(Q34529310)

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Characterization of the E138K resistance mutation in HIV-1 reverse transcriptase conferring susceptibility to etravirine in B and non-B HIV-1 subtypes

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Characterization of the E138K resistance mutation in HIV-1 reverse transcriptase conferring susceptibility to etravirine in B and non-B HIV-1 subtypes (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

3

object named as

Mark A Wainberg

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Maureen Oliveira

2

object named as

Maureen Oliveira

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

4

object named as

Bluma G Brenner

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

5

object named as

Daniela Moisi

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Eugene L Asahchop

1

object named as

Eugene L Asahchop

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

author name string

Thomas d'Aquin Toni

6

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Cecile L Tremblay

7

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

language of work or name

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publication date

6 December 2010

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Europe PubMed Central

PubMed publication ID

2 August 2017

number of pages

8

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based on heuristic

inferred from page(s)

Antimicrobial Agents and Chemotherapy

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Europe PubMed Central

PubMed publication ID

2 August 2017

55

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

600-607

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Patients infected with HIV type 1 subtype CRF01_AE and failing first-line nevirapine- and efavirenz-based regimens demonstrate considerable cross-resistance to etravirine

1 reference

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The M230L nonnucleoside reverse transcriptase inhibitor resistance mutation in HIV-1 reverse transcriptase impairs enzymatic function and viral replicative capacity.

1 reference

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In vitro resistance development for RO-0335, a novel diphenylether nonnucleoside reverse transcriptase inhibitor

1 reference

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7 July 2018

Suboptimal etravirine activity is common during failure of nevirapine-based combination antiretroviral therapy in a cohort infected with non-B subtype HIV-1.

1 reference

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Impact of human leukocyte antigen-B*51-restricted cytotoxic T-lymphocyte pressure on mutation patterns of nonnucleoside reverse transcriptase inhibitor resistance

1 reference

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Resistance profile of etravirine: combined analysis of baseline genotypic and phenotypic data from the randomized, controlled Phase III clinical studies

1 reference

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7 July 2018

Resistance-associated mutations to etravirine (TMC-125) in antiretroviral-naïve patients infected with non-B HIV-1 subtypes

1 reference

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TMC278, a next-generation nonnucleoside reverse transcriptase inhibitor (NNRTI), active against wild-type and NNRTI-resistant HIV-1.

1 reference

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7 July 2018

Factors associated with virological response to etravirine in nonnucleoside reverse transcriptase inhibitor-experienced HIV-1-infected patients

1 reference

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Transmitted antiretroviral drug resistance among acute and recent HIV infections in North Carolina from 1998 to 2007

1 reference

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7 July 2018

Human immunodeficiency virus type 1 recombinant reverse transcriptase enzymes containing the G190A and Y181C resistance mutations remain sensitive to etravirine.

1 reference

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7 July 2018

A comparison of HIV-1 drug susceptibility as provided by conventional phenotyping and by a phenotype prediction tool based on viral genotype

1 reference

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7 July 2018

Compilation and prevalence of mutations associated with resistance to non-nucleoside reverse transcriptase inhibitors.

1 reference

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7 July 2018

Template usage is responsible for the preferential acquisition of the K65R reverse transcriptase mutation in subtype C variants of human immunodeficiency virus type 1.

1 reference

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7 July 2018

Isolation of drug-resistant mutant HIV variants using tissue culture drug selection.

1 reference

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7 July 2018

Prevalence and risk factors for etravirine resistance among patients failing on non-nucleoside reverse transcriptase inhibitors.

1 reference

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7 July 2018

Structural basis for the improved drug resistance profile of new generation benzophenone non-nucleoside HIV-1 reverse transcriptase inhibitors

1 reference

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Class-sparing regimens for initial treatment of HIV-1 infection

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Global and regional distribution of HIV-1 genetic subtypes and recombinants in 2004.

1 reference

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7 July 2018

Antiviral activity of GW678248, a novel benzophenone nonnucleoside reverse transcriptase inhibitor

1 reference

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7 July 2018

TMC125 displays a high genetic barrier to the development of resistance: evidence from in vitro selection experiments

1 reference

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Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: results of a global collaboration

1 reference

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TMC125, a novel next-generation nonnucleoside reverse transcriptase inhibitor active against nonnucleoside reverse transcriptase inhibitor-resistant human immunodeficiency virus type 1.

1 reference

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7 July 2018

Differential maintenance of the M184V substitution in the reverse transcriptase of human immunodeficiency virus type 1 by various nucleoside antiretroviral agents in tissue culture

1 reference

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Defining a molecular mechanism of synergy between nucleoside and nonnucleoside AIDS drugs.

1 reference

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Competitive fitness of nevirapine-resistant human immunodeficiency virus type 1 mutants

1 reference

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Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection.

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Genetic divergence of human immunodeficiency virus type 1 Ethiopian clade C reverse transcriptase (RT) and rapid development of resistance against nonnucleoside inhibitors of RT.

1 reference

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HIV-1 reverse transcription: a brief overview focused on structure-function relationships among molecules involved in initiation of the reaction

1 reference

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The same mutation that encodes low-level human immunodeficiency virus type 1 resistance to 2',3'-dideoxyinosine and 2',3'-dideoxycytidine confers high-level resistance to the (-) enantiomer of 2',3'-dideoxy-3'-thiacytidine

1 reference

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Comparison of cord blood and peripheral blood mononuclear cells as targets for viral isolation and drug sensitivity studies involving human immunodeficiency virus type 1

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Characterization of genotypic and phenotypic changes in HIV-1-infected patients with virologic failure on an etravirine-containing regimen in the DUET-1 and DUET-2 clinical studies

1 reference

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27 October 2018

Using of nevirapine is associated with intermediate and reduced response to etravirine among HIV-infected patients who experienced virologic failure in a resource-limited setting

1 reference

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Etravirine resistance associated mutations in HIV-infected patients failing efavirenz or nevirapine in the Spanish antiretroviral resistance database

1 reference

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Evaluation of transmitted HIV drug resistance among recently-infected antenatal clinic attendees in four Central African countries

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Raltegravir and etravirine are active against HIV type 1 group O.

1 reference

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Phenotypic impact of resistance mutations on etravirine susceptibility in HIV patients with prior failure to nonnucleoside analogues

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Prevalence of etravirine-associated mutations in clinical samples with resistance to nevirapine and efavirenz.

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Efficacy and safety of TMC125 (etravirine) in treatment-experienced HIV-1-infected patients in DUET-1: 24-week results from a randomised, double-blind, placebo-controlled trial.

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Efficacy and safety of etravirine (TMC125) in patients with highly resistant HIV-1: primary 24-week analysis

1 reference

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HIV-1 subtype C viruses rapidly develop K65R resistance to tenofovir in cell culture.

1 reference

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Validation of a model for the complex of HIV-1 reverse transcriptase with nonnucleoside inhibitor TMC125.

1 reference

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A V106M mutation in HIV-1 clade C viruses exposed to efavirenz confers cross-resistance to non-nucleoside reverse transcriptase inhibitors

1 reference

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Cross-resistance among nonnucleoside reverse transcriptase inhibitors limits recycling efavirenz after nevirapine failure

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Roles of Conformational and Positional Adaptability in Structure-Based Design of TMC125-R165335 (Etravirine) and Related Non-nucleoside Reverse Transcriptase Inhibitors That Are Highly Potent and Effective against Wild-Type and Drug-Resistant HIV-1 V

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9 December 2018

Identifiers

10.1128/AAC.01192-10

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

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