(Q34530720)

2 August 2017

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title

Estrogen, statins, and polyunsaturated fatty acids: similarities in their actions and benefits-is there a common link? (English)

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2 August 2017

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Das UN

1

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2 August 2017

publication date

1 February 2002

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2 August 2017

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2 August 2017

volume

18

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2 August 2017

issue

2

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2 August 2017

page(s)

178-188

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Hormone replacement therapy

2 August 2017

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Estrogen replacement therapy and memory in older women

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17beta-estradiol prevents oxidative stress and decreases blood pressure in ovariectomized rats

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The antioxidant neuroprotective effects of estrogens and phenolic compounds are independent from their estrogenic properties

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Identification of a putative estrogen response element in the gene encoding brain-derived neurotrophic factor.

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Effect of estrogen on brain activation patterns in postmenopausal women during working memory tasks

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7 January 2021

Cognitive decline in women in relation to non-protein-bound oestradiol concentrations

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Oestradiol concentrations in prediction of cognitive decline in women

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Estrogen use and verbal memory in healthy postmenopausal women.

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7 January 2021

Rat ovary produces cytokines during ovulation

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Effect of surgical menopause and estrogen replacement on cytokine release from human blood mononuclear cells

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7 January 2021

Effects of sex hormones on production of interleukin-1 by human peripheral monocytes.

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7 January 2021

Mediation of the immunomodulatory effect of beta-estradiol on inflammatory responses by inhibition of recruitment and activation of inflammatory cells and their gene expression of TNF-alpha and IFN-gamma

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7 January 2021

Estradiol down-regulates LPS-induced cytokine production and NFkB activation in murine macrophages

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7 January 2021

Estrogen decreases TNF gene expression by blocking JNK activity and the resulting production of c-Jun and JunD.

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7 January 2021

Estrogen accelerates cutaneous wound healing associated with an increase in TGF-beta1 levels

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7 January 2021

Hormone replacement therapy and sensitive C-reactive protein concentrations in women with type-2 diabetes

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7 January 2021

Hormone replacement therapy in postmenopausal women and cardiovascular risk

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7 January 2021

Increased bone resorbing activity of peripheral monocyte culture supernatants in elderly women

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7 January 2021

Analysis of gene expression in human bone biopsies by polymerase chain reaction: evidence for enhanced cytokine expression in postmenopausal osteoporosis

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7 January 2021

Increase in cytokine production (IL-1 beta, IL-6, TNF-alpha but not IFN-gamma, GM-CSF or LIF) by stimulated whole blood cells in postmenopausal osteoporosis

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7 January 2021

Estrogen deficiency increases the ability of stromal cells to support murine osteoclastogenesis via an interleukin-1and tumor necrosis factor-mediated stimulation of macrophage colony-stimulating factor production

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7 January 2021

Conditioned medium of estrogen-treated osteoblasts inhibits osteoclast maturation and function in vitro

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7 January 2021

Oestradiol inhibits the release of tumour necrosis factor but not interleukin 6 from adult human osteoblasts in vitro

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7 January 2021

Estrogen inhibits interleukin-6 production and gene expression in a human osteoblastic cell line with high levels of estrogen receptors

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7 January 2021

17 beta-estradiol inhibits interleukin-6 production by bone marrow-derived stromal cells and osteoblasts in vitro: a potential mechanism for the antiosteoporotic effect of estrogens

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7 January 2021

Inflammation-induced cartilage degradation in female rodents. Protective role of sex hormones

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7 January 2021

17beta-estradiol antiinflammatory activity in carrageenan-induced pleurisy

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7 January 2021

Ethinylestradiol does not enhance the expression of nitric oxide synthase in bovine endothelial cells but increases the release of bioactive nitric oxide by inhibiting superoxide anion production.

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7 January 2021

Corticosteroids inhibit the production of inflammatory mediators in immature monocyte-derived DC and induce the development of tolerogenic DC3.

