(Q34525952)

2 August 2017

1 reference

title

Target validation of G-protein coupled receptors (English)

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G protein-coupled receptor

2 August 2017

main subject

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author name string

Alan Wise

series ordinal

1

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2 August 2017

Katy Gearing

series ordinal

2

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2 August 2017

Stephen Rees

series ordinal

3

1 reference

2 August 2017

publication date

1 February 2002

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2 August 2017

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2 August 2017

volume

7

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2 August 2017

issue

4

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2 August 2017

page(s)

235-246

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Drug discovery: a historical perspective

2 August 2017

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The Sequence of the Human Genome

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7 January 2021

A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis

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7 January 2021

Sphingosylphosphorylcholine is a ligand for ovarian cancer G-protein-coupled receptor 1.

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7 January 2021

Identification of a molecular target of psychosine and its role in globoid cell formation

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7 January 2021

RETRACTED: Lysophosphatidylcholine as a ligand for the immunoregulatory receptor G2A.

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7 January 2021

Sphingosylphosphorylcholine and lysophosphatidylcholine are ligands for the G protein-coupled receptor GPR4

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7 January 2021

Receptor for the pain modulatory neuropeptides FF and AF is an orphan G protein-coupled receptor

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7 January 2021

Current developments in G-protein-coupled receptors

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7 January 2021

Tools for investigating functional interactions between ligands and G-protein-coupled receptors

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7 January 2021

Functional coupling of mammalian receptors to the yeast mating pathway using novel yeast/mammalian G protein alpha-subunit chimeras

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7 January 2021

G alpha 15 and G alpha 16 couple a wide variety of receptors to phospholipase C

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7 January 2021

A method for evaluating the effects of ligands upon Gs protein-coupled receptors using a recombinant melanophore-based bioassay

1 reference

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7 January 2021

Receptor for motilin identified in the human gastrointestinal system

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7 January 2021

Melanin-concentrating hormone is the cognate ligand for the orphan G-protein-coupled receptor SLC-1

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7 January 2021

Molecular cloning and functional characterization of MCH2, a novel human MCH receptor

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7 January 2021

Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14

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7 January 2021

Identification of receptors for neuromedin U and its role in feeding

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7 January 2021

Neuromedin U is a potent agonist at the orphan G protein-coupled receptor FM3

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7 January 2021

Identification of the natural ligand of an orphan G-protein-coupled receptor involved in the regulation of vasoconstriction

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7 January 2021

Purification and identification of neuromedin U as an endogenous ligand for an orphan receptor GPR66 (FM3).

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7 January 2021

Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1

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7 January 2021

Edg-2/Vzg-1 couples to the yeast pheromone response pathway selectively in response to lysophosphatidic acid

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7 January 2021

Characterization of a novel subtype of human G protein-coupled receptor for lysophosphatidic acid

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7 January 2021

Sphingosine 1-phosphate-induced cell rounding and neurite retraction are mediated by the G protein-coupled receptor H218

1 reference

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7 January 2021

Edg-6 as a putative sphingosine 1-phosphate receptor coupling to Ca(2+) signaling pathway

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7 January 2021

Characterization of a novel sphingosine 1-phosphate receptor, Edg-8

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7 January 2021

Characterization of the human cysteinyl leukotriene 2 receptor

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7 January 2021

Molecular cloning and characterization of a novel type of histamine receptor preferentially expressed in leukocytes

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7 January 2021

Trace amines: identification of a family of mammalian G protein-coupled receptors

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7 January 2021

A G protein-coupled receptor for UDP-glucose

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7 January 2021

Molecular characterization of the melanin-concentrating-hormone receptor

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7 January 2021

Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor

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7 January 2021

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

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7 January 2021

The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity

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7 January 2021

A prolactin-releasing peptide in the brain

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7 January 2021

Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor

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7 January 2021

Ghrelin is a growth-hormone-releasing acylated peptide from stomach

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7 January 2021

Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptor

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7 January 2021

AXOR12, a novel human G protein-coupled receptor, activated by the peptide KiSS-1

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7 January 2021

Molecular cloning of a novel G protein-coupled receptor that may belong to the neuropeptide receptor family

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7 January 2021

Independent feeding and metabolic actions of orexins in mice

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7 January 2021

The effect of the orexins on food intake: comparison with neuropeptide Y, melanin-concentrating hormone and galanin

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7 January 2021

Orexin A activates locus coeruleus cell firing and increases arousal in the rat.

