(Q34534253)

2 August 2017

1 reference

title

Proton pumping by NADH:ubiquinone oxidoreductase. A redox driven conformational change mechanism? (English)

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2 August 2017

Ulrich Brandt

1

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author name string

Stefan Kerscher

2

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2 August 2017

Stefan Dröse

3

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2 August 2017

Klaus Zwicker

4

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2 August 2017

Volker Zickermann

5

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2 August 2017

language of work or name

English

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publication date

1 June 2003

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2 August 2017

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2 August 2017

volume

545

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2 August 2017

issue

1

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2 August 2017

page(s)

9-17

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Human complex I deficiency: clinical spectrum and involvement of oxygen free radicals in the pathogenicity of the defect

2 August 2017

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21 January 2018

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21 January 2018

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Efficient large scale purification of his-tagged proton translocating NADH:ubiquinone oxidoreductase (complex I) from the strictly aerobic yeast Yarrowia lipolytica

21 January 2018

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21 January 2018

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Definition of the nuclear encoded protein composition of bovine heart mitochondrial complex I. Identification of two new subunits.

21 January 2018

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Procaryotic complex I (NDH-1), an overview

21 January 2018

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The respiratory complex I of bacteria, archaea and eukarya and its module common with membrane-bound multisubunit hydrogenases

21 January 2018

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Transmembrane topology of the NuoL, M and N subunits of NADH:quinone oxidoreductase and their homologues among membrane-bound hydrogenases and bona fide antiporters

21 January 2018

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The Na+-translocating NADH:quinone oxidoreductase (NDH I) from Klebsiella pneumoniae and Escherichia coli: implications for the mechanism of redox-driven cation translocation by complex I.

21 January 2018

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A 12-cistron Escherichia coli operon (hyf) encoding a putative proton-translocating formate hydrogenlyase system

21 January 2018

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The roles of hydrogenases 3 and 4, and the F0F1-ATPase, in H2 production by Escherichia coli at alkaline and acidic pH.

21 January 2018

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Relationship between mitochondrial NADH-ubiquinone reductase and a bacterial NAD-reducing hydrogenase

21 January 2018

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Iron-sulfur clusters/semiquinones in complex I.

21 January 2018

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Disruption of the gene encoding the NADH-binding subunit of NADH: ubiquinone oxidoreductase in Neurospora crassa. Formation of a partially assembled enzyme without FMN and the iron-sulphur cluster N-3.

21 January 2018

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The NADH:ubiquinone oxidoreductase (complex I) from Escherichia coli

21 January 2018

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Complex I: a chimaera of a redox and conformation-driven proton pump?

21 January 2018

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The iron-sulfur clusters in the two related forms of mitochondrial NADH: ubiquinone oxidoreductase made by Neurospora crassa

21 January 2018

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Expression and characterization of the 66-kilodalton (NQO3) iron-sulfur subunit of the proton-translocating NADH-quinone oxidoreductase of Paracoccus denitrificans.

21 January 2018

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Bacterial NADH-quinone oxidoreductases: iron-sulfur clusters and related problems

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Redox properties of the [2Fe-2S] center in the 24 kDa (NQO2) subunit of NADH:ubiquinone oxidoreductase (complex I).

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

The proton-translocating NADH-quinone oxidoreductase (NDH-1) of thermophilic bacterium Thermus thermophilus HB-8. Complete DNA sequence of the gene cluster and thermostable properties of the expressed NQO2 subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Characterization of the iron-sulfur cluster coordinated by a cysteine cluster motif (CXXCXXXCX27C) in the Nqo3 subunit in the proton-translocating NADH-quinone oxidoreductase (NDH-1) of Thermus thermophilus HB-8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Learning from hydrogenases: location of a proton pump and of a second FMN in bovine NADH--ubiquinone oxidoreductase (Complex I).

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Identification of two tetranuclear FeS clusters on the ferredoxin-type subunit of NADH:ubiquinone oxidoreductase (complex I).

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Disruption of iron-sulphur cluster N2 from NADH: ubiquinone oxidoreductase by site-directed mutagenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Exploring the catalytic core of complex I by Yarrowia lipolytica yeast genetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

The origin of cluster N2 of the energy-transducing NADH-quinone oxidoreductase: comparisons of phylogenetically related enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Expression and characterization of the flavoprotein subcomplex composed of 50-kDa (NQO1) and 25-kDa (NQO2) subunits of the proton-translocating NADH-quinone oxidoreductase of Paracoccus denitrificans

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Characterization of two novel redox groups in the respiratory NADH:ubiquinone oxidoreductase (complex I).

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Bovine-heart NADH:ubiquinone oxidoreductase is a monomer with 8 Fe-S clusters and 2 FMN groups

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Energy-dependent Complex I-associated ubisemiquinones in submitochondrial particles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

The iron-sulfur clusters 2 and ubisemiquinone radicals of NADH:ubiquinone oxidoreductase are involved in energy coupling in submitochondrial particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

EPR characterization of ubisemiquinones and iron-sulfur cluster N2, central components of the energy coupling in the NADH-ubiquinone oxidoreductase (complex I) in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Complex I inhibitors as insecticides and acaricides

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Three classes of inhibitors share a common binding domain in mitochondrial complex I (NADH:ubiquinone oxidoreductase).

