(Q34521171)

2 August 2017

title

Cystic fibrosis transmembrane regulator fragments with the Phe508 deletion exert a dual allosteric control over the master kinase CK2. (English)

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2 August 2017

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transmembrane protein

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Mario A Pagano

1

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Giorgio Cozza

object named as

Giorgio Cozza

3

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Lorenzo A Pinna

object named as

Lorenzo A Pinna

8

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Stefania Sarno

object named as

Stefania Sarno

4

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author name string

Oriano Marin

2

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2 August 2017

Flavio Meggio

5

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2 August 2017

Kate J Treharne

6

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2 August 2017

Anil Mehta

7

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2 August 2017

language of work or name

English

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publication date

27 January 2010

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2 August 2017

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2 August 2017

volume

426

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2 August 2017

issue

1

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2 August 2017

page(s)

19-29

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Inhibition of protein kinase CK2 closes the CFTR Cl channel, but has no effect on the cystic fibrosis mutant deltaF508-CFTR.

2 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

Epithelial IgG and its relationship to the loss of F508 in the common mutant form of the cystic fibrosis transmembrane conductance regulator

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

Protein kinase CK2 in health and disease: Protein kinase CK2: from structures to insights.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

Protein kinase CK2 in health and disease: CK2 and its role in Wnt and NF-kappaB signaling: linking development and cancer.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

First inactive conformation of CK2 alpha, the catalytic subunit of protein kinase CK2

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

Extraordinary pleiotropy of protein kinase CK2 revealed by weblogo phosphoproteome analysis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

New protein kinase CK2 inhibitors: jumping out of the catalytic box.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

Small interfering peptide (siP) for in vivo examination of the developing lung interactonome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

Protein kinase CK2 in human diseases.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

Cystic fibrosis as a bowel cancer syndrome and the potential role of CK2.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

Modulation of protein kinase CK2 activity by fragments of CFTR encompassing F508 may reflect functional links with cystic fibrosis pathogenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

CFTR function and prospects for therapy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

The CK2 alpha/CK2 beta interface of human protein kinase CK2 harbors a binding pocket for small molecules

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

The alpha catalytic subunit of protein kinase CK2 is required for mouse embryonic development

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

Pharmacological inhibition of protein kinase CK2 reverts the multidrug resistance phenotype of a CEM cell line characterized by high CK2 level.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

Large-scale phosphorylation analysis of mouse liver

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

The multiple personalities of the regulatory subunit of protein kinase CK2: CK2 dependent and CK2 independent roles reveal a secret identity for CK2beta

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

One-thousand-and-one substrates of protein kinase CK2?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

The protein kinase complement of the human genome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

Protein kinase CK2: structure, regulation and role in cellular decisions of life and death

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

Protein kinase CK2: a challenge to canons

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

Joining the cell survival squad: an emerging role for protein kinase CK2.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

Cystic fibrosis: a worldwide analysis of CFTR mutations--correlation with incidence data and application to screening

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

Crystal structure of human protein kinase CK2: insights into basic properties of the CK2 holoenzyme

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

The crystal structure of the complex of Zea mays alpha subunit with a fragment of human beta subunit provides the clue to the architecture of protein kinase CK2 holoenzyme

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

p53 deficiency and misexpression of protein kinase CK2alpha collaborate in the development of thymic lymphomas in mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

How do protein kinases recognize their substrates?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

Tal-1 induces T cell acute lymphoblastic leukemia accelerated by casein kinase IIalpha.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

Reconstitution of normal and hyperactivated forms of casein kinase-2 by variably mutated beta-subunits.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

Biosynthesis of casein kinase II in lymphoid cell lines

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

Casein kinase II alpha transgene-induced murine lymphoma: relation to theileriosis in cattle.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

A historical view of protein kinase CK2.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

Identification of mutations in regions corresponding to the two putative nucleotide (ATP)-binding folds of the cystic fibrosis gene

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026963

Protein kinase CK2 in mammary gland tumorigenesis

7 July 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090813

Elucidation of the ribonuclease a aggregation process mediated by 3D domain swapping: A computational approach reveals possible new multimeric structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090813

Correctors promote maturation of cystic fibrosis transmembrane conductance regulator (CFTR)-processing mutants by binding to the protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090813

Identification of chemical inhibitors of protein-kinase CK2 subunit interaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090813

Temporal regulation of CFTR expression during ovine lung development: implications for CF gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090813

The Regulatory β Subunit of Protein Kinase CK2 Contributes to the Recognition of the Substrate Consensus Sequence. A Study with an eIF2β-Derived Peptide†

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090813

Unique features of HIV-1 Rev protein phosphorylation by protein kinase CK2 (‘casein kinase-2’)

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090813

Protein Kinase CK2 Mutants Defective in Substrate Recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090813

Basic Residues in the 74-83 and 191-198 Segments of Protein Kinase CK2 Catalytic Subunit are Implicated in Negative but not in Positive Regulation by the beta-Subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090813

Cooperative Modulation of Protein Kinase CK2 by Separate Domains of Its Regulatory β-Subunit†

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090813

Protein kinase CK2: evidence for a protein kinase CK2beta subunit fraction, devoid of the catalytic CK2alpha subunit, in mouse brain and testicles

21 January 2018

1 reference

12 December 2020

The raison d'être of constitutively active protein kinases: the lesson of CK2

1 reference

12 December 2020

Efficient autophosphorylation and phosphorylation of the beta-subunit by casein kinase-2 require the integrity of an acidic cluster 50 residues downstream from the phosphoacceptor site

1 reference

12 December 2020

Casein kinase 2 down-regulation and activation by polybasic peptides are mediated by acidic residues in the 55-64 region of the beta-subunit. A study with calmodulin as phosphorylatable substrate

1 reference

12 December 2020

Asymmetric expression of protein kinase CK2 subunits in human kidney tumors

1 reference

12 December 2020

Identifiers

DOI

10.1042/BJ20090813

1 reference

2 August 2017

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2 August 2017

1 reference