(Q34520437)

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Delayed Onset and Reduced Cognitive Deficits through Pre-Conditioning with 3-Nitropropionic Acid is Dependent on Sex and CAG Repeat Length in the R6/2 Mouse Model of Huntington's Disease

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 August 2017

Delayed Onset and Reduced Cognitive Deficits through Pre-Conditioning with 3-Nitropropionic Acid is Dependent on Sex and CAG Repeat Length in the R6/2 Mouse Model of Huntington's Disease (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Huntington's disease

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2

object named as

A Jennifer Morton

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

author name string

Elizabeth A Skillings

1

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

publication date

1 March 2016

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Journal of Huntington's Disease

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Europe PubMed Central

PubMed publication ID

2 August 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

19-32

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Serial changes of cerebral glucose metabolism and caudate size in persons at risk for Huntington's disease.

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Striatal glucose consumption in chorea-free subjects at risk of Huntington's disease

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Evidence for impairment of energy metabolism in vivo in Huntington's disease using localized 1H NMR spectroscopy

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Oxidative damage and metabolic dysfunction in Huntington's disease: selective vulnerability of the basal ganglia.

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

The use of the R6 transgenic mouse models of Huntington's disease in attempts to develop novel therapeutic strategies

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Increased metabolism in the R6/2 mouse model of Huntington's disease.

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Paradoxical delay in the onset of disease caused by super-long CAG repeat expansions in R6/2 mice.

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

1H NMR spectroscopy studies of Huntington's disease: correlations with CAG repeat numbers

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Lesion of striatal neurons with kainic acid provides a model for Huntington's chorea

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Duplication of biochemical changes of Huntington's chorea by intrastriatal injections of glutamic and kainic acids

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Excitotoxic injury of the neostriatum: a model for Huntington's disease

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Oxidative stress, glutamate, and neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Targeting glutamate mediated excitotoxicity in Huntington's disease: neural progenitors and partial glutamate antagonist--memantine

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Neurotoxicity of glutamate uptake inhibition in vivo: correlation with succinate dehydrogenase activity and prevention by energy substrates

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Exacerbation of excitotoxic neuronal death induced during mitochondrial inhibition in vivo: relation to energy imbalance or ATP depletion?

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Mice transgenic for the human Huntington's disease mutation have reduced sensitivity to kainic acid toxicity

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Distribution of phosphate-activated glutaminase, succinic dehydrogenase, pyruvate dehydrogenase and gamma-glutamyl transpeptidase in post-mortem brain from Huntington's disease and agonal cases

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

A large number of protein expression changes occur early in life and precede phenotype onset in a mouse model for huntington disease

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

3-Nitropropionate, the toxic substance of Indigofera , is a suicide inactivator of succinate dehydrogenase

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Age-dependent vulnerability of the striatum to the mitochondrial toxin 3-nitropropionic acid.

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Chronic mitochondrial energy impairment produces selective striatal degeneration and abnormal choreiform movements in primates

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Replicating Huntington's disease phenotype in experimental animals

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

3-Nitropropionic acid animal model and Huntington's disease

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Mice transgenic for the Huntington's disease mutation are resistant to chronic 3-nitropropionic acid-induced striatal toxicity.

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Preconditioning: evolution of basic mechanisms to potential therapeutic strategies

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Increase of hypoxic tolerance in rat hippocampal slices following 3-nitropropionic acid is not mediated by endogenous nerve growth factor.

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Chemical preconditioning: a cytoprotective strategy

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Chemical preconditioning with 3-nitropropionic acid: lack of induction of neuronal tolerance in gerbil hippocampus subjected to transient forebrain ischemia

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

The role of peroxynitrite in chemical preconditioning with 3-nitropropionic acid in rat hearts.

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Chemical preconditioning effect of 3-nitropropionic acid in anesthetized rat heart

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Ischaemic preconditioning in a model of global ischaemia: infarct size limitation, but no reduction of stunning

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Transgenic mice expressing a Huntington's disease mutation are resistant to quinolinic acid-induced striatal excitotoxicity

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Environmental stimulation increases survival in mice transgenic for exon 1 of the Huntington's disease gene

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Complexin II is essential for normal neurological function in mice.

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Measuring cognitive deficits in disabled mice using an automated interactive touchscreen system

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Atypical diabetes associated with inclusion formation in the R6/2 mouse model of Huntington's disease is not improved by treatment with hypoglycaemic agents.

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Involvement of mitochondrial complex II defects in neuronal death produced by N-terminus fragment of mutated huntingtin

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Cardiac dysfunction in the R6/2 mouse model of Huntington's disease

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Mitochondrial toxin 3-nitropropionic acid induces cardiac and neurotoxicity differentially in mice

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Chemical preconditioning by 3-nitropropionic acid reduces ischemia-reperfusion injury in rat heart

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

The mechanism of the late preconditioning effect of 3-nitropropionic acid.

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Responses to environmental enrichment differ with sex and genotype in a transgenic mouse model of Huntington's disease

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

"Brain training" improves cognitive performance and survival in a transgenic mouse model of Huntington's disease

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Estrogen protects against while testosterone exacerbates vulnerability of the lateral striatal artery to chemical hypoxia by 3-nitropropionic acid

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Estrogen blocks 3-nitropropionic acid-induced Ca2+i increase and cell damage in cultured rat cerebral endothelial cells

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Reduction of GnRH and infertility in the R6/2 mouse model of Huntington's disease

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Chronology of behavioral symptoms and neuropathological sequela in R6/2 Huntington's disease transgenic mice

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Excitotoxicity in Huntington disease

1 reference

https://api.crossref.org/works/10.3233%2FJHD-160189

21 January 2018

Identifiers

10.3233/JHD-160189

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

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