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7 January 2021

Interaction(s) between essential fatty acids, eicosanoids, cytokines, growth factors and free radicals: Relevance to new therapeutic strategies in rheumatoid arthritis and other collagen vascular diseases

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7 January 2021

Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group

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7 January 2021

Statins do more than just lower cholesterol

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7 January 2021

The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals

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7 January 2021

Stimulation of bone formation in vitro and in rodents by statins

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7 January 2021

Protein prenylation: molecular mechanisms and functional consequences

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7 January 2021

Inhibition of proinflammatory cytokine production by pravastatin

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7 January 2021

Effect of statins on C-reactive protein in patients with coronary artery disease

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7 January 2021

Antiatherothrombotic properties of statins: implications for cardiovascular event reduction

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7 January 2021

Statins for prevention of stroke

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7 January 2021

Oral statins and increased bone-mineral density in postmenopausal women

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7 January 2021

Effects of statins on vascular wall: vasomotor function, inflammation, and plaque stability

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7 January 2021

Inhibitory effects of fluvastatin, a new HMG-CoA reductase inhibitor, on the increase in vascular ACE activity in cholesterol-fed rabbits

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7 January 2021

Statins: lower lipids and better bones?

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7 January 2021

Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras.

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7 January 2021

Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro

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7 January 2021

Free radicals, cytokines and nitric oxide in cardiac failure and myocardial infarction

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7 January 2021

C-reactive protein adds to the predictive value of total and HDL cholesterol in determining risk of first myocardial infarction

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7 January 2021

Inflammation, pravastatin, and the risk of coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events (CARE) Investigators.

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7 January 2021

Cholesterol lowering trials in coronary heart disease: frequency of citation and outcome

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7 January 2021

The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigators

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7 January 2021

Cholesterol lowering with statin drugs, risk of stroke, and total mortality. An overview of randomized trials

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7 January 2021

HMG-CoA reductase inhibitors (statins): a promising approach to stroke prevention

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7 January 2021

Effect of HMGcoA reductase inhibitors on stroke. A meta-analysis of randomized, controlled trials

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7 January 2021

Statins and the risk of dementia

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7 January 2021

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

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7 January 2021

The role of cholesterol in the biosynthesis of beta-amyloid

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7 January 2021

Role of the low-density lipoprotein receptor-related protein in beta-amyloid metabolism and Alzheimer disease

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7 January 2021

Association between Alzheimer's disease and the NOS3 gene.

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7 January 2021

Estrogen stakes claim to cognition

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7 January 2021

RETRACTED: A new mechanism of neurodegeneration: a proinflammatory cytokine inhibits receptor signaling by a survival peptide

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7 January 2021

Induction and maintenance of the neuronal cholinergic phenotype in the central nervous system by BMP-9

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7 January 2021

Effect of cis-unsaturated fatty acids on the activity of protein kinases and protein phosphorylation in macrophage tumor (AK-5) cells in vitro

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7 January 2021

Polyunsaturated fatty acids augment free radical generation in tumor cells in vitro

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7 January 2021

Effect of L-arginine-nitric oxide system on the metabolism of essential fatty acids in chemical-induced diabetes mellitus

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7 January 2021

Prevention of chemically induced diabetes mellitus in experimental animals by polyunsaturated fatty acids

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7 January 2021

The brain-lipid-heart connection.

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7 January 2021

How do polyunsaturated fatty acids lower plasma cholesterol levels?

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7 January 2021

Atherosclerosis: an intracellular deficiency in essential fatty acids

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7 January 2021

Beneficial effect of eicosapentaenoic and docosahexaenoic acids in the management of systemic lupus erythematosus and its relationship to the cytokine network

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7 January 2021

Essential fatty acids and osteoporosis

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7 January 2021

Low serum docosahexaenoic acid is a significant risk factor for Alzheimer's dementia.

