(Q34520533)

2 August 2017

Genetic circuit design automation (English)

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2 August 2017

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Alec A K Nielsen

1

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2 August 2017

Bryan S Der

2

1 reference

2 August 2017

Jonghyeon Shin

3

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2 August 2017

Prashant Vaidyanathan

4

1 reference

2 August 2017

Vanya Paralanov

5

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2 August 2017

Elizabeth A Strychalski

6

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2 August 2017

David Ross

7

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2 August 2017

Douglas Densmore

8

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2 August 2017

Christopher A Voigt

9

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2 August 2017

language of work or name

English

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publication date

1 April 2016

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2 August 2017

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2 August 2017

352

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2 August 2017

6281

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2 August 2017

aac7341

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Engineered gene circuits.

2 August 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Reconstruction of genetic circuits

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Designing biological systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Creation of a bacterial cell controlled by a chemically synthesized genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Synthetic biology moving into the clinic

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Parts plus pipes: synthetic biology approaches to metabolic engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Engineering static and dynamic control of synthetic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Simulation of prokaryotic genetic circuits

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Circuit simulation of genetic networks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

On schemes of combinatorial transcription logic

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

A synthetic oscillatory network of transcriptional regulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

A fast, robust and tunable synthetic gene oscillator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

A synthetic multicellular system for programmed pattern formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Designing customized cell signalling circuits

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Genetic programs constructed from layered logic gates in single cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Robust multicellular computing using genetically encoded NOR gates and chemical 'wires'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Development and characterization of AND-gate dynamic controllers with a modular synthetic GAL1 core promoter in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Amplifying genetic logic gates

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Rewritable digital data storage in live cells via engineered control of recombination directionality

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Permanent genetic memory with >1-byte capacity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Hysteresis in a synthetic mammalian gene network

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Synthetic analog computation in living cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

A synchronized quorum of genetic clocks

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Spatiotemporal control of gene expression with pulse-generating networks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

A tunable synthetic mammalian oscillator

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Diversity-based, model-guided construction of synthetic gene networks with predicted functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Design of a dynamic sensor-regulator system for production of chemicals and fuels derived from fatty acids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Five hard truths for synthetic biology

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

The second wave of synthetic biology: from modules to systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Directed evolution of a genetic circuit

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Composability of regulatory sequences controlling transcription and translation in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Causes and effects of N-terminal codon bias in bacterial genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Ribozyme-based insulator parts buffer synthetic circuits from genetic context

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Precise and reliable gene expression via standard transcription and translation initiation elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Genetic circuit performance under conditions relevant for industrial bioreactors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

A computational method for automated characterization of genetic components

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Effects of genetic variation on the E. coli host-circuit interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Gene regulation at the single-cell level

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Construction of a genetic toggle switch in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Long-term monitoring of bacteria undergoing programmed population control in a microchemostat

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Fast, cheap and somewhat in control

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

TinkerCell: modular CAD tool for synthetic biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

iBioSim: a tool for the analysis and design of genetic circuits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Automatic compilation from high-level biologically-oriented programming language to genetic regulatory networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

21 January 2018

Writing DNA with GenoCAD

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Automatic design of digital synthetic gene circuits

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Next generation simulation tools: the Systems Biology Workbench and BioSPICE integration

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Computational modeling of synthetic microbial biofilms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Measuring the activity of BioBrick promoters using an in vivo reference standard

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

A 'resource allocator' for transcription based on a highly fragmented T7 RNA polymerase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Genome-scale promoter engineering by coselection MAGE

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Refinement and standardization of synthetic biological parts and devices

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Toehold switches: de-novo-designed regulators of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Rationally designed families of orthogonal RNA regulators of translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Sequestration-based bistability enables tuning of the switching boundaries and design of a latch

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Multi-input CRISPR/Cas genetic circuits that interface host regulatory networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Orthogonal Cas9 proteins for RNA-guided gene regulation and editing

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Design and construction of a double inversion recombination switch for heritable sequential genetic memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

The Synthetic Biology Open Language (SBOL) provides a community standard for communicating designs in synthetic biology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Directed acyclic graph-based technology mapping of genetic circuit models

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Automated selection of synthetic biology parts for genetic regulatory networks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

AutoBioCAD: full biodesign automation of genetic circuits

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Optimal part and module selection for synthetic gene circuit design automation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Functional optimization of gene clusters by combinatorial design and assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Automated design of synthetic ribosome binding sites to control protein expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Visualization of evolutionary stability dynamics and competitive fitness of Escherichia coli engineered with randomized multigene circuits

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Characterization of 582 natural and synthetic terminators and quantification of their design constraints

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Predicting the strength of UP-elements and full-length E. coli σE promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Large-scale de novo DNA synthesis: technologies and applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

De novo protein design: fully automated sequence selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Computational design of receptor and sensor proteins with novel functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Computational design of ligand-binding proteins with high affinity and selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Engineering robust control of two-component system phosphotransfer using modular scaffolds

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Thermodynamics-based metabolic flux analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

A genome-scale metabolic reconstruction for Escherichia coli K-12 MG1655 that accounts for 1260 ORFs and thermodynamic information

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Specification and simulation of synthetic multicelled behaviors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

Extinction, coexistence, and localized patterns of a bacterial population with contact-dependent inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

SBOL Visual: A Graphical Language for Genetic Designs

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAC7341

21 January 2018

Identifiers

DOI

10.1126/SCIENCE.AAC7341

1 reference

2 August 2017

1 reference