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7 January 2021

Down regulation of the prepro-orexin gene expression in genetically obese mice

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7 January 2021

SB-334867-A: the first selective orexin-1 receptor antagonist

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7 January 2021

CCR3 blockade as a new therapy for asthma

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7 January 2021

Human G protein-coupled receptor GPR-9-6/CC chemokine receptor 9 is selectively expressed on intestinal homing T lymphocytes, mucosal lymphocytes, and thymocytes and is required for thymus-expressed chemokine-mediated chemotaxis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2801%2902131-6

7 January 2021

Functional deletion of the CCR5 receptor by intracellular immunization produces cells that are refractory to CCR5-dependent HIV-1 infection and cell fusion

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2801%2902131-6

7 January 2021

CXCR4 mediates entry and productive infection of syncytia-inducing (X4) HIV-1 strains in primary macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2801%2902131-6

7 January 2021

The experimental use of antisense oligonucleotides: a guide for the perplexed

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2801%2902131-6

7 January 2021

G protein-coupled receptors: functional and mechanistic insights through altered gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2801%2902131-6

7 January 2021

Differential blockade of morphine and morphine-6 beta-glucuronide analgesia by antisense oligodeoxynucleotides directed against MOR-1 and G-protein alpha subunits in rats

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2801%2902131-6

7 January 2021

Decreased insulin content and secretion in RIN 1046-38 cells overexpressing alpha 2-adrenergic receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2801%2902131-6

7 January 2021

Rewarding effects of opiates are absent in mice lacking the receptor for substance P.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2801%2902131-6

7 January 2021

Mice lacking the M3 muscarinic acetylcholine receptor are hypophagic and lean.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2801%2902131-6

7 January 2021

Facilitation of long-term potentiation and memory in mice lacking nociceptin receptors.

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https://api.crossref.org/works/10.1016%2FS1359-6446%2801%2902131-6

7 January 2021

Altered emotional behavior in PACAP-type-I-receptor-deficient mice

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https://api.crossref.org/works/10.1016%2FS1359-6446%2801%2902131-6

7 January 2021

Epileptogenesis and enhanced prepulse inhibition in GABA(B1)-deficient mice

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https://api.crossref.org/works/10.1016%2FS1359-6446%2801%2902131-6

7 January 2021

Engineering receptors activated solely by synthetic ligands (RASSLs).

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2801%2902131-6

7 January 2021

Novel neurotransmitters as natural ligands of orphan G-protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2801%2902131-6

7 January 2021

alpha-Latrotoxin stimulates exocytosis by the interaction with a neuronal G-protein-coupled receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2801%2902131-6

7 January 2021

RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2801%2902131-6

7 January 2021

Molecular cloning and characterization of the human anaphylatoxin C3a receptor

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https://api.crossref.org/works/10.1016%2FS1359-6446%2801%2902131-6

7 January 2021

Characterization of the human cysteinyl leukotriene CysLT1 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2801%2902131-6

7 January 2021

Identification and characterization of two G protein-coupled receptors for neuropeptide FF

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2801%2902131-6

7 January 2021

ADP is the cognate ligand for the orphan G protein-coupled receptor SP1999

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2801%2902131-6

7 January 2021

Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2801%2902131-6

7 January 2021

Orphan G-protein-coupled receptors: the next generation of drug targets?

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2801%2902131-6

7 January 2021

10.1016/S1359-6446(01)02131-6

Identifiers

DOI

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2 August 2017

1 reference