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7 January 2021

Fish oils and cardiovascular disease

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7 January 2021

Eicosapolyenoic acids of serum lipids of Japanese islanders with low incidence of cardiovascular diseases

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7 January 2021

The inverse relation between fish consumption and 20-year mortality from coronary heart disease

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7 January 2021

Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico

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7 January 2021

Blood pressure, stroke, and coronary heart disease. Part 1, Prolonged differences in blood pressure: prospective observational studies corrected for the regression dilution bias

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7 January 2021

Blood pressure, stroke, and coronary heart disease

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7 January 2021

Assessment of the therapeutic use of n-3 fatty acids in vascular disease and thrombosis

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7 January 2021

Fish oils in the prevention of atherosclerosis

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7 January 2021

The long-term effect of eicosapentaenoic acid on serum levels of lipoprotein (a) and lipids in patients with vascular disease

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7 January 2021

Fatty acid specificity in the inhibition of cell proliferation and its relationship to lipid peroxidation and prostaglandin biosynthesis

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7 January 2021

Eicosapentaenoic acid and docosahexaenoic acid block serotonin-induced smooth muscle cell proliferation

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7 January 2021

Low dose of eicosapentaenoic acid inhibits the exaggerated growth of vascular smooth muscle cells from spontaneously hypertensive rats through suppression of transforming growth factor-beta

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7 January 2021

Fatty acid modulation of endothelial activation

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7 January 2021

The effect of supplementation with omega-3 fatty acids on soluble markers of endothelial function in patients with coronary heart disease

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7 January 2021

Long-term treatment with eicosapentaenoic acid augments both nitric oxide-mediated and non-nitric oxide-mediated endothelium-dependent forearm vasodilatation in patients with coronary artery disease

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7 January 2021

Dietary supplementation with marine omega-3 fatty acids improve systemic large artery endothelial function in subjects with hypercholesterolemia.

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7 January 2021

Protective action of arachidonic acid against alloxan-induced cytotoxicity and diabetes mellitus

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7 January 2021

Effects of dietary gamma-linolenic acid on blood pressure and adrenal angiotensin receptors in hypertensive rats

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7 January 2021

Effect of cis-unsaturated fatty acids, prostaglandins, and free radicals on angiotensin-converting enzyme activity in vitro

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7 January 2021

Kinetics of tumor necrosis factor alpha in plasma and the cardioprotective effect of a monoclonal antibody to tumor necrosis factor alpha in acute myocardial infarction

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7 January 2021

Effect of prostaglandins and their precursors on the proliferation of human lymphocytes and their secretion of tumor necrosis factor and various interleukins

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7 January 2021

The role of TNFalpha and TNF receptors in obesity and insulin resistance

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7 January 2021

Evidence for a role of tumor necrosis factor alpha in disturbances of triglyceride and glucose metabolism predisposing to coronary heart disease.

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7 January 2021

Relationship between plasma leptin levels and the tumor necrosis factor-alpha system in obese subjects

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7 January 2021

The protective role of eicosapentaenoic acid [EPA] in the pathogenesis of nephrolithiasis.

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7 January 2021

Effects of high-fat diet on mature bone mineral content, structure, and mechanical properties

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7 January 2021

Calcium metabolism, osteoporosis and essential fatty acids: a review

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7 January 2021

Epidermal HMG CoA Reductase Activity in Essential Fatty Acid Deficiency: Barrier Requirements Rather Than Eicosanoid Generation Regulate Cholesterol Synthesis

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7 January 2021

Regulation of cholesterol synthesis by oleic and palmitic acid in keratinocytes

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7 January 2021

Effects of dietary alpha- or gamma-linolenic acid on levels and fatty acid compositions of serum and hepatic lipids, and activity and mRNA abundance of 3-hydroxy-3-methylglutaryl CoA reductase in rats

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7 January 2021

Effect of HMG-CoA reductase inhibitors on plasma polyunsaturated fatty acid concentrations in patients with hyperlipidemia

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7 January 2021

Polyunsaturated fatty acids are potent neuroprotectors

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7 January 2021

Inhibition of neuronal apoptosis by docosahexaenoic acid (22:6n-3). Role of phosphatidylserine in antiapoptotic effect

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7 January 2021

Long chain polyunsaturated fatty acids in endogenous depression

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7 January 2021

Fish consumption and major depression

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7 January 2021

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7 January 2021

The ability of aged rats to sustain long-term potentiation is restored when the age-related decrease in membrane arachidonic acid concentration is reversed

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7 January 2021

Dietary docosahexaenoic acid increases cerebral acetylcholine levels and improves passive avoidance performance in stroke-prone spontaneously hypertensive rats

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7 January 2021

Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin

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7 January 2021

Neuromodulation: acetylcholine and memory consolidation.

