(Q34541645)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25321479%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

title

Numb-dependent integration of pre-TCR and p53 function in T-cell precursor development (English)

1 reference

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21 February 2020

4

1 reference

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21 February 2020

Giulia Franciosa

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25321479%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

author name string

N M Martin-Blanco

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25321479%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

S Checquolo

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25321479%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

F Del Gaudio

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25321479%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

L Di Marcotullio

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25321479%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

A Gulino

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25321479%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

M Canelles

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25321479%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

I Screpanti

9

1 reference

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21 February 2020

publication date

16 October 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25321479%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

published in

Cell Death and Disease

1 reference

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21 February 2020

volume

5

1 reference

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21 February 2020

page(s)

e1472

1 reference

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Creative Commons Attribution 4.0 International

21 February 2020

copyright license

start time

1 October 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Dynamic methylation of Numb by Set8 regulates its binding to p53 and apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237259

Cortical aPKC kinase activity distinguishes neural stem cells from progenitor cells by ensuring asymmetric segregation of Numb

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237259

MDM2 protein-mediated ubiquitination of numb protein: identification of a second physiological substrate of MDM2 that employs a dual-site docking mechanism

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237259

Protein kinase C η is required for T cell activation and homeostatic proliferation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237259

Protein kinase Ctheta is a specific target for inhibition of the HIV type 1 replication in CD4+ T lymphocytes.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237259

Numb activates the E3 ligase Itch to control Gli1 function through a novel degradation signal

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237259

Asymmetric cell division of T cells upon antigen presentation uses multiple conserved mechanisms

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237259

Numb regulates post-endocytic trafficking and degradation of Notch1.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237259

p53 plays a role in mesenchymal differentiation programs, in a cell fate dependent manner

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237259

Mechanisms of asymmetric stem cell division

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237259

NUMB controls p53 tumour suppressor activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237259

aPKC-mediated phosphorylation regulates asymmetric membrane localization of the cell fate determinant Numb

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237259

GCP60 preferentially interacts with a caspase-generated golgin-160 fragment

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237259

Dynamic regulation of mammalian numb by G protein-coupled receptors and protein kinase C activation: Structural determinants of numb association with the cortical membrane

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237259

Asymmetric division and lineage commitment at the level of hematopoietic stem cells: inference from differentiation in daughter cell and granddaughter cell pairs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237259

Drosophila aPKC regulates cell polarity and cell proliferation in neuroblasts and epithelia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237259

Nucleocytoplasmic shuttling of p53 is essential for MDM2-mediated cytoplasmic degradation but not ubiquitination

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237259

Morphine induces desensitization of insulin receptor signaling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237259

mdm2 Is critical for inhibition of p53 during lymphopoiesis and the response to ionizing irradiation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237259

Asymmetric segregation of Numb: a mechanism for neural specification from Drosophila to mammals

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237259

Progenitor cell maintenance requires numb and numblike during mouse neurogenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237259

Phosphorylation of the protein kinase C-theta activation loop and hydrophobic motif regulates its kinase activity, but only activation loop phosphorylation is critical to in vivo nuclear-factor-kappaB induction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237259

Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237259

Vav synergizes with protein kinase C theta to mediate IL-4 gene expression in response to CD28 costimulation in T cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237259

Asymmetric localization of a mammalian numb homolog during mouse cortical neurogenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237259

Phosphorylation on protein kinase C sites inhibits nuclear import of lamin B2.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237259

Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237259

Fluorescence microphotolysis to measure nucleocytoplasmic transport and intracellular mobility

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237259

Expression of p53 during mouse embryogenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237259

Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis.

7 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2014.438

The mammalian Golgi regulates numb signaling in asymmetric cell division by releasing ACBD3 during mitosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2014.438

The Notch regulator Numb links the Notch and TCR signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2014.438

The endocytic adaptor Numb regulates thymus size by modulating pre-TCR signaling during asymmetric division

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2014.438

Asymmetric T lymphocyte division in the initiation of adaptive immune responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2014.438

Protein segregation between dividing hematopoietic progenitor cells in the determination of the symmetry/asymmetry of cell division.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2014.438

High-frequency developmental abnormalities in p53-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2014.438

V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2014.438

Divergent lymphocyte signalling revealed by a powerful new tool for analysis of time-lapse microscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2014.438

Transgenic expression of numb inhibits notch signaling in immature thymocytes but does not alter T cell fate specification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2014.438

Crucial role of the pre-T-cell receptor α gene in development of ap but not γδ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2014.438

Constitutive pre-TCR signaling promotes differentiation through Ca2+ mobilization and activation of NF-kappaB and NFAT

21 January 2018

1 reference

12 December 2020

Splenic marginal zone B-cell and thymic T-cell lymphomas in p53-deficient mice

1 reference

12 December 2020

Pre-TCR signaling and inactivation of p53 induces crucial cell survival pathways in pre-T cells

1 reference

12 December 2020

PKC theta mediates pre-TCR signaling and contributes to Notch3-induced T-cell leukemia

1 reference

12 December 2020

Normal hemopoiesis and lymphopoiesis in the combined absence of numb and numblike

1 reference

12 December 2020

Identifiers

DOI

10.1038/CDDIS.2014.438

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25321479%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25321479%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

PubMed publication ID

25321479

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25321479%20AND%20SRC:MED&resulttype=core&format=json