauma and metabolic impairment in vitro induces NMDA receptor-dependent neuronal cell death and caspase-3-dependent apoptosis.

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12 December 2020

Akt regulates cell survival and apoptosis at a postmitochondrial level

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12 December 2020

Long-term effect of inhibition of ced 3-like caspases on the survival of axotomized retinal ganglion cells in vivo

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12 December 2020

Caspase-3: A vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease.

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12 December 2020

Bcl-2 family members do not inhibit apoptosis by binding the caspase activator Apaf-1

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12 December 2020

Caspase-9, Bcl-XL, and Apaf-1 form a ternary complex

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12 December 2020

Understanding IAP function and regulation: a view from Drosophila

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12 December 2020

Ceramide induces cytochrome c release from isolated mitochondria

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12 December 2020

Proteases in apoptosis

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12 December 2020

CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme

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12 December 2020

Hsp27 negatively regulates cell death by interacting with cytochrome c.

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12 December 2020

Death receptors: signaling and modulation

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12 December 2020

Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury.

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12 December 2020

Caspases: the executioners of apoptosis

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12 December 2020

Identifiers

DOI

10.1385/MN:24:1-3:131

1 reference

PubMed ID

11831549

Dimensions Publication ID

2 August 2017

0 references

1 reference

PubMed ID

11831549