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7 January 2021

Improvement in functions of the central nervous system by estrogen replacement therapy might be related with an increased nitric oxide production.

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7 January 2021

Modulation of learning, pain thresholds, and thermoregulation in the rat by preparations of free purified alpha-linolenic and linoleic acids: determination of the optimal omega 3-to-omega 6 ratio

1 reference

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7 January 2021

Arachidonic acid stimulates glucose uptake in cerebral cortical astrocytes

1 reference

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7 January 2021

Hippocampal acetylcholine release during memory testing in rats: augmentation by glucose

1 reference

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7 January 2021

Localization of choline acetyltransferase in rat peripheral sympathetic neurons and its coexistence with nitric oxide synthase and neuropeptides.

1 reference

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7 January 2021

Brain insulin receptors and spatial memory. Correlated changes in gene expression, tyrosine phosphorylation, and signaling molecules in the hippocampus of water maze trained rats

1 reference

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7 January 2021

Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo : a specific vascular action of insulin.

1 reference

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7 January 2021

Possible beneficial action(s) of glucose-insulin-potassium regimen in acute myocardial infarction and inflammatory conditions: a hypothesis

1 reference

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7 January 2021

Is insulin an antiinflammatory molecule?

1 reference

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Nongenomic actions of estrogens and xenoestrogens by binding at a plasma membrane receptor unrelated to estrogen receptor alpha and estrogen receptor beta

1 reference

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7 January 2021

Chronic 17beta-estradiol replacement increases nitric oxide-mediated vasodilation of guinea pig coronary microcirculation.

1 reference

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7 January 2021

Effect of 17beta-estradiol on inhibition of platelet aggregation in vitro is mediated by an increase in NO synthesis

1 reference

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7 January 2021

Behavioral effects of estrogen receptor gene disruption in male mice

1 reference

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7 January 2021

Nitric oxide mediates sexual behavior in female rats

1 reference

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7 January 2021

Restoration of ovariectomy-induced osteopenia by nitroglycerin

1 reference

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7 January 2021

Nitric oxide donor alleviates ovariectomy-induced bone loss

1 reference

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7 January 2021

Potentiation of osteoclast bone-resorption activity by inhibition of nitric oxide synthase

1 reference

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7 January 2021

Ovariectomy selectively reduces the concentration of transforming growth factor beta in rat bone: implications for estrogen deficiency-associated bone loss

1 reference

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7 January 2021

Inhibition of carcinoma and melanoma cell growth by type 1 transforming growth factor beta is dependent on the presence of polyunsaturated fatty acids

1 reference

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7 January 2021

Endothelial nitric oxide synthase gene-deficient mice demonstrate marked retardation in postnatal bone formation, reduced bone volume, and defects in osteoblast maturation and activity

1 reference

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7 January 2021

Morphological abnormalities in the brains of estrogen receptor beta knockout mice

1 reference

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7 January 2021

Effects of Simvastatin and omega-3 fatty acids on plasma lipoproteins and lipid peroxidation in patients with combined hyperlipidaemia

1 reference

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7 January 2021

Effect of omega-3 fatty acids and simvastatin on hemostatic risk factors and postprandial hyperlipemia in patients with combined hyperlipemia.

1 reference

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7 January 2021

Bone morphogenetic protein-2 induces cyclin kinase inhibitor p21 and hypophosphorylation of retinoblastoma protein in estradiol-treated MCF-7 human breast cancer cells

1 reference

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7 January 2021

Human bone marrow osteoprogenitors express estrogen receptor-alpha and bone morphogenetic proteins 2 and 4 mRNA during osteoblastic differentiation

1 reference

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7 January 2021

Role of nitric oxide in the inhibition of BMP-2-mediated stimulation of proteoglycan synthesis in articular cartilage

1 reference

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7 January 2021

10.1016/S0899-9007(01)00719-5

Identifiers

DOI

1 reference

2 August 2017

1 reference