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

The 49-kDa subunit of NADH-ubiquinone oxidoreductase (Complex I) is involved in the binding of piericidin and rotenone, two quinone-related inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Evidence for a quinone binding site close to the interface between NUOD and NUOB subunits of Complex I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

A central functional role for the 49-kDa subunit within the catalytic core of mitochondrial complex I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

NADH-quinone oxidoreductase: PSST subunit couples electron transfer from iron-sulfur cluster N2 to quinone

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Photolabelling of a mitochondrially encoded subunit of NADH dehydrogenase with [3H]dihydrorotenone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

The ND5 subunit was labeled by a photoaffinity analogue of fenpyroximate in bovine mitochondrial complex I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Mutations in the complex I NDUFS2 gene of patients with cardiomyopathy and encephalomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Leigh syndrome associated with a mutation in the NDUFS7 (PSST) nuclear encoded subunit of complex I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Crystal structure of the nickel-iron hydrogenase from Desulfovibrio gigas

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Unusual ligand structure in Ni-Fe active center and an additional Mg site in hydrogenase revealed by high resolution X-ray structure analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Gas access to the active site of Ni-Fe hydrogenases probed by X-ray crystallography and molecular dynamics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Cryo-electron crystallography of two sub-complexes of bovine complex I reveals the relationship between the membrane and peripheral arms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Three-dimensional structure of bovine NADH:ubiquinone oxidoreductase (complex I) at 22 A in ice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Electron microscopic analysis of the peripheral and membrane parts of mitochondrial NADH dehydrogenase (Complex I)

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Three-dimensional structure of NADH-dehydrogenase from Neurospora crassa by electron microscopy and conical tilt reconstruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Consistent structure between bacterial and mitochondrial NADH:ubiquinone oxidoreductase (complex I).

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

A novel, enzymatically active conformation of the Escherichia coli NADH:ubiquinone oxidoreductase (complex I).

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Purification and molecular and enzymic properties of mitochondrial NADH dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Kinetics of the mitochondrial three-subunit NADH dehydrogenase interaction with hexammineruthenium(III).

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Transmembrane orientation and topology of the NADH:quinone oxidoreductase putative quinone binding subunit NuoH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Cytochrome c oxidase: catalytic cycle and mechanisms of proton pumping--a discussion

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

The protonmotive Q cycle in mitochondria and bacteria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Structure at 2.8 A resolution of F1-ATPase from bovine heart mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Energy transduction in the sodium F-ATPase of Propionigenium modestum

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Catalytic sector of complex I (NADH:ubiquinone oxidoreductase): subunit stoichiometry and substrate-induced conformation changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Function of Conserved Acidic Residues in the PSST Homologue of Complex I (NADH:Ubiquinone Oxidoreductase) fromYarrowia lipolytica

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Proton-translocation by membrane-bound NADH:ubiquinone-oxidoreductase (complex I) through redox-gated ligand conduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Biophysical and structural characterization of proton-translocating NADH-dehydrogenase (complex I) from the strictly aerobic yeast Yarrowia lipolytica

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Binding of detergents and inhibitors to bovine complex I - a novel purification procedure for bovine complex I retaining full inhibitor sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Na+ translocation by the NADH:ubiquinone oxidoreductase (complex I) from Klebsiella pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Organization and evolution of structural elements within complex I

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Structure of the F420H2:quinone oxidoreductase of Archaeoglobus fulgidus identification and overproduction of the F420H2-oxidizing subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Thermodynamic analysis of flavin in mitochondrial NADH:ubiquinone oxidoreductase (complex I)

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Identification of amino acid residues associated with the [2Fe-2S] cluster of the 25 kDa (NQO2) subunit of the proton-translocating NADH-quinone oxidoreductase of Paracoccus denitrificans

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Ubisemiquinones as obligatory intermediates in the electron transfer from NADH to ubiquinone

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Inhibitors of NADH-ubiquinone reductase: an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Structure-activity relationships of some complex I inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Complex I and complex III of mitochondria have common inhibitors acting as ubiquinone antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

A reductant-induced oxidation mechanism for complex I

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Three-dimensional structure of NADH: ubiquinone reductase (complex I) from Neurospora mitochondria determined by electron microscopy of membrane crystals

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Isolation and characterisation of subcomplexes of the mitochondrial NADH:ubiquinone oxidoreductase (complex I)

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Resolution of NADH:ubiquinone oxidoreductase from bovine heart mitochondria into two subcomplexes, one of which contains the redox centers of the enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Resolution of the Membrane Domain of Bovine Complex I into Subcomplexes: Implications for the Structural Organization of the Enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

An analysis of some thermodynamic properties of iron-sulphur centres in site I of mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

EPR studies of the possible binding sites of the cluster N2, semiquinones, and specific inhibitors of the NADH:quinone oxidoreductase (complex I).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

Two binding sites for naturally occurring inhibitors in mitochondrial and bacterial NADH:ubiquinone oxidoreductase (complex I).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900387-9

10.1016/S0014-5793(03)00387-9

7 January 2021

Identifiers

DOI

1 reference

2 August 2017